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Ranjit Philip; Neil Tailor; Jason N. Johnson; Leah Apalodimas; Jorden Cunningham; Judy Hoy; B. Rush Waller Iii; Shyam Sathanandam. Single-Center Experience of 100 Consecutive Percutaneous Patent Ductus Arteriosus Closures in Infants ≤1000 Grams. Circulation: Cardiovascular Interventions 2021, 14, e010600 .
AMA StyleRanjit Philip, Neil Tailor, Jason N. Johnson, Leah Apalodimas, Jorden Cunningham, Judy Hoy, B. Rush Waller Iii, Shyam Sathanandam. Single-Center Experience of 100 Consecutive Percutaneous Patent Ductus Arteriosus Closures in Infants ≤1000 Grams. Circulation: Cardiovascular Interventions. 2021; 14 (6):e010600.
Chicago/Turabian StyleRanjit Philip; Neil Tailor; Jason N. Johnson; Leah Apalodimas; Jorden Cunningham; Judy Hoy; B. Rush Waller Iii; Shyam Sathanandam. 2021. "Single-Center Experience of 100 Consecutive Percutaneous Patent Ductus Arteriosus Closures in Infants ≤1000 Grams." Circulation: Cardiovascular Interventions 14, no. 6: e010600.
Benjamin S. Hendrickson; Ryan E. Stephens; James V. Chang; Jacob M. Amburn; Lindsey L. Pierotti; Jessica L. Johnson; John C. Hyden; Jason N. Johnson; Ranjit R. Philip. Cardiovascular Evaluation After COVID-19 in 137 Collegiate Athletes: Results of an Algorithm-Guided Screening. Circulation 2021, 143, 1926 -1928.
AMA StyleBenjamin S. Hendrickson, Ryan E. Stephens, James V. Chang, Jacob M. Amburn, Lindsey L. Pierotti, Jessica L. Johnson, John C. Hyden, Jason N. Johnson, Ranjit R. Philip. Cardiovascular Evaluation After COVID-19 in 137 Collegiate Athletes: Results of an Algorithm-Guided Screening. Circulation. 2021; 143 (19):1926-1928.
Chicago/Turabian StyleBenjamin S. Hendrickson; Ryan E. Stephens; James V. Chang; Jacob M. Amburn; Lindsey L. Pierotti; Jessica L. Johnson; John C. Hyden; Jason N. Johnson; Ranjit R. Philip. 2021. "Cardiovascular Evaluation After COVID-19 in 137 Collegiate Athletes: Results of an Algorithm-Guided Screening." Circulation 143, no. 19: 1926-1928.
There continues to be a reluctance to close the patent ductus arteriosus (PDA) in premature infants. The debate on whether the short-term outcomes translate to a difference in long-term benefits remains. This article intends to review the pulmonary vasculature changes that can occur with a chronic hemodynamically significant PDA in a preterm infant. It also explains the rationale and decision-making involved in a diagnostic cardiac catheterization and transcatheter PDA closure in these preterm infants.
Ranjit Philip; Vineet Lamba; Ajay Talati; Shyam Sathanandam. Pulmonary Hypertension with Prolonged Patency of the Ductus Arteriosus in Preterm Infants. Children 2020, 7, 139 .
AMA StyleRanjit Philip, Vineet Lamba, Ajay Talati, Shyam Sathanandam. Pulmonary Hypertension with Prolonged Patency of the Ductus Arteriosus in Preterm Infants. Children. 2020; 7 (9):139.
Chicago/Turabian StyleRanjit Philip; Vineet Lamba; Ajay Talati; Shyam Sathanandam. 2020. "Pulmonary Hypertension with Prolonged Patency of the Ductus Arteriosus in Preterm Infants." Children 7, no. 9: 139.
Ranjit Philip; B. Rush Waller; Sandeep Chilakala; Brittany Graham; Nathan Stecchi; Leah Apalodimas; Jorden Cunningham; Kristen Washington; Shyam Sathanandam. Hemodynamic and clinical consequences of early versus delayed closure of patent ductus arteriosus in extremely low birth weight infants. Journal of Perinatology 2020, 41, 100 -108.
