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The corona virus pandemic undoubtedly demonstrates the growing need for research in medical science. However, with the decline in physician scientists world-wide, innovative ways are needed to engender interest in research among medical students and young doctors to replenish the stock of physician investigators. One way of doing this is to create compulsory and elective projects for them. We describe research internships created for medical students at the Noguchi Memorial Institute for Medical Research to expose them to the rudiments of biomedical research and proposal development. We also describe research internships for doctors waiting for house job postings or keen to do research who needed mentorship. Though the response has been positive, the full impact will be realized with time. The recognition that training should be backed with a supportive environment, mentorship and clear career paths for physician scientists is also mentioned.
Edem Ma Tette; Ben A Gyan; Kwadwo A Koram. Perspectives on Research Internships for Medical Students and Young Doctors in Ghana: An Opportunity to Replenish the Stock of Physician Investigators? Advances in Medical Education and Practice 2020, ume 11, 473 -478.
AMA StyleEdem Ma Tette, Ben A Gyan, Kwadwo A Koram. Perspectives on Research Internships for Medical Students and Young Doctors in Ghana: An Opportunity to Replenish the Stock of Physician Investigators? Advances in Medical Education and Practice. 2020; ume 11 ():473-478.
Chicago/Turabian StyleEdem Ma Tette; Ben A Gyan; Kwadwo A Koram. 2020. "Perspectives on Research Internships for Medical Students and Young Doctors in Ghana: An Opportunity to Replenish the Stock of Physician Investigators?" Advances in Medical Education and Practice ume 11, no. : 473-478.
High global neonatal deaths have triggered efforts to improve facility-based care. However, the outcomes achievable at different levels of care are unclear. This study compared morbidity and mortality patterns of newborns admitted to a regional and a district hospital in Ghana to determine outcome, risk and modifiable factors associated with mortality. This study compared morbidity and mortality patterns of newborns admitted to a regional and a district hospital in Ghana to determine outcome, risk and modifiable factors associated with mortality A cross-sectional study involving a records-review over one year at the Upper West Regional Hospital, and three years at St Joseph’s District Hospital, Jirapa was carried out. Age, sex, gestational age, weight, duration of admission, diagnosis, among others were examined. The data were analysed and statistical inference made. Altogether, 2004 newborns were examined, comprising 1,241(62%) from St Joseph’s District Hospital and 763(38%) from Upper West Regional Hospital. The proportion of neonatal deaths was similar, 8.94% (St Joseph’s District Hospital) and 8.91% (Upper West Regional Hospital). Prematurity, neonatal sepsis, birth asphyxia, low birth weight, neonatal jaundice and pneumonia contributed the most to mortality and suspected infections including malaria accounted for almost half (45.5%). Mortality was significantly associated with duration of stay of 48 hours, being premature, and being younger than 3 days. Majority of the mortality among the neonates admitted was due to preventable causes. Better stabilization and further studies on the epidemiology of sepsis, prematurity, low birth weight, including the contribution of malaria to these and outcome of transferred neonates are needed.
Edem M. A. Tette; Edmund T. Nartey; Benjamin D. Nuertey; Emmanuel A. Azusong; Dominic Akaateba; Judith Yirifere; Augustine Alandu; Nana Ayegua Hagan Seneadza; Naa Barnabas Gandau; Lorna A. Renner. The pattern of neonatal admissions and mortality at a regional and district hospital in the Upper West Region of Ghana; a cross sectional study. PLOS ONE 2020, 15, e0232406 .
AMA StyleEdem M. A. Tette, Edmund T. Nartey, Benjamin D. Nuertey, Emmanuel A. Azusong, Dominic Akaateba, Judith Yirifere, Augustine Alandu, Nana Ayegua Hagan Seneadza, Naa Barnabas Gandau, Lorna A. Renner. The pattern of neonatal admissions and mortality at a regional and district hospital in the Upper West Region of Ghana; a cross sectional study. PLOS ONE. 2020; 15 (5):e0232406.
