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Prof. Angelo Campanozzi
University of Foggia, Italy

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Journal article
Published: 28 July 2021 in Nutrients
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The prevalence of primary hypertension in pediatric patients is increasing, especially as a result of the increased prevalence of obesity in children. New diagnostic guidelines for blood pressure were published by the American Academy of Pediatrics (AAP) in 2017 to better define classes of hypertension in children. The aim of our study is to evaluate the impact of new guidelines on diagnosis of hypertension in pediatrics and their capacity to identify the presence of cardiovascular and metabolic risk. Methods: Retrospective clinical and laboratory data from 489 overweight and obese children and adolescents were reviewed. Children were classified according to the 2004 and 2017 AAP guidelines for systolic and diastolic blood pressure. Lipid profile and glucose metabolism data were recorded; triglyceride/HDL ratio (TG/HDL) was calculated as an index of endothelial dysfunction. Hepatic steatosis was detected using the ultrasonographic steatosis score. Results: Children with elevated blood pressure increased from 12.5% with the 2004 AAP to 23.1% with the 2017 AAP criteria (p< 0.001). There was a statistically significant increase in children with high blood pressure in all age groups according to the new cut-off values. Notably, the diagnosis of hypertension according to 2017 AAP criteria had a greater positive association with Hepatic Steatosis (rho 0.2, p< 0.001) and TG/HDL ratio (rho 0.125, p = 0.025). Conclusions: The 2017 AAP tables offer the opportunity to better identify overweight and obese children at risk for organ damage, allowing an earlier and more impactful prevention strategy to be designed.

ACS Style

Irene Rutigliano; Gianpaolo De Filippo; Luigi Pastore; Giovanni Messina; Carlo Agostoni; Angelo Campanozzi. Obesity-Related Hypertension in Pediatrics, the Impact of American Academy of Pediatrics Guidelines. Nutrients 2021, 13, 2586 .

AMA Style

Irene Rutigliano, Gianpaolo De Filippo, Luigi Pastore, Giovanni Messina, Carlo Agostoni, Angelo Campanozzi. Obesity-Related Hypertension in Pediatrics, the Impact of American Academy of Pediatrics Guidelines. Nutrients. 2021; 13 (8):2586.

Chicago/Turabian Style

Irene Rutigliano; Gianpaolo De Filippo; Luigi Pastore; Giovanni Messina; Carlo Agostoni; Angelo Campanozzi. 2021. "Obesity-Related Hypertension in Pediatrics, the Impact of American Academy of Pediatrics Guidelines." Nutrients 13, no. 8: 2586.

Journal article
Published: 05 December 2020 in Nutrition
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Because it is involved in calcium homeostasis, vitamin D is a prohormone with many implications for health, especially bone health. Hypovitaminosis D is considered pandemic worldwide, with important health health consequences. The aim of our study was to evaluate vitamin D levels in children living in a southern region of Italy with high exposure to sunlight for at least 5 mo a year along with contributing factors. A total of 1484 children and adolescents (age 0.02-17.74 y) living in the Apulia region (Southern Italy) were studied. Serum 25-hydroxyvitamin D (25[OH]D) concentrations were assessed and vitamin status defined as follows: deficiency with serum 25(OH)D < 20 ng/mL, insufficiency from 20 to 29.9 ng/mL, and sufficiency with serum 25(OH)D from 30 to 100 ng/mL. The median serum 25(OH)D levels were 20.2 ng/mL (interquartile range, 14.5–26.4 ng/mL): 48.9% of the overall population had 25(OH)D < 20 ng/mL and only 15% had sufficient 25(OH)D values. There was an inverse association between blood levels of 25(OH)D and age (P < 0.001, ρ: −0.113). Significant 25(OH)D variations were recorded according to the season in which blood samples were drawn, but even during summer only 32.6% of analyzed children had sufficient 25(OH)D levels. More than 80% of our population had 25(OH)D less than sufficiency cutoff levels. Results highlight a high prevalence of 25(OH)D deficiency in our area, even during summer. It is important to establish screening, supplementation guidelines, and pediatric cutoff levels to optimize vitamin D status in children, taking into account age, nutritional status, and seasonality.

ACS Style

Irene Rutigliano; Gianpaolo De Filippo; Donatella De Giovanni; Angelo Campanozzi. Is sunlight enough for sufficient vitamin D status in children and adolescents? A survey in a sunny region of southern Italy. Nutrition 2020, 84, 111101 .

AMA Style

Irene Rutigliano, Gianpaolo De Filippo, Donatella De Giovanni, Angelo Campanozzi. Is sunlight enough for sufficient vitamin D status in children and adolescents? A survey in a sunny region of southern Italy. Nutrition. 2020; 84 ():111101.

Chicago/Turabian Style

Irene Rutigliano; Gianpaolo De Filippo; Donatella De Giovanni; Angelo Campanozzi. 2020. "Is sunlight enough for sufficient vitamin D status in children and adolescents? A survey in a sunny region of southern Italy." Nutrition 84, no. : 111101.

Case report
Published: 13 November 2020 in Radiology Case Reports
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Posterior reversible encephalopathy syndrome (PRES) is a variable etiology clinical syndrome with similar neuroimaging results and clinical symptoms. PRES can develop in both adults and children and is characterized by headaches, disorders of consciousness, seizures and especially focal visual disturbances, often associated with hypertensive state. In most cases, symptoms resolve without neurological consequences. The treatment strategy concerns early diagnosis and general measures to correct the underlying cause of PRES. Here, we report a case of PRES that occurs in a 6-year-old child with nephrotic syndrome.

ACS Style

Alessandra Marinari; Anthea Bottoni; Luca Stoppino; Gianpaolo Grilli; Lucia Soldano; Anna Calò; Matilde Cioccia; Giuseppina Mongelli; Barbara Santangelo; Felice Sica; Angelo Campanozzi. Posterior reversible encephalopathy syndrome (PRES) in a 6-year-old child with nephrotic syndrome. Radiology Case Reports 2020, 16, 140 -144.