AMA StyleRanjit Philip, B. Rush Waller, Sandeep Chilakala, Brittany Graham, Nathan Stecchi, Leah Apalodimas, Jorden Cunningham, Kristen Washington, Shyam Sathanandam. Hemodynamic and clinical consequences of early versus delayed closure of patent ductus arteriosus in extremely low birth weight infants. Journal of Perinatology. 2020; 41 (1):100-108.
Chicago/Turabian StyleRanjit Philip; B. Rush Waller; Sandeep Chilakala; Brittany Graham; Nathan Stecchi; Leah Apalodimas; Jorden Cunningham; Kristen Washington; Shyam Sathanandam. 2020. "Hemodynamic and clinical consequences of early versus delayed closure of patent ductus arteriosus in extremely low birth weight infants." Journal of Perinatology 41, no. 1: 100-108.
Objective The objective of this article is to describe a live case transmission of transcatheter closure of a patent ductus arteriosus (PDA) in an extremely low birth weight (ELBW) infant during the first International PDA Symposium conducted in Memphis, Tennessee. Setting A multidisciplinary team approach including audiovisual specialists, information technology specialists, physicians, nurses, and other health care specialists was required to perform the transcatheter PDA closure (TCPC) in an ELBW infant at LeBonheur Children’s Hospital and the procedure was broadcast live to the attendees at the International PDA Symposium allowing for a two‐way audiovisual discussion during the procedure. Patient The patient was a 14 days old 24‐week premature ELBW infant, who weighed 700 g at the time of the procedure. The patient was requiring mechanical ventilation secondary to pulmonary hemorrhage. The PDA measured 4 mm in diameter and 12 mm in length. Interventions TCPC was performed safely without any procedural complications using a specialized minimally invasive technique. Outcome Measures The patient was weaned off the ventilator in < 7 days after the procedure. The child was discharged 9 weeks after the procedure (35 weeks’ corrected gestation) weighing 2.2 kg, on full oral feeds and no supplemental oxygen. Results The successful TCPC allowed for this child to have an uneventful hospital course. The case also highlights the technical nuances involved in setting up the live transmission. Conclusions This case demonstrated to the audience in the International PDA Symposium the feasibility and safety of performing TCPC in an ELBW infant. Live cases are useful in exhibiting the nuances involved in any new technique and allows for best learning experience.
Shyam Sathanandam; Ashley Gianinni; Eric Sefton; Kaitlyn Greer; Nathan Stecchi; Kimberly Allen; Ranjit Philip; B. Rush Waller. Live broadcast of transcatheter PDA closure in a 700 grams ELBW infant during the International PDA Symposium. Congenital Heart Disease 2019, 14, 85 -89.
AMA StyleShyam Sathanandam, Ashley Gianinni, Eric Sefton, Kaitlyn Greer, Nathan Stecchi, Kimberly Allen, Ranjit Philip, B. Rush Waller. Live broadcast of transcatheter PDA closure in a 700 grams ELBW infant during the International PDA Symposium. Congenital Heart Disease. 2019; 14 (1):85-89.
Chicago/Turabian StyleShyam Sathanandam; Ashley Gianinni; Eric Sefton; Kaitlyn Greer; Nathan Stecchi; Kimberly Allen; Ranjit Philip; B. Rush Waller. 2019. "Live broadcast of transcatheter PDA closure in a 700 grams ELBW infant during the International PDA Symposium." Congenital Heart Disease 14, no. 1: 85-89.
The hemodynamic effects of a patent ductus arteriosus (PDA) are well known including systemic hypoperfusion and volume overload on the left ventricle. This article aims to provide a review of the long‐standing effect of a hemodynamically significant PDA on the pulmonary vasculature and the role of cardiac catheterization in preterm infants with a PDA and pulmonary hypertension.
Ranjit Philip; Jason Nathaniel Johnson; Ronak Naik; Dai Kimura; Umar Boston; Sandeep Chilakala; Benjamin Hendrickson; Benjamin Rush Waller; Shyam Sathanandam. Effect of patent ductus arteriosus on pulmonary vascular disease. Congenital Heart Disease 2019, 14, 37 -41.