Chicago/Turabian StyleEdem M. A. Tette; Edmund T. Nartey; Benjamin D. Nuertey; Emmanuel A. Azusong; Dominic Akaateba; Judith Yirifere; Augustine Alandu; Nana Ayegua Hagan Seneadza; Naa Barnabas Gandau; Lorna A. Renner. 2020. "The pattern of neonatal admissions and mortality at a regional and district hospital in the Upper West Region of Ghana; a cross sectional study." PLOS ONE 15, no. 5: e0232406.
The aim of this study was to investigate S. aureus carriage among children with sickle cell disease (SCD), including the prevalence, risk factors, and antibiotic resistance. The study was cross-sectional, and involved 120 children with SCD recruited at the Princess Marie Louise Children’s Hospital (PML) in Accra and 100 apparently healthy children from environs of the hospital. Nasal swab samples were collected from the study participants and cultured for bacteria. Confirmation of S. aureus and methicillin-resistant Staphylococcus aureus (MRSA) isolates were done using the tube coagulase test and mecA polymerase chain reaction, respectively. All the S. aureus isolates were tested against standard antimicrobial agents using the Kirby-Bauer method. A structured questionnaire was used to obtain the socio-demographic and clinical data of the study participants. Binary logistic regression was used to identify determinants of S. aureus and MRSA carriage among the study participants. The nasal carriage prevalence of S. aureus was 33.3% (n = 40) and 10% (n = 10) among the participants of the SCD and control groups, respectively. As regards MRSA nasal carriage prevalence, the respective values were 3.33% (n = 4) and 0.00% (n = 0). SCD was significantly associated with S. aureus colonization (p < 0.0001, OR = 4.045), but not MRSA colonization (p = 0.128). In the SCD group, the significant predictors of S. aureus carriage were increasing age (p = 0.003; OR = 1.275) and living in self-contained apartments (p = 0.033; OR = 3.632), whereas male gender (p = 0.018; OR = 0.344) and the practice of self-medication (p = 0.039; OR = 0.233) were protective of S. aureus carriage. In the control group, a history of hospitalization in the past year was a risk factor for the carriage of S. aureus (p = 0.048; OR = 14.333). Among the participants of the SCD and control groups, respectively, the resistance prevalence recorded by S. aureus against the various antibiotics investigated were penicillin (100% each), cotrimoxazole (27.5% vs. 20%), tetracycline (25% vs. 50%), rifampicin (82.5% vs. 50%), erythromycin (30% vs. 20%), clindamycin (32.5% vs. 50%), gentamicin (7.5% vs. 20%), cefoxitin (27.5% vs. 20%), linezolid (30% vs. 40%), and fusidic acid (95% vs. 80%). The proportion of S. aureus isolates that were multidrug resistant (MDR) was 92.5% (37/40) in the SCD group and 100% (10/10) in the control group.
Vera A. Appiah; George A. Pesewu; Fleischer C. N. Kotey; Alahaman Nana Boakye; Samuel Duodu; Edem M. A. Tette; Mame Y. Nyarko; Eric S. Donkor. Staphylococcus aureus Nasal Colonization among Children with Sickle Cell Disease at the Children’s Hospital, Accra: Prevalence, Risk Factors, and Antibiotic Resistance. Pathogens 2020, 9, 329 .
AMA StyleVera A. Appiah, George A. Pesewu, Fleischer C. N. Kotey, Alahaman Nana Boakye, Samuel Duodu, Edem M. A. Tette, Mame Y. Nyarko, Eric S. Donkor. Staphylococcus aureus Nasal Colonization among Children with Sickle Cell Disease at the Children’s Hospital, Accra: Prevalence, Risk Factors, and Antibiotic Resistance. Pathogens. 2020; 9 (5):329.
Chicago/Turabian StyleVera A. Appiah; George A. Pesewu; Fleischer C. N. Kotey; Alahaman Nana Boakye; Samuel Duodu; Edem M. A. Tette; Mame Y. Nyarko; Eric S. Donkor. 2020. "Staphylococcus aureus Nasal Colonization among Children with Sickle Cell Disease at the Children’s Hospital, Accra: Prevalence, Risk Factors, and Antibiotic Resistance." Pathogens 9, no. 5: 329.