AMA Style

Alessandra Marinari, Anthea Bottoni, Luca Stoppino, Gianpaolo Grilli, Lucia Soldano, Anna Calò, Matilde Cioccia, Giuseppina Mongelli, Barbara Santangelo, Felice Sica, Angelo Campanozzi. Posterior reversible encephalopathy syndrome (PRES) in a 6-year-old child with nephrotic syndrome. Radiology Case Reports. 2020; 16 (1):140-144.

Chicago/Turabian Style

Alessandra Marinari; Anthea Bottoni; Luca Stoppino; Gianpaolo Grilli; Lucia Soldano; Anna Calò; Matilde Cioccia; Giuseppina Mongelli; Barbara Santangelo; Felice Sica; Angelo Campanozzi. 2020. "Posterior reversible encephalopathy syndrome (PRES) in a 6-year-old child with nephrotic syndrome." Radiology Case Reports 16, no. 1: 140-144.

Review
Published: 31 October 2020 in Brain Sciences
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Neurodevelopmental disorders (NDDs) include diverse neuropathologies characterized by abnormal brain development leading to impaired cognition, communication and social skills. A common feature of NDDs is defective synaptic plasticity, but the underlying molecular mechanisms are only partially known. Several studies have indicated that people’s lifestyles such as diet pattern and physical exercise have significant influence on synaptic plasticity of the brain. Indeed, it has been reported that a high-fat diet (HFD, with 30–50% fat content), which leads to systemic low-grade inflammation, has also a detrimental effect on synaptic efficiency. Interestingly, metabolic alterations associated with obesity in pregnant woman may represent a risk factor for NDDs in the offspring. In this review, we have discussed the potential molecular mechanisms linking the HFD-induced metabolic dysfunctions to altered synaptic plasticity underlying NDDs, with a special emphasis on the roles played by synaptic protein synthesis and mitochondrial functions.

ACS Style

Eduardo Penna; Amelia Pizzella; Fabiano Cimmino; Giovanna Trinchese; Gina Cavaliere; Angela Catapano; Ivana Allocca; Jong Tai Chun; Angelo Campanozzi; Giovanni Messina; Francesco Precenzano; Valentina Lanzara; Antonietta Messina; Vincenzo Monda; Marcellino Monda; Carla Perrone-Capano; Maria Pina Mollica; Marianna Crispino. Neurodevelopmental Disorders: Effect of High-Fat Diet on Synaptic Plasticity and Mitochondrial Functions. Brain Sciences 2020, 10, 805 .

AMA Style

Eduardo Penna, Amelia Pizzella, Fabiano Cimmino, Giovanna Trinchese, Gina Cavaliere, Angela Catapano, Ivana Allocca, Jong Tai Chun, Angelo Campanozzi, Giovanni Messina, Francesco Precenzano, Valentina Lanzara, Antonietta Messina, Vincenzo Monda, Marcellino Monda, Carla Perrone-Capano, Maria Pina Mollica, Marianna Crispino. Neurodevelopmental Disorders: Effect of High-Fat Diet on Synaptic Plasticity and Mitochondrial Functions. Brain Sciences. 2020; 10 (11):805.

Chicago/Turabian Style

Eduardo Penna; Amelia Pizzella; Fabiano Cimmino; Giovanna Trinchese; Gina Cavaliere; Angela Catapano; Ivana Allocca; Jong Tai Chun; Angelo Campanozzi; Giovanni Messina; Francesco Precenzano; Valentina Lanzara; Antonietta Messina; Vincenzo Monda; Marcellino Monda; Carla Perrone-Capano; Maria Pina Mollica; Marianna Crispino. 2020. "Neurodevelopmental Disorders: Effect of High-Fat Diet on Synaptic Plasticity and Mitochondrial Functions." Brain Sciences 10, no. 11: 805.

Original contribution
Published: 21 October 2020 in European Journal of Nutrition
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Purpose The World Health Organization recommends reduction of salt intake to < 5 g/day and the use of iodized salt to prevent iodine deficiency states. A high prevalence of excess salt consumption and an inadequate iodine intake has been previously shown in an Italian pediatric population. It was appropriate, therefore, to analyse in the same population the relationship occurring between salt consumption and iodine intake. Methods The study population was made of 1270 children and adolescents. Estimates of salt consumption and iodine intake were obtained by measuring 24 h urinary sodium and iodine excretion. Results The iodine intake increased gradually across quartiles of salt consumption independently of sex, age and body weight (p < 0.001). Median iodine intake met the European Food Safety Authority adequacy level only in teenagers in the highest quartile of salt consumption (salt intake > 10.2 g/day). We estimated that approximately 65–73% of the total iodine intake was derived from food and 27–35% from iodized salt and that iodized salt made actually only 20% of the total salt intake. Conclusion In this pediatric population, in face of an elevated average salt consumption, the use of iodized salt was still insufficient to ensure an adequate iodine intake, in particular among teenagers. In the perspective of a progressive reduction of total salt intake, the health institutions should continue to support iodoprophylaxis, in the context of the national strategies for salt reduction. In order for these policies to be successful, in addition to educational campaigns, it is needed that the prescriptions contained in the current legislation on iodoprophylaxis are made compelling through specific enforcement measures for all the involved stakeholders.

ACS Style

Roberto Iacone; The MINISAL-GIRCSI Study Group; Paola Iaccarino Idelson; Angelo Campanozzi; Irene Rutigliano; Ornella Russo; Pietro Formisano; Daniela Galeone; Paolo Emidio Macchia; Pasquale Strazzullo. Relationship between salt consumption and iodine intake in a pediatric population. European Journal of Nutrition 2020, 60, 2193 -2202.

AMA Style

Roberto Iacone, The MINISAL-GIRCSI Study Group, Paola Iaccarino Idelson, Angelo Campanozzi, Irene Rutigliano, Ornella Russo, Pietro Formisano, Daniela Galeone, Paolo Emidio Macchia, Pasquale Strazzullo. Relationship between salt consumption and iodine intake in a pediatric population. European Journal of Nutrition. 2020; 60 (4):2193-2202.

Chicago/Turabian Style

Roberto Iacone; The MINISAL-GIRCSI Study Group; Paola Iaccarino Idelson; Angelo Campanozzi; Irene Rutigliano; Ornella Russo; Pietro Formisano; Daniela Galeone; Paolo Emidio Macchia; Pasquale Strazzullo. 2020. "Relationship between salt consumption and iodine intake in a pediatric population." European Journal of Nutrition 60, no. 4: 2193-2202.

Review
Published: 16 October 2020 in Journal of Clinical Medicine
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The accumulation of adipose tissue represents one of the characteristics of obesity, increasing the risk of developing correlated obesity diseases such as cardiovascular disease, type 2 diabetes, cancer, and immune diseases. Visceral adipose tissue accumulation leads to chronic low inflammation inducing an imbalanced adipokine secretion. Among these adipokines, Adiponectin is an important metabolic and inflammatory mediator. It is also known that adipose tissue is influenced by Orexin-A levels, a neuropeptide produced in the lateral hypothalamus. Adiponectin and Orexin-A are strongly decreased in obesity and are associated with metabolic and inflammatory pathways. The aim of this review was to investigate the involvement of the autonomic nervous system focusing on Adiponectin and Orexin-A after bariatric surgery. After bariatric surgery, Adiponectin and Orexin-A levels are strongly increased independently of weight loss showing that hormone increases are also attributable to a rearrangement of metabolic and inflammatory mediators. The restriction of food intake and malabsorption are not sufficient to clarify the clinical effects of bariatric surgery suggesting the involvement of neuro-hormonal feedback loops and also of mediators such as Adiponectin and Orexin-A.

ACS Style

Anna Valenzano; Nicola Tartaglia; Antonio Ambrosi; Domenico Tafuri; Marcellino Monda; Antonietta Messina; Francesco Sessa; Angelo Campanozzi; Vincenzo Monda; Giuseppe Cibelli; Giovanni Messina; Rita Polito. The Metabolic Rearrangements of Bariatric Surgery: Focus on Orexin-A and the Adiponectin System. Journal of Clinical Medicine 2020, 9, 3327 .

AMA Style

Anna Valenzano, Nicola Tartaglia, Antonio Ambrosi, Domenico Tafuri, Marcellino Monda, Antonietta Messina, Francesco Sessa, Angelo Campanozzi, Vincenzo Monda, Giuseppe Cibelli, Giovanni Messina, Rita Polito. The Metabolic Rearrangements of Bariatric Surgery: Focus on Orexin-A and the Adiponectin System. Journal of Clinical Medicine. 2020; 9 (10):3327.

Chicago/Turabian Style

Anna Valenzano; Nicola Tartaglia; Antonio Ambrosi; Domenico Tafuri; Marcellino Monda; Antonietta Messina; Francesco Sessa; Angelo Campanozzi; Vincenzo Monda; Giuseppe Cibelli; Giovanni Messina; Rita Polito. 2020. "The Metabolic Rearrangements of Bariatric Surgery: Focus on Orexin-A and the Adiponectin System." Journal of Clinical Medicine 9, no. 10: 3327.

Letter to the editor
Published: 03 October 2020 in High Blood Pressure & Cardiovascular Prevention
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ACS Style

Irene Rutigliano; Gianpaolo de Filippo; Angelo Campanozzi. The Importance of Reducing Salt Intake in Children, While Respecting the Correct Iodine Supplementation. The Pediatricians' Point of View. High Blood Pressure & Cardiovascular Prevention 2020, 27, 601 -602.

AMA Style

Irene Rutigliano, Gianpaolo de Filippo, Angelo Campanozzi. The Importance of Reducing Salt Intake in Children, While Respecting the Correct Iodine Supplementation. The Pediatricians' Point of View. High Blood Pressure & Cardiovascular Prevention. 2020; 27 (6):601-602.

Chicago/Turabian Style

Irene Rutigliano; Gianpaolo de Filippo; Angelo Campanozzi. 2020. "The Importance of Reducing Salt Intake in Children, While Respecting the Correct Iodine Supplementation. The Pediatricians' Point of View." High Blood Pressure & Cardiovascular Prevention 27, no. 6: 601-602.

Journal article
Published: 05 September 2020 in Sri Lanka Journal of Child Health
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Sri Lanka Journal of Child Health, 2020; 49(3): 276-278

ACS Style

Angelo Campanozzi. Role of nutrition and sedentariness in children's health in times of SARS-COV-2 pandemics – A viewpoint from Italy. Sri Lanka Journal of Child Health 2020, 49, 276 .

AMA Style

Angelo Campanozzi. Role of nutrition and sedentariness in children's health in times of SARS-COV-2 pandemics – A viewpoint from Italy. Sri Lanka Journal of Child Health. 2020; 49 (3):276.

Chicago/Turabian Style

Angelo Campanozzi. 2020. "Role of nutrition and sedentariness in children's health in times of SARS-COV-2 pandemics – A viewpoint from Italy." Sri Lanka Journal of Child Health 49, no. 3: 276.

Short communication
Published: 02 September 2020 in La Presse Médicale Formation
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ACS Style

Marc Aletti; Gianpaolo De Filippo; Corinne Guitton; Angelo Campanozzi; Stephane Lecoules. Calcification splénique et lithiase biliaire chez un garçon de 13 ans. La Presse Médicale Formation 2020, 1, 547 -548.

AMA Style

Marc Aletti, Gianpaolo De Filippo, Corinne Guitton, Angelo Campanozzi, Stephane Lecoules. Calcification splénique et lithiase biliaire chez un garçon de 13 ans. La Presse Médicale Formation. 2020; 1 (5):547-548.

Chicago/Turabian Style

Marc Aletti; Gianpaolo De Filippo; Corinne Guitton; Angelo Campanozzi; Stephane Lecoules. 2020. "Calcification splénique et lithiase biliaire chez un garçon de 13 ans." La Presse Médicale Formation 1, no. 5: 547-548.

Journal article
Published: 01 September 2020 in International Journal of Environmental Research and Public Health
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With the current obesity epidemic and the decline of fitness among school-aged children, the importance of obesity interventions to promote physical activity and healthy habits has become indisputable. The purpose of this study was to assess the efficacy of a school-based multicomponent intervention in increasing physical activity (PA) levels, actual physical abilities, and perceived physical abilities in clinical and nonclinical samples of overweight/obese boys and girls aged 10–12 years. The clinical intervention group (n = 35) participated in a 7-month after-school program in addition to curricular physical education lessons, while the nonclinical control group (n = 29) received usual curricular lessons. Measures included levels of PA and fitness and individual’s perceptions of physical ability. After treatment, the intervention group showed improved PA levels, perceived physical ability, and throwing and jumping task performances compared to the control group. Results indicate that a multicomponent program can improve levels of PA, fitness, and perceived competence of overweight participants. Findings highlight the importance of a comprehensive healthy lifestyle program that includes physical, psychosocial, and behavioral factors and suggest practical implications for educators, trainers, and teachers in identifying best practices targeting childhood obesity.

ACS Style

Milena Morano; Claudio Robazza; Laura Bortoli; Irene Rutigliano; Montse C. Ruiz; Angelo Campanozzi. Physical Activity and Physical Competence in Overweight and Obese Children: An Intervention Study. International Journal of Environmental Research and Public Health 2020, 17, 6370 .

AMA Style

Milena Morano, Claudio Robazza, Laura Bortoli, Irene Rutigliano, Montse C. Ruiz, Angelo Campanozzi. Physical Activity and Physical Competence in Overweight and Obese Children: An Intervention Study. International Journal of Environmental Research and Public Health. 2020; 17 (17):6370.

Chicago/Turabian Style

Milena Morano; Claudio Robazza; Laura Bortoli; Irene Rutigliano; Montse C. Ruiz; Angelo Campanozzi. 2020. "Physical Activity and Physical Competence in Overweight and Obese Children: An Intervention Study." International Journal of Environmental Research and Public Health 17, no. 17: 6370.

Research article
Published: 13 May 2020 in PLoS ONE
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The aims of this study were (1) to investigate whether 6−7-year-old children are accurate in perceiving their actual movement competence, and (2) to examine possible age- and gender-related differences. A total of 603 children (301 girls and 302 boys, aged 6 to 7 years) were assessed on the execution accuracy of six locomotor skills and six object control skills using the Test of Gross Motor Development (TGMD-2). The perceived competence of the same skills, plus six active play activities, was also gauged through the Pictorial Scale of Perceived Movement Skill Competence (PMSC-2). The factorial validity of the TGMD-2 and PMSC-2 scales was preliminarily ascertained using a Bayesian structural equation modeling approach. The relationships between the latent factors of the two instruments were then assessed. Gender and age differences were also examined. The factorial validity of the TGMD-2 and the PMSC-2 was confirmed after some adjustments. A subsequent analysis of the relationship between the latent factors (i.e., locomotor skills and object control) of the two instruments yielded very low estimates. Finally, boys and older children showed better competence in object control skills compared to their counterparts. Weak associations between actual and perceived competence suggest that inaccuracy in children’s perceptions can be likely due to a still limited development of cognitive skills needed for the evaluation of the own competence. From an applied perspective, interventions aimed at improving actual motor competence may also increase children’s self-perceived motor competence and their motivation toward physical activity.

ACS Style

Milena Morano; Laura Bortoli; Montse C. Ruiz; Angelo Campanozzi; Claudio Robazza. Actual and perceived motor competence: Are children accurate in their perceptions? PLoS ONE 2020, 15, e0233190 .

AMA Style

Milena Morano, Laura Bortoli, Montse C. Ruiz, Angelo Campanozzi, Claudio Robazza. Actual and perceived motor competence: Are children accurate in their perceptions? PLoS ONE. 2020; 15 (5):e0233190.

Chicago/Turabian Style

Milena Morano; Laura Bortoli; Montse C. Ruiz; Angelo Campanozzi; Claudio Robazza. 2020. "Actual and perceived motor competence: Are children accurate in their perceptions?" PLoS ONE 15, no. 5: e0233190.

Journal article
Published: 05 February 2020 in Sustainability
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The obesity epidemic and the decline of fitness among children highlights the need for suitable interventions designed to promote Physical Activity (PA) and healthy habits. The purpose of our pilot study was to assess the feasibility of a school-based program among overweight and obese children, by examining changes in their body composition, PA, physical fitness, and some psychosocial determinants of active behavior. An additional objective was to investigate the reciprocal relationship over time between PA and body image. Self-reported PA and health-related fitness tests were administered to 18 overweight and obese children (11.3 ± 0.4 years), before and after a 6-month intervention including nutritional education, skill-learning, playful physical activities, and exercise training. Participants were assessed on body composition, perceived physical ability, body image, and pleasant and unpleasant psychobiosocial states towards PA. After treatment, children showed decreased body mass index, body fat percentage, arm and waist circumferences, and skinfold thickness. Actual and perceived physical abilities, body image, and PA also improved over six months. Cross-lagged correlations suggest body image to be an antecedent to being physically active. Results showed that the multi-component school program may have sustainable benefits in reducing adiposity indicators and improving exercise adherence, physical fitness, and psychological well-being.

ACS Style

Milena Morano; Claudio Robazza; Irene Rutigliano; Laura Bortoli; Montse C. Ruiz; Angelo Campanozzi. Changes in Physical Activity, Motor Performance, and Psychosocial Determinants of Active Behavior in Children: A Pilot School-Based Obesity Program. Sustainability 2020, 12, 1128 .

AMA Style

Milena Morano, Claudio Robazza, Irene Rutigliano, Laura Bortoli, Montse C. Ruiz, Angelo Campanozzi. Changes in Physical Activity, Motor Performance, and Psychosocial Determinants of Active Behavior in Children: A Pilot School-Based Obesity Program. Sustainability. 2020; 12 (3):1128.

Chicago/Turabian Style

Milena Morano; Claudio Robazza; Irene Rutigliano; Laura Bortoli; Montse C. Ruiz; Angelo Campanozzi. 2020. "Changes in Physical Activity, Motor Performance, and Psychosocial Determinants of Active Behavior in Children: A Pilot School-Based Obesity Program." Sustainability 12, no. 3: 1128.

Journal article
Published: 31 October 2019 in The American Journal of Clinical Nutrition
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ACS Style

Angelo Campanozzi; Paolo Emidio Macchia; Gianpaolo De Filippo; Pasquale Strazzullo. Reply to A Olivieri et al. The American Journal of Clinical Nutrition 2019, 110, 1267 -1267.

AMA Style

Angelo Campanozzi, Paolo Emidio Macchia, Gianpaolo De Filippo, Pasquale Strazzullo. Reply to A Olivieri et al. The American Journal of Clinical Nutrition. 2019; 110 (5):1267-1267.

Chicago/Turabian Style

Angelo Campanozzi; Paolo Emidio Macchia; Gianpaolo De Filippo; Pasquale Strazzullo. 2019. "Reply to A Olivieri et al." The American Journal of Clinical Nutrition 110, no. 5: 1267-1267.

Journal article
Published: 01 August 2019 in Digestive and Liver Disease
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ACS Style

Marco Deganello Saccomani; Lorenzo Norsa; Salvatore Oliva; Gian Luigi De’Angelis; Salvatore Accomando; Patrizia Alvisi; Valerio Balassone; Matteo Bramuzzo; Angelo Campanozzi; Francesca Cavataio; Chiara Centenari; Andrea Chiaro; Fabio Cisarò; Michele Citrano; Lorenzo Costa; Rita Cozzali; Grazia D’Adamo; Mario D’Altilia; Teresa Di Chio; Giovanni Di Nardo; Natale Dodaro; Diego Falchetti; Annalisa Famiani; Lorella Fanti; Enrico Felici; Ruggiero Francavilla; Paolo Gandullia; Simona Gatti; Antonino Granata; Maria Teresa Illiceto; Marta Maino; Cristina Malaventura; Cecilia Mantegazza; Stefano Martelossi; Erasmo Miele; Alice Monzani; Alessandro Muscas; Emanuele Nicastro; Paolo Orizio; Caterina Pacenza; Monica Paci; Barbara Parma; Alessandro Raffaele; Alberto Ravelli; Claudio Romano; Caterina Strisciuglio. The pediatric endoscopy practice in Italy: A nationwide survey on behalf of the Italian society of pediatric gastroenterology, hepatology and nutrition (SIGENP). Digestive and Liver Disease 2019, 51, 1203 -1206.

AMA Style

Marco Deganello Saccomani, Lorenzo Norsa, Salvatore Oliva, Gian Luigi De’Angelis, Salvatore Accomando, Patrizia Alvisi, Valerio Balassone, Matteo Bramuzzo, Angelo Campanozzi, Francesca Cavataio, Chiara Centenari, Andrea Chiaro, Fabio Cisarò, Michele Citrano, Lorenzo Costa, Rita Cozzali, Grazia D’Adamo, Mario D’Altilia, Teresa Di Chio, Giovanni Di Nardo, Natale Dodaro, Diego Falchetti, Annalisa Famiani, Lorella Fanti, Enrico Felici, Ruggiero Francavilla, Paolo Gandullia, Simona Gatti, Antonino Granata, Maria Teresa Illiceto, Marta Maino, Cristina Malaventura, Cecilia Mantegazza, Stefano Martelossi, Erasmo Miele, Alice Monzani, Alessandro Muscas, Emanuele Nicastro, Paolo Orizio, Caterina Pacenza, Monica Paci, Barbara Parma, Alessandro Raffaele, Alberto Ravelli, Claudio Romano, Caterina Strisciuglio. The pediatric endoscopy practice in Italy: A nationwide survey on behalf of the Italian society of pediatric gastroenterology, hepatology and nutrition (SIGENP). Digestive and Liver Disease. 2019; 51 (8):1203-1206.

Chicago/Turabian Style

Marco Deganello Saccomani; Lorenzo Norsa; Salvatore Oliva; Gian Luigi De’Angelis; Salvatore Accomando; Patrizia Alvisi; Valerio Balassone; Matteo Bramuzzo; Angelo Campanozzi; Francesca Cavataio; Chiara Centenari; Andrea Chiaro; Fabio Cisarò; Michele Citrano; Lorenzo Costa; Rita Cozzali; Grazia D’Adamo; Mario D’Altilia; Teresa Di Chio; Giovanni Di Nardo; Natale Dodaro; Diego Falchetti; Annalisa Famiani; Lorella Fanti; Enrico Felici; Ruggiero Francavilla; Paolo Gandullia; Simona Gatti; Antonino Granata; Maria Teresa Illiceto; Marta Maino; Cristina Malaventura; Cecilia Mantegazza; Stefano Martelossi; Erasmo Miele; Alice Monzani; Alessandro Muscas; Emanuele Nicastro; Paolo Orizio; Caterina Pacenza; Monica Paci; Barbara Parma; Alessandro Raffaele; Alberto Ravelli; Claudio Romano; Caterina Strisciuglio. 2019. "The pediatric endoscopy practice in Italy: A nationwide survey on behalf of the Italian society of pediatric gastroenterology, hepatology and nutrition (SIGENP)." Digestive and Liver Disease 51, no. 8: 1203-1206.

Review
Published: 01 June 2019 in Nutrition, Metabolism and Cardiovascular Diseases
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Childhood and adolescent obesity has been defined as a planetary epidemic by WHO "globesity". The obesogenic environment, defined as a life environment promoting a high-energy intake and a sedentary lifestyle, significantly contributes to the genesis and the diffusion of the globesity. In the last decades, several authors and working groups tried to develop methodological instruments in order to guarantee a reliable analysis of an obesogenic environment. Their efforts have led to the production of a relatively large number of questionnaires with different characteristics. The general aim of these questionnaires is to identify the factors that significantly contribute to the creation of an obesogenic environment around children and adolescents. As a result of this work, a number of studies were carried out using such questionnaires. Aim of this review is to evaluate ad hoc questionnaires useful to identify and analyze obesogenic environment. The search was carried out in February-March 2017 using the PubMed-Medline and Scopus databases (time interval: the last 10 years). After the selection and verification phases, a total of 14 studies were selected and therefore included in the present review. The questionnaires constructed and validated to analyze multiple constitutive elements of an obesogenic environment at the same time are complex and must be administered by qualified and trained staff. On the other hand, when two or more questionnaires are used to analyze different factors, the questionnaires used are generally shorter, self-administered, and generally easier to understand and interpret.

ACS Style

D. Rendina; A. Campanozzi; G. De Filippo. Methodological approach to the assessment of the obesogenic environment in children and adolescents: A review of the literature. Nutrition, Metabolism and Cardiovascular Diseases 2019, 29, 561 -571.

AMA Style

D. Rendina, A. Campanozzi, G. De Filippo. Methodological approach to the assessment of the obesogenic environment in children and adolescents: A review of the literature. Nutrition, Metabolism and Cardiovascular Diseases. 2019; 29 (6):561-571.

Chicago/Turabian Style

D. Rendina; A. Campanozzi; G. De Filippo. 2019. "Methodological approach to the assessment of the obesogenic environment in children and adolescents: A review of the literature." Nutrition, Metabolism and Cardiovascular Diseases 29, no. 6: 561-571.

Journal article
Published: 01 April 2019 in The American Journal of Clinical Nutrition
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BackgroundIodine is an essential micronutrient for intellectual development in children. Information on iodine intakes based on 24-h urinary iodine excretion (UIE) is scant, because iodine status is only assessed by the measurement of urinary iodine concentration (UIC) in spot urine samples.ObjectivesThe aim of our study was to evaluate the iodine intake of school-age children and adolescents, using UIE measurement in 24-h urine collections.MethodsThe study population included 1270 healthy subjects (677 boys, 593 girls) aged 6–18 y (mean age ± SD: 10.3 ± 2.9) from 10 Italian regions. Daily iodine intake was estimated as UIE/0.92, based on the notion that $\sim$92% of the dietary iodine intake is absorbed. The adequacy of intakes was assessed according to the Dietary Reference Values for iodine of the European Food Safety Authority (EFSA). Body mass index (BMI) and UIC were also measured for each subject.ResultsBased on the scientific opinion of EFSA, 600 of 1270 subjects (47.2%) had a lower than adequate iodine intake, with a higher prevalence among girls (54.6%) compared with boys (40.2%) (P < 0.001). Although UIE and 24-h urinary volumes increased with age (P < 0.001), a progressive decrease in the percentage of subjects with iodine excretion ConclusionsA sizable proportion of our population, especially girls, appeared to be at risk of iodine inadequacy. The simple measurement of UIC could lead to underestimation of the occurrence of iodine deficiency in younger children, because of the age-related smaller urine volumes producing spuriously higher iodine concentrations.

ACS Style

Angelo Campanozzi; Irene Rutigliano; Paolo Emidio Macchia; Gianpaolo De Filippo; Antonio Barbato; Roberto Iacone; Ornella Russo; Giuseppina D'Angelo; Monica Frigeri; Licia Pensabene; Basilio Malamisura; Gaetano Cecere; Maria Micillo; Ruggiero Francavilla; Anna Tetro; Giuliano Lombardi; Lisa Tonelli; Giuseppe Castellucci; Luigi Ferraro; Rita Di Biase; Antonella Lezo; Silvia Salvatore; Silvia Paoletti; Alfonso Siani; Daniela Galeone; Pietro Formisano; Pasquale Strazzullo. Iodine deficiency among Italian children and adolescents assessed through 24-hour urinary iodine excretion. The American Journal of Clinical Nutrition 2019, 109, 1080 -1087.

AMA Style

Angelo Campanozzi, Irene Rutigliano, Paolo Emidio Macchia, Gianpaolo De Filippo, Antonio Barbato, Roberto Iacone, Ornella Russo, Giuseppina D'Angelo, Monica Frigeri, Licia Pensabene, Basilio Malamisura, Gaetano Cecere, Maria Micillo, Ruggiero Francavilla, Anna Tetro, Giuliano Lombardi, Lisa Tonelli, Giuseppe Castellucci, Luigi Ferraro, Rita Di Biase, Antonella Lezo, Silvia Salvatore, Silvia Paoletti, Alfonso Siani, Daniela Galeone, Pietro Formisano, Pasquale Strazzullo. Iodine deficiency among Italian children and adolescents assessed through 24-hour urinary iodine excretion. The American Journal of Clinical Nutrition. 2019; 109 (4):1080-1087.

Chicago/Turabian Style

Angelo Campanozzi; Irene Rutigliano; Paolo Emidio Macchia; Gianpaolo De Filippo; Antonio Barbato; Roberto Iacone; Ornella Russo; Giuseppina D'Angelo; Monica Frigeri; Licia Pensabene; Basilio Malamisura; Gaetano Cecere; Maria Micillo; Ruggiero Francavilla; Anna Tetro; Giuliano Lombardi; Lisa Tonelli; Giuseppe Castellucci; Luigi Ferraro; Rita Di Biase; Antonella Lezo; Silvia Salvatore; Silvia Paoletti; Alfonso Siani; Daniela Galeone; Pietro Formisano; Pasquale Strazzullo. 2019. "Iodine deficiency among Italian children and adolescents assessed through 24-hour urinary iodine excretion." The American Journal of Clinical Nutrition 109, no. 4: 1080-1087.

Review
Published: 11 January 2019 in Italian Journal of Pediatrics
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Functional gastrointestinal disorders (FGIDs) are characterized by chronic/recurrent gastrointestinal symptoms not related to organic disorders. Due to the limited treatment options and to the perception of subjects with FGIDs suffering from a food intolerance, in recent years there has been an increase in the self-prescription of elimination diets, especially gluten free diet (GFD), for the treatment of these disorders. For this reason, we decided to perform this systematic review with the aim to evaluate the available evidence on the effects of a GFD on gastrointestinal symptoms, in subjects with FGIDs. Cochrane Library and MEDLINE (via PubMed) databases were searched, from inception to March 2018, using the MeSH terms “functional gastrointestinal disorder OR irritable bowel syndrome AND gluten”. We included all the clinical trials published in English and evaluating the effects of a GFD in subjects with FGIDs diagnosed according to the Rome II, III, and IV criteria. Eleven trials were eligible (3 prospective trials, 8 single or double-blind placebo-controlled trials), with 10/11 trials including adult subjects with irritable bowel syndrome (IBS) or FGIDs. Most of the prospective studies found an effect of GFD on gastrointestinal symptoms control. Nevertheless, 1 trial failed to find an association between gluten and GI symptoms when FODMAPs (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) content was simultaneously reduced in the diet, and 2 trials reported a worsening of symptoms during placebo administration. The results of the different trials are difficult to compare due to discrepancies in the study protocols regarding the amount and type of gluten administered, the duration of the gluten challenge, the type of placebo used, and the duration of the challenge itself. According to our results, gluten may contribute to the occurrence of gastrointestinal symptoms in patients with FGIDs, particularly in those with IBS. Nevertheless, the results of the currently available trials are difficult to compare due to the lack of standardization in the study designs. For this reason, it is still not possible to recommend the use of the GFD in the routine management of FGIDs.

ACS Style

Elena Scarpato; Renata Auricchio; Francesca Penagini; Angelo Campanozzi; Gian Vincenzo Zuccotti; Riccardo Troncone. Efficacy of the gluten free diet in the management of functional gastrointestinal disorders: a systematic review on behalf of the Italian Society of Paediatrics. Italian Journal of Pediatrics 2019, 45, 9 .

AMA Style

Elena Scarpato, Renata Auricchio, Francesca Penagini, Angelo Campanozzi, Gian Vincenzo Zuccotti, Riccardo Troncone. Efficacy of the gluten free diet in the management of functional gastrointestinal disorders: a systematic review on behalf of the Italian Society of Paediatrics. Italian Journal of Pediatrics. 2019; 45 (1):9.

Chicago/Turabian Style

Elena Scarpato; Renata Auricchio; Francesca Penagini; Angelo Campanozzi; Gian Vincenzo Zuccotti; Riccardo Troncone. 2019. "Efficacy of the gluten free diet in the management of functional gastrointestinal disorders: a systematic review on behalf of the Italian Society of Paediatrics." Italian Journal of Pediatrics 45, no. 1: 9.

Journal article
Published: 07 March 2018 in Acta Paediatrica
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No data are available on caffeine consumption among Italian adolescents. We investigated caffeine intake from coffee, soft drinks and energy drinks in a sample of Italian adolescents and determined if they exceeded the recommended limits. The study comprised 1213 adolescents with a mean age of 15.1 years (range 12–19) from four schools in Foggia, southern Italy. Caffeine intake was assessed using an anonymous self-reported questionnaire during the 2013/2014 school year. We calculated the percentage of daily caffeine consumers, their mean intake of caffeine from beverages and the contribution of each beverage category to the total caffeine intake. Approximately 76% of the sample consumed caffeine every day, amounting to 125.5 ± 69.2 mg/day and 2.1 ± 1.2 mg/kg/day. When we applied the reference values from the Academy of Pediatrics, we found that 46% of the adolescents exceeded the recommended upper limits. Coffee was the most frequently consumed caffeinated drink and the main contributor to daily caffeine intake. More than three quarters (76%) of the Italian adolescents in our study drank coffee on a daily basis and nearly half (46%) exceeded the recommended upper limits. Strategies are needed to reduce caffeine consumption by adolescents.

ACS Style

Barbara Santangelo; Rosa Lapolla; Irene Rutigliano; Massimo Pettoello Mantovani; Angelo Campanozzi. Nearly half of the adolescents in an Italian school-based study exceeded the recommended upper limits for daily caffeine consumption. Acta Paediatrica 2018, 107, 1055 -1059.

AMA Style

Barbara Santangelo, Rosa Lapolla, Irene Rutigliano, Massimo Pettoello Mantovani, Angelo Campanozzi. Nearly half of the adolescents in an Italian school-based study exceeded the recommended upper limits for daily caffeine consumption. Acta Paediatrica. 2018; 107 (6):1055-1059.

Chicago/Turabian Style

Barbara Santangelo; Rosa Lapolla; Irene Rutigliano; Massimo Pettoello Mantovani; Angelo Campanozzi. 2018. "Nearly half of the adolescents in an Italian school-based study exceeded the recommended upper limits for daily caffeine consumption." Acta Paediatrica 107, no. 6: 1055-1059.

Journal article
Published: 08 February 2018 in Türk Pediatri Arşivi
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The findings of this preliminary study align with data from the literature suggesting that the investigation of tumor necrosis factor-α, interleukin-10, and interleukin-12 in cow's milk protein-stimulated peripheral blood mononuclear cell cultures of children may be taken in further consideration to explore whether they might have a predictive role for cow's milk protein allergy. Further studies are therefore needed to extensively investigate this issue.