AMA StyleRanjit Philip, Jason Nathaniel Johnson, Ronak Naik, Dai Kimura, Umar Boston, Sandeep Chilakala, Benjamin Hendrickson, Benjamin Rush Waller, Shyam Sathanandam. Effect of patent ductus arteriosus on pulmonary vascular disease. Congenital Heart Disease. 2019; 14 (1):37-41.
Chicago/Turabian StyleRanjit Philip; Jason Nathaniel Johnson; Ronak Naik; Dai Kimura; Umar Boston; Sandeep Chilakala; Benjamin Hendrickson; Benjamin Rush Waller; Shyam Sathanandam. 2019. "Effect of patent ductus arteriosus on pulmonary vascular disease." Congenital Heart Disease 14, no. 1: 37-41.
There continues to be controversy on the long‐term effects of a patent ductus arteriosus (PDA) and its management. However, the hemodynamic effects of a large PDA in a preterm infant are well known. This article aims to provide insight into the adaptive changes and remodeling effects of a PDA on the myocardium in preterm infants.
Ranjit Philip; Jeffrey A. Towbin; Shyam Sathanandam; Jason Goldberg; Thomas Yohannan; Nithya Swaminathan; Jason Nathaniel Johnson. Effect of patent ductus arteriosus on the heart in preterm infants. Congenital Heart Disease 2019, 14, 33 -36.
AMA StyleRanjit Philip, Jeffrey A. Towbin, Shyam Sathanandam, Jason Goldberg, Thomas Yohannan, Nithya Swaminathan, Jason Nathaniel Johnson. Effect of patent ductus arteriosus on the heart in preterm infants. Congenital Heart Disease. 2019; 14 (1):33-36.
Chicago/Turabian StyleRanjit Philip; Jeffrey A. Towbin; Shyam Sathanandam; Jason Goldberg; Thomas Yohannan; Nithya Swaminathan; Jason Nathaniel Johnson. 2019. "Effect of patent ductus arteriosus on the heart in preterm infants." Congenital Heart Disease 14, no. 1: 33-36.
Objective Advancements in transcatheter technology have now made it possible to safely close patent ductus arteriosus (PDA) in extremely low birth weight (ELBW) infants. The objective of this article is to describe our technique for transcatheter PDA closure (TCPC) in ELBW infants. Design The techniques employed are very specific to this population and are drastically different when compared to the procedure performed in patients weighing >5 kg. Setting A multidisciplinary team approach should be taken to evaluate and manage ELBW infants in order to achieve success. It is important that specific techniques with venous‐only approach outlined in this article be followed to achieve optimal results with low risk of complications. Patients To date, in Memphis, 55 ELBW infants have had successful TCPC at a weight of ≤1000 g with minimal procedure‐related complications. Interventions It is important that specific techniques with venous‐only approach outlined in this article be followed to achieve optimal results with low risk of complications. Outcome measures This procedure entails a steep learning curve and should be limited to specialized centers with expertise in these thanscatheter procedures. Results There has been 100% procedural success of performing TCPC in children ≤1000 g. There have been only two procedure‐related complications which happened to the first two patients, ≤1000 g, that we performed TCPC on. Conclusions It is feasible and probably safe to perform TCPC in children ≤1000 g. The techniques described in this article represent our institutional experience and have helped us improve clinical outcomes in ELBW infants.
Shyam Sathanandam; Hitesh Agrawal; Sandeep Chilakala; Jason Johnson; Kimberly Allen Rn; Christopher Knott-Craig; B. Rush Waller; Ranjit Philip. Can transcatheter PDA closure be performed in neonates ≤1000 grams? The Memphis experience. Congenital Heart Disease 2019, 14, 79 -84.
AMA StyleShyam Sathanandam, Hitesh Agrawal, Sandeep Chilakala, Jason Johnson, Kimberly Allen Rn, Christopher Knott-Craig, B. Rush Waller, Ranjit Philip. Can transcatheter PDA closure be performed in neonates ≤1000 grams? The Memphis experience. Congenital Heart Disease. 2019; 14 (1):79-84.
Chicago/Turabian StyleShyam Sathanandam; Hitesh Agrawal; Sandeep Chilakala; Jason Johnson; Kimberly Allen Rn; Christopher Knott-Craig; B. Rush Waller; