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There are numerous dietary recommendations during pregnancy. However, there are limited recommendations during the lactation period, a nutritionally vulnerable period for women. The Mediterranean Diet and adherence to the Healthy Food Pyramid (HFP) is considered as the standard for healthy eating. In this study, we investigated the differences in adherence to the HFP in pregnant, lactating, and non-pregnant/non-lactating (NPNL) women concerning sociodemographic factors. A sociodemographic and nutritional and lifestyle questionnaire (AP-Q) were used to assess adherence to the HFP, including lifestyle. The AP-Q score ranges from 0 to 10 meaning the higher the score, the greater the adherence to the HFP. Lactating women had the lowest AP-Q score (6.13 [5.31; 6.82]) compared to the pregnant (6.39 [5.56; 7.05]) and NPNL women (6.27 [5.43; 6.88]), while pregnant women had the highest scores. Maternal age was positively correlated with AP-Q score in pregnant (rho = 0.22; p-Value < 0.001) and lactating women (rho = 0.18; p-Value < 0.001), but not in NPNL women. Educational level and monthly income had a positive influence on the degree of adherence to the HFP. In conclusion, breastfeeding mothers of young age and low socioeconomic and educational level would be the target population to carry out nutritional interventions that improve their adherence to the HFP. The knowledge gained from this study can help to design recommendation guidelines and nutritional educational interventions for a given population.
Andrea Gila-Díaz; Ariadna Witte Castro; Gloria Herranz Carrillo; Pratibha Singh; William Yakah; Silvia Arribas; David Ramiro-Cortijo. Assessment of Adherence to the Healthy Food Pyramid in Pregnant and Lactating Women. Nutrients 2021, 13, 2372 .
AMA StyleAndrea Gila-Díaz, Ariadna Witte Castro, Gloria Herranz Carrillo, Pratibha Singh, William Yakah, Silvia Arribas, David Ramiro-Cortijo. Assessment of Adherence to the Healthy Food Pyramid in Pregnant and Lactating Women. Nutrients. 2021; 13 (7):2372.
Chicago/Turabian StyleAndrea Gila-Díaz; Ariadna Witte Castro; Gloria Herranz Carrillo; Pratibha Singh; William Yakah; Silvia Arribas; David Ramiro-Cortijo. 2021. "Assessment of Adherence to the Healthy Food Pyramid in Pregnant and Lactating Women." Nutrients 13, no. 7: 2372.
Cardiovascular disease remains a leading cause of mortality worldwide. Unresolved inflammation plays a critical role in cardiovascular diseases development. Specialized Pro-Resolving Mediators (SPMs), derived from long chain polyunsaturated fatty acids (LCPUFAs), enhances the host defense, by resolving the inflammation and tissue repair. In addition, SPMs also have anti-inflammatory properties. These physiological effects depend on the availability of LCPUFAs precursors and cellular metabolic balance. Most of the studies have focused on the impact of SPMs in adult cardiovascular health and diseases. In this review, we discuss LCPUFAs metabolism, SPMs, and their potential effect on cardiovascular health and diseases primarily focusing in neonates. A better understanding of the role of these SPMs in cardiovascular health and diseases in neonates could lead to the development of novel therapeutic approaches in cardiovascular dysfunction.
Andrea Gila-Diaz; Gloria Carrillo; Pratibha Singh; David Ramiro-Cortijo. Specialized Pro-Resolving Lipid Mediators in Neonatal Cardiovascular Physiology and Diseases. Antioxidants 2021, 10, 933 .
AMA StyleAndrea Gila-Diaz, Gloria Carrillo, Pratibha Singh, David Ramiro-Cortijo. Specialized Pro-Resolving Lipid Mediators in Neonatal Cardiovascular Physiology and Diseases. Antioxidants. 2021; 10 (6):933.
Chicago/Turabian StyleAndrea Gila-Diaz; Gloria Carrillo; Pratibha Singh; David Ramiro-Cortijo. 2021. "Specialized Pro-Resolving Lipid Mediators in Neonatal Cardiovascular Physiology and Diseases." Antioxidants 10, no. 6: 933.