Optimum care of sick neonates often involves transporting them across different levels of care. Since their condition may deteriorate over time, attention needs to be paid to travel distances and how they are transferred. We examined the mode of transport, distances travelled, condition on arrival and outcome of outborn neonates admitted to a district and a regional hospital in Ghana using a cross-sectional study involving caregivers of neonates admitted to these hospitals. Information on referral characteristics and outcome were obtained from questionnaires and the child’s case notes. Overall, 153 caregivers and babies were studied. Twelve deaths, 7.8%, occurred. Neonates who died spent a median duration of 120 min at the first health facility they visited compared with 30 min spent by survivors; they travelled mostly by public buses, (41.7%), compared with 36.0% of survivors who used taxis. Majority of survivors, 70.2%, had normal heart rates on arrival compared with only 41.7% of neonates who died; hypothermia was present in 66.7% compared with 47.6% of survivors. These findings indicate that the logistics for neonatal transport were inadequate to keep the neonates stable during the transfer process, thus many of them were compromised especially those who died. Further studies are warranted.
Edem M. A. Tette; Benjamin D. Nuertey; Dominic Akaateba; Naa Barnabas Gandau. The Transport and Outcome of Sick Outborn Neonates Admitted to a Regional and District Hospital in the Upper West Region of Ghana: A Cross-Sectional Study. Children 2020, 7, 22 .
AMA StyleEdem M. A. Tette, Benjamin D. Nuertey, Dominic Akaateba, Naa Barnabas Gandau. The Transport and Outcome of Sick Outborn Neonates Admitted to a Regional and District Hospital in the Upper West Region of Ghana: A Cross-Sectional Study. Children. 2020; 7 (3):22.
Chicago/Turabian StyleEdem M. A. Tette; Benjamin D. Nuertey; Dominic Akaateba; Naa Barnabas Gandau. 2020. "The Transport and Outcome of Sick Outborn Neonates Admitted to a Regional and District Hospital in the Upper West Region of Ghana: A Cross-Sectional Study." Children 7, no. 3: 22.
Neonatal mortality is the major contributor to under-five mortality rates in many low and middle income countries. We examined the health practices, care-seeking behavior, and referral of sick outborn neonates to a district and regional hospital in the Upper West Region of Ghana. The study was a cross-sectional study conducted over an eight (8) month period in 2018. Data were obtained from caregiver interviews and case notes. Altogether, 153 outborn neonates were examined. Inappropriate practices including the use of enemas, cord care with cow dung, and herbal baths were found. Three babies treated this way died. The majority of caregivers sought care at a health facility. However, 67 (44%) sought care only after their babies were ill for ≥7 days, suggesting the influence of a period of confinement on health seeking. More than half, 94 (61.4%), of the facilities visited referred patients to destination hospitals without giving any treatment. Delayed care-seeking was associated with a low birth weight, using home remedies, and a maternal age of ≥30 years. Altogether, 12 neonates (7.8%) died, consisting of three males and nine females (p = 0.018). Socio-cultural factors strongly influence health seeking behavior and the health outcome of neonates in this setting. There appeared to be a limited repertoire of interventions for treating neonatal disease in primary care.
Edem Tette; Benjamin Nuertey; Emmanuel Azusong; Naa Gandau. The Profile, Health Seeking Behavior, Referral Patterns, and Outcome of Outborn Neonates Admitted to a District and Regional Hospital in the Upper West Region of Ghana: A Cross-Sectional Study. Children 2020, 7, 15 .
AMA StyleEdem Tette, Benjamin Nuertey, Emmanuel Azusong, Naa Gandau. The Profile, Health Seeking Behavior, Referral Patterns, and Outcome of Outborn Neonates Admitted to a District and Regional Hospital in the Upper West Region of Ghana: A Cross-Sectional Study. Children. 2020; 7 (2):15.
Chicago/Turabian StyleEdem Tette; Benjamin Nuertey; Emmanuel Azusong; Naa Gandau. 2020. "The Profile, Health Seeking Behavior, Referral Patterns, and Outcome of Outborn Neonates Admitted to a District and Regional Hospital in the Upper West Region of Ghana: A Cross-Sectional Study." Children 7, no. 2: 15.