ACS Style

Maria D’Apolito; Angelo Campanozzi; Ida Giardino; Massimo Pettoello Mantovani. Levels of inflammatory cytokines from peripheral blood mononuclear cells of children with cow’s milk protein allergy. Türk Pediatri Arşivi 2018, 52, 208 -212.

AMA Style

Maria D’Apolito, Angelo Campanozzi, Ida Giardino, Massimo Pettoello Mantovani. Levels of inflammatory cytokines from peripheral blood mononuclear cells of children with cow’s milk protein allergy. Türk Pediatri Arşivi. 2018; 52 (4):208-212.

Chicago/Turabian Style

Maria D’Apolito; Angelo Campanozzi; Ida Giardino; Massimo Pettoello Mantovani. 2018. "Levels of inflammatory cytokines from peripheral blood mononuclear cells of children with cow’s milk protein allergy." Türk Pediatri Arşivi 52, no. 4: 208-212.

Multicenter study
Published: 09 November 2017 in Clinical Gastroenterology and Hepatology
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Background & Aims Little is known about the prevalence of functional gastrointestinal disorders (FGIDs) in children from the Mediterranean area of Europe. We aimed to assess the prevalence of FGIDs in children and adolescents in this region. Methods We collected data on 13,750 children (4–18 years old) enrolled in the Mediterranean–European Area Project, a school-based health study performed in Croatia, Greece, Israel, Italy, Jordan, Lebanon, Macedonia, Serbia, and Spain. Data were collected from March to June and in September of 2016. We analyzed data from 6602 students 4 to 10 years old (group A; mean age, 7.7 ± 1.9 y), and 7148 subjects 11 to 18 years old (group B; mean age, 13.8 ± 2.1 y). Children with FGIDs were identified based on answers to questionnaires on pediatric gastrointestinal symptoms, selected based on Rome III criteria. Results In group A, the prevalence of FGIDs was 20.7%. The most frequent disorders were functional constipation (11.7%), irritable bowel syndrome (IBS, 4%), aerophagia (3.5%), and abdominal migraine (3.1%). The prevalence of abdominal migraine was significantly higher in girls than in boys (P = .007). In group B, the overall prevalence of FGIDs was 26.6%. The most frequent disorders were functional constipation (13.1%), abdominal migraine (7.8%), aerophagia (6.3%), and IBS (5.6%). In group B, FGIDs had a higher prevalence among girls than boys (P< .001). In both groups, we found significant differences in the prevalence of specific disorders among specific countries. Conclusions In an analysis of data on children 4 to 18 years old from the Mediterranean–European Area Project, we found FGIDs to be more frequent in girls. Functional constipation, aerophagia, abdominal migraine, and IBS are the most common disorders. However, the prevalence of FGIDs varies significantly among countries.

ACS Style

Elena Scarpato; Sanja Kolacek; Danijela Jojkic-Pavkov; Vlatka Konjik; Nataša Živković; Enriqueta Roman; Aco Kostovski; Nikolina Zdraveska; Eyad Altamimi; Alexandra Papadopoulou; Thomai Karagiozoglou-Lampoudi; Raanan Shamir; Michal Rozenfeld Bar Lev; Aziz Koleilat; Sirin Mneimneh; Dario Bruzzese; Rosaura Leis; Annamaria Staiano; Panayota Kafritsa; Sandra Brusa; Angelo Campanozzi; Claudio Romano; Silvia Salvatore; Evelina Kotzakioulafi; Josefa Barrio; Maria Luz Cilleruelo; Mercedes Juste; Carolina Gutiérrez-Junquera; Tena Trbojević; Lana Ivković. Prevalence of Functional Gastrointestinal Disorders in Children and Adolescents in the Mediterranean Region of Europe. Clinical Gastroenterology and Hepatology 2017, 16, 870 -876.

AMA Style

Elena Scarpato, Sanja Kolacek, Danijela Jojkic-Pavkov, Vlatka Konjik, Nataša Živković, Enriqueta Roman, Aco Kostovski, Nikolina Zdraveska, Eyad Altamimi, Alexandra Papadopoulou, Thomai Karagiozoglou-Lampoudi, Raanan Shamir, Michal Rozenfeld Bar Lev, Aziz Koleilat, Sirin Mneimneh, Dario Bruzzese, Rosaura Leis, Annamaria Staiano, Panayota Kafritsa, Sandra Brusa, Angelo Campanozzi, Claudio Romano, Silvia Salvatore, Evelina Kotzakioulafi, Josefa Barrio, Maria Luz Cilleruelo, Mercedes Juste, Carolina Gutiérrez-Junquera, Tena Trbojević, Lana Ivković. Prevalence of Functional Gastrointestinal Disorders in Children and Adolescents in the Mediterranean Region of Europe. Clinical Gastroenterology and Hepatology. 2017; 16 (6):870-876.

Chicago/Turabian Style

Elena Scarpato; Sanja Kolacek; Danijela Jojkic-Pavkov; Vlatka Konjik; Nataša Živković; Enriqueta Roman; Aco Kostovski; Nikolina Zdraveska; Eyad Altamimi; Alexandra Papadopoulou; Thomai Karagiozoglou-Lampoudi; Raanan Shamir; Michal Rozenfeld Bar Lev; Aziz Koleilat; Sirin Mneimneh; Dario Bruzzese; Rosaura Leis; Annamaria Staiano; Panayota Kafritsa; Sandra Brusa; Angelo Campanozzi; Claudio Romano; Silvia Salvatore; Evelina Kotzakioulafi; Josefa Barrio; Maria Luz Cilleruelo; Mercedes Juste; Carolina Gutiérrez-Junquera; Tena Trbojević; Lana Ivković. 2017. "Prevalence of Functional Gastrointestinal Disorders in Children and Adolescents in the Mediterranean Region of Europe." Clinical Gastroenterology and Hepatology 16, no. 6: 870-876.