The first month of lactation is a vulnerable nutritional period for the mother. Our aims were (1) to evaluate the nutritional status of breastfeeding women in the first month of lactation, and (2) to explore different aspects of nutrition and lifestyle through a multidimensional approach. A total of 30 healthy breastfeeding women were enrolled in this study. Dietary pattern was assessed through a 72-hour dietary recall questionnaire (days 7 and 28 postpartum) and data were compared with Dietary Recommendation Values (DRV), and through the Adherence to Healthy Food Pyramid (HFP) questionnaire (day 28). Anthropometric parameters were evaluated by bioimpedance. Using factor analysis, nutritional dimensions were extracted, and linear regression models were used to analyze the association between anthropometric parameters and dimensions. Compared to the DRV, women showed insufficient energy, water, vitamin D, and potassium intake and excessive proteins, vitamins B1, B2, B3, B6, B12, and iron intake. We observed a moderate adherence to the HFP, with women being high in the fruits, vegetables, and oil categories, and low adherence to the physical activity, dairy products, and hydration categories. The nutritional dimension, including the HFP categories of physical activity, hydration, and animal protein intake together, was negatively associated with body weight (β = −3.7 ± 1.7; p-value = 0.047). In conclusion, during the first month postpartum, breastfeeding women exhibited several nutritional imbalances and poor physical activity negatively influencing anthropometric parameters. We propose a multidimensional approach to assess the nutritional status of breastfeeding women as a tool to detect specific deficiencies, allowing for personalized counseling.
Andrea Gila-Díaz; Nuria Díaz-Rullo Alcántara; Gloria Herranz Carrillo; Pratibha Singh; Silvia Arribas; David Ramiro-Cortijo. Multidimensional Approach to Assess Nutrition and Lifestyle in Breastfeeding Women during the First Month of Lactation. Nutrients 2021, 13, 1766 .
AMA StyleAndrea Gila-Díaz, Nuria Díaz-Rullo Alcántara, Gloria Herranz Carrillo, Pratibha Singh, Silvia Arribas, David Ramiro-Cortijo. Multidimensional Approach to Assess Nutrition and Lifestyle in Breastfeeding Women during the First Month of Lactation. Nutrients. 2021; 13 (6):1766.
Chicago/Turabian StyleAndrea Gila-Díaz; Nuria Díaz-Rullo Alcántara; Gloria Herranz Carrillo; Pratibha Singh; Silvia Arribas; David Ramiro-Cortijo. 2021. "Multidimensional Approach to Assess Nutrition and Lifestyle in Breastfeeding Women during the First Month of Lactation." Nutrients 13, no. 6: 1766.
Early detection of gestational complications is a priority in obstetrics. In our social context, this is linked to maternity age. Most studies are focused on biological factors. However, pregnancy is also influenced by social and psychological factors, which have not been deeply explored. We aimed to identify biopsychosocial risk and protective factors associated with the development of maternal and fetal complications. We enrolled 182 healthy pregnant women, and plasma melatonin and cortisol levels were measured in the first trimester by chemiluminescent immunoassays. At different time points along gestation, women answered several questionnaires (positive and negative affect schedule, hospital anxiety and depression scale, pregnancy concerns scale, life orientation test, resilience scale, life satisfaction scale and life–work conflicts scale). They were followed up until delivery and categorized as normal pregnancy, maternal or fetal complications. Maternal complications were associated with low melatonin (OR = 0.99 [0.98; 1.00]; p-value = 0.08) and life satisfaction (OR = 0.64 [0.41; 0.93]; p-value = 0.03) and fetal complications were associated with high cortisol (OR = 1.06 [1.02; 1.13]; p-value = 0.04), anxiety (OR = 2.21 [1.10; 4.55]; p-value = 0.03) and life–work conflicts (OR = 1.92 [1.04; 3.75]; p-value = 0.05). We conclude that psychological factors influence pregnancy outcomes in association with melatonin and cortisol alterations. High maternal melatonin and life satisfaction levels could be potential protective factors against the development of maternal complications during pregnancy. Low anxiety and cortisol levels and reduced work–life conflicts could prevent fetal complications.
David Ramiro-Cortijo; Maria de la Calle; Vanesa Benitez; Andrea Gila-Diaz; Bernardo Moreno-Jiménez; Silvia Arribas; Eva Garrosa. Maternal Psychological and Biological Factors Associated to Gestational Complications. Journal of Personalized Medicine 2021, 11, 183 .
AMA StyleDavid Ramiro-Cortijo, Maria de la Calle, Vanesa Benitez, Andrea Gila-Diaz, Bernardo Moreno-Jiménez, Silvia Arribas, Eva Garrosa. Maternal Psychological and Biological Factors Associated to Gestational Complications. Journal of Personalized Medicine. 2021; 11 (3):183.
Chicago/Turabian StyleDavid Ramiro-Cortijo; Maria de la Calle; Vanesa Benitez; Andrea Gila-Diaz; Bernardo Moreno-Jiménez; Silvia Arribas; Eva Garrosa. 2021. "Maternal Psychological and Biological Factors Associated to Gestational Complications." Journal of Personalized Medicine 11, no. 3: 183.
Cognitive maternal adaptation during pregnancy may influence biological variables, maternal psychological, and neonatal health. We hypothesized that pregnant women with numerous general resources and less negative emotions would have a better coping with a positive influence on neonatal birth weight and maternal psychological health. The study included 131 healthy pregnant women. A blood sample was obtained in the first trimester to assess biological variables (polyphenols, hematological and biochemical parameters). Psychological variables (negative affect, anxiety, optimism, resilience, family–work conflicts, pregnancy concerns, general resources, and life satisfaction) were evaluated at several time points along gestation, and birth weight was recorded. Hierarchical linear regression models were used to associate the above parameters with maternal psychological outcome at the end of gestation (depression, resilience, and optimism) and neonatal outcome (birth weight). Maternal depression was associated with leukocytes (β = 0.08 ± 0.03, p-value = 0.003), cholesterol (β = 0.01 ± 0.002, p-value = 0.026), and pregnancy concerns (β = 0.31 ± 0.09, p-value = 0.001). Maternal resilience was associated with leukocytes (β = −0.14 ± 0.09, p-value = 0.010) and life satisfaction (β = 0.82 ± 0.08, p-value = 0.001), and maternal optimism was associated with polyphenol levels (β = 0.002 ± 0.001, p-value = 0.018) and life satisfaction (β = 0.49 ± 0.04, p-value = 0.001). Birth weight was associated with maternal resilience (β = 370.2 ± 97.0, p-value = 0.001), red blood cells (β = 480.3 ± 144.4, p-value = 0.001), and life satisfaction (β = 423.3 ± 32.6, p-value = 0.001). We found associations between maternal psychological, blood variables, and birth weight and maternal depression. This study reveals the relevance of psychological health during pregnancy for maternal and neonatal outcome, and it emphasizes the need to consider it in preventive policies in the obstetric field.
David Ramiro-Cortijo; María de la Calle; Andrea Gila-Díaz; Bernardo Moreno-Jiménez; Maria Martin-Cabrejas; Silvia Arribas; Eva Garrosa. Maternal Resources, Pregnancy Concerns, and Biological Factors Associated to Birth Weight and Psychological Health. Journal of Clinical Medicine 2021, 10, 695 .
AMA StyleDavid Ramiro-Cortijo, María de la Calle, Andrea Gila-Díaz, Bernardo Moreno-Jiménez, Maria Martin-Cabrejas, Silvia Arribas, Eva Garrosa. Maternal Resources, Pregnancy Concerns, and Biological Factors Associated to Birth Weight and Psychological Health. Journal of Clinical Medicine. 2021; 10 (4):695.
Chicago/Turabian StyleDavid Ramiro-Cortijo; María de la Calle; Andrea Gila-Díaz; Bernardo Moreno-Jiménez; Maria Martin-Cabrejas; Silvia Arribas; Eva Garrosa. 2021. "Maternal Resources, Pregnancy Concerns, and Biological Factors Associated to Birth Weight and Psychological Health." Journal of Clinical Medicine 10, no. 4: 695.
Coffee pulp is a by-product generated during coffee processing, producing environmental pollution when discarded in rivers. The revalorization of coffee by-products is currently being studied due to their high potential as new value-added food ingredients. This work aims to explore the chemical composition and functional properties of coffee pulp and validate its safety for use as a novel food ingredient. Coffee pulp composition was assessed following the standard methods (AOAC). Physicochemical properties, total phenolic compounds (TPC), antioxidant capacity, hypoglycemic and hypolipidemic properties were determined using in vitro techniques. Acute and sub-chronic oral toxicity experiments were carried out following OECD Test Guidelines 452 and 408. Coffee pulp showed a high content of dietary fiber (51.2%), highlighting the insoluble fraction. Proteins (9.2%) and lipids (2.6%) were considered a min fraction. Coffee pulp presented high content of TPC (40.6 mg g−1), of which 29% were linked to DF, giving coffee pulp its antioxidant potential (102.3 mg Trolox eq g−1). The by-product showed good physicochemical properties. Coffee pulp reduced the absorption of cholesterol (84%) and bile salts (85%), inhibited pancreatic lipase (64%), and presented the capacity to diminish the diffusion of glucose (34%). The intake of coffee pulp did not cause significant lesions in vital organs. In conclusion, the coffee pulp could be used as a potential ingredient with beneficial health properties.
Silvia Cañas; Miguel Rebollo-Hernanz; Paz Cano-Muñoz; Yolanda Aguilera; Vanesa Benítez; Cheyenne Braojos; Andrea Gila-Díaz; Pilar Rodríguez-Rodríguez; Ignacio Monedo Cobeta; Ángel L. López de Pablo; Maria Del Carmen González; Silvia M. Arribas; Maria A. Martin-Cabrejas. Critical Evaluation of Coffee Pulp as an Innovative Antioxidant Dietary Fiber Ingredient: Nutritional Value, Functional Properties, and Acute and Sub-Chronic Toxicity. Proceedings 2020, 70, 65 .
AMA StyleSilvia Cañas, Miguel Rebollo-Hernanz, Paz Cano-Muñoz, Yolanda Aguilera, Vanesa Benítez, Cheyenne Braojos, Andrea Gila-Díaz, Pilar Rodríguez-Rodríguez, Ignacio Monedo Cobeta, Ángel L. López de Pablo, Maria Del Carmen González, Silvia M. Arribas, Maria A. Martin-Cabrejas. Critical Evaluation of Coffee Pulp as an Innovative Antioxidant Dietary Fiber Ingredient: Nutritional Value, Functional Properties, and Acute and Sub-Chronic Toxicity. Proceedings. 2020; 70 (1):65.
Chicago/Turabian StyleSilvia Cañas; Miguel Rebollo-Hernanz; Paz Cano-Muñoz; Yolanda Aguilera; Vanesa Benítez; Cheyenne Braojos; Andrea Gila-Díaz; Pilar Rodríguez-Rodríguez; Ignacio Monedo Cobeta; Ángel L. López de Pablo; Maria Del Carmen González; Silvia M. Arribas; Maria A. Martin-Cabrejas. 2020. "Critical Evaluation of Coffee Pulp as an Innovative Antioxidant Dietary Fiber Ingredient: Nutritional Value, Functional Properties, and Acute and Sub-Chronic Toxicity." Proceedings 70, no. 1: 65.
Early breastfeeding cessation is a major public health problem. Several factors can affect breastfeeding pattern, and psychological aspects have been poorly explored. We hypothesize that psychological factors and breastfeeding pattern have a relationship. We have assessed in mothers during the first six months of lactation if breastfeeding pattern is associated with maternal stress, postpartum depression, and dispositional optimism, and if these psychological factors play a role on breastfeeding adherence. In total, 711 women participated, answering online the following questionnaires: sociodemographic, perceived stress scale, Edinburgh postpartum depression scale, life orientation test, and breastfeeding adherence score. Women were categorized according to infant feeding practices as exclusive breastfeeding (EBF) or mixed breastfeeding (MBF). The EBF group had a lower score of perceived stress compared to those giving MBF (first month: EBF = 1.5 [1.1; 1.9], MBF = 1.8 [1.5; 2.0]; p-Value = 0.030; third month: EBF = 1.6 [1.2; 2.0], MBF = 1.8 [1.5; 2.4]; p-Value = 0.038) and also had a lower score of postpartum depression (third month: EBF = 8.0 [6.0; 11.0], MBF = 11.0 [9.0; 15.0]; p-Value = 0.001). The breastfeeding adherence score showed a positive correlation with maternal perceived stress (first month: ρ = 0.27; p-Value = 0.018), and postpartum depression (third month: ρ = 0.30; p-Value < 0.001), and a negative correlation with maternal dispositional optimism (second month: ρ = −0.20; p-Value = 0.028). MBF was positively associated with breastfeeding adherence score (odd ratio (OR) = 1.4 [1.2–1.6]; p-Value < 0.001) and with postpartum depression (OR = 1.1 [1.0; 1.1]; p-Value = 0.020). In the third month of breastfeeding, women with MBF exhibited higher perceive stress and postpartum depression compared to those with EBF and no difference in dispositional optimism. The maternal psychological aspects are associated with breastfeeding pattern. Evaluation of maternal psychological concerns and providing support to lactating mothers may help improving breastfeeding adherence.
Andrea Gila-Díaz; Gloria Herranz Carrillo; Ángel Luis López De Pablo; Silvia M. Arribas; David Ramiro-Cortijo. Association between Maternal Postpartum Depression, Stress, Optimism, and Breastfeeding Pattern in the First Six Months. International Journal of Environmental Research and Public Health 2020, 17, 7153 .
AMA StyleAndrea Gila-Díaz, Gloria Herranz Carrillo, Ángel Luis López De Pablo, Silvia M. Arribas, David Ramiro-Cortijo. Association between Maternal Postpartum Depression, Stress, Optimism, and Breastfeeding Pattern in the First Six Months. International Journal of Environmental Research and Public Health. 2020; 17 (19):7153.
Chicago/Turabian StyleAndrea Gila-Díaz; Gloria Herranz Carrillo; Ángel Luis López De Pablo; Silvia M. Arribas; David Ramiro-Cortijo. 2020. "Association between Maternal Postpartum Depression, Stress, Optimism, and Breastfeeding Pattern in the First Six Months." International Journal of Environmental Research and Public Health 17, no. 19: 7153.
Breast milk (BM) is beneficial due to its content in a wide range of different antioxidants, particularly relevant for preterm infants, who are at higher risk of oxidative stress. We hypothesize that BM antioxidants are adapted to gestational age and are negatively influenced by maternal age. Fifty breastfeeding women from two hospitals (Madrid, Spain) provided BM samples at days 7, 14 and 28 of lactation to assess total antioxidant capacity (ABTS), thiol groups, reduced glutathione (GSH), superoxide dismutase (SOD) and catalase activities, lipid peroxidation (malondialdehyde, MDA + 4-Hydroxy-Trans-2-Nonenal, HNE), protein oxidation (carbonyl groups) (spectrophotometry) and melatonin (ELISA). Mixed random-effects linear regression models were used to study the influence of maternal and gestational ages on BM antioxidants, adjusted by days of lactation. Regression models evidenced a negative association between maternal age and BM melatonin levels (β = −7.4 ± 2.5; p-value = 0.005); and a negative association between gestational age and BM total antioxidant capacity (β = −0.008 ± 0.003; p-value = 0.006), SOD activity (β = −0.002 ± 0.001; p-value = 0.043) and protein oxidation (β = −0.22 ± 0.07; p-value = 0.001). In conclusion, BM antioxidants are adapted to gestational age providing higher levels to infants with lower degree of maturation; maternal ageing has a negative influence on melatonin, a key antioxidant hormone.
Andrea Gila-Díaz; Gloria Herranz Carrillo; Silvia Cañas; Miguel Saenz De Pipaón; José Antonio Martínez-Orgado; Pilar Rodríguez-Rodríguez; Ángel Luis López De Pablo; María A. Martin-Cabrejas; David Ramiro-Cortijo; Silvia M. Arribas. Influence of Maternal Age and Gestational Age on Breast Milk Antioxidants During the First Month of Lactation. Nutrients 2020, 12, 2569 .
AMA StyleAndrea Gila-Díaz, Gloria Herranz Carrillo, Silvia Cañas, Miguel Saenz De Pipaón, José Antonio Martínez-Orgado, Pilar Rodríguez-Rodríguez, Ángel Luis López De Pablo, María A. Martin-Cabrejas, David Ramiro-Cortijo, Silvia M. Arribas. Influence of Maternal Age and Gestational Age on Breast Milk Antioxidants During the First Month of Lactation. Nutrients. 2020; 12 (9):2569.
Chicago/Turabian StyleAndrea Gila-Díaz; Gloria Herranz Carrillo; Silvia Cañas; Miguel Saenz De Pipaón; José Antonio Martínez-Orgado; Pilar Rodríguez-Rodríguez; Ángel Luis López De Pablo; María A. Martin-Cabrejas; David Ramiro-Cortijo; Silvia M. Arribas. 2020. "Influence of Maternal Age and Gestational Age on Breast Milk Antioxidants During the First Month of Lactation." Nutrients 12, no. 9: 2569.
We aimed to design and validate a new questionnaire of adherence to healthy food pyramid (HFP) (AP-Q), to improve previous instruments. The questionnaire was self-administered and included 28 questions from 10 categories (physical activity, health habits, hydration, grains, fruits, vegetables, oil type, dairy products, animal proteins, and snacks). A population of 130 Spanish adults answered it, obtaining scores from each category and a global score of HFP adherence (AP-Q score). Validation was performed through principal components analysis (PCA) and internal consistency by Cronbach’s alpha. AP-Q was also externally validated with Kidmed-test, answered by 45 individuals from the cohort. The global AP-Q score was 5.1 ± 1.3, with an internal consistency of 64%. The PCA analysis extracted seven principal components, which explained 68.5% of the variance. The global AP-Q score was positively associated with Kidmed-test score. Our data suggest that AP-Q is a complete and robust questionnaire to assess HFP adherence, with several advantages: easy to complete, cost-effective, timesaving and has the competency to assess, besides diet, several features affecting health status, lacking in other instruments. We suggest that AP-Q could be useful in epidemiological research, although it requires additional calibration to analyze its reproducibility and validation in other populations.
Andrea Gila-Díaz; Silvia M. Arribas; Ángel Luis López De Pablo; Ma Rosario López-Giménez; Sophida Phuthong; David Ramiro-Cortijo. Development and Validation of a Questionnaire to Assess Adherence to the Healthy Food Pyramid in Spanish Adults. Nutrients 2020, 12, 1656 .
AMA StyleAndrea Gila-Díaz, Silvia M. Arribas, Ángel Luis López De Pablo, Ma Rosario López-Giménez, Sophida Phuthong, David Ramiro-Cortijo. Development and Validation of a Questionnaire to Assess Adherence to the Healthy Food Pyramid in Spanish Adults. Nutrients. 2020; 12 (6):1656.
Chicago/Turabian StyleAndrea Gila-Díaz; Silvia M. Arribas; Ángel Luis López De Pablo; Ma Rosario López-Giménez; Sophida Phuthong; David Ramiro-Cortijo. 2020. "Development and Validation of a Questionnaire to Assess Adherence to the Healthy Food Pyramid in Spanish Adults." Nutrients 12, no. 6: 1656.
Preterm birth is an increasing worldwide problem. Prematurity is the second most common cause of death in children under 5 years of age. It is associated with a higher risk of several pathologies in the perinatal period and adulthood. Maternal milk, a complex fluid with several bioactive factors, is the best option for the newborn. Its dynamic composition is influenced by diverse factors such as maternal age, lactation period, and health status. The aim of the present review is to summarize the current knowledge regarding some bioactive factors present in breastmilk, namely antioxidants, growth factors, adipokines, and cytokines, paying specific attention to prematurity. The revised literature reveals that the highest levels of these bioactive factors are found in the colostrum and they decrease along the lactation period; bioactive factors are found in higher levels in preterm as compared to full-term milk, they are lacking in formula milk, and decreased in donated milk. However, there are still some gaps and inconclusive data, and further research in this field is needed. Given the fact that many preterm mothers are unable to complete breastfeeding, new information could be important to develop infant supplements that best match preterm human milk.
Andrea Gila-Diaz; Silvia M. Arribas; Alba Algara; María A. Martín-Cabrejas; Ángel Luis López De Pablo; Miguel Sáenz De Pipaón; David Ramiro-Cortijo. A Review of Bioactive Factors in Human Breastmilk: A Focus on Prematurity. Nutrients 2019, 11, 1307 .
AMA StyleAndrea Gila-Diaz, Silvia M. Arribas, Alba Algara, María A. Martín-Cabrejas, Ángel Luis López De Pablo, Miguel Sáenz De Pipaón, David Ramiro-Cortijo. A Review of Bioactive Factors in Human Breastmilk: A Focus on Prematurity. Nutrients. 2019; 11 (6):1307.
Chicago/Turabian StyleAndrea Gila-Diaz; Silvia M. Arribas; Alba Algara; María A. Martín-Cabrejas; Ángel Luis López De Pablo; Miguel Sáenz De Pipaón; David Ramiro-Cortijo. 2019. "A Review of Bioactive Factors in Human Breastmilk: A Focus on Prematurity." Nutrients 11, no. 6: 1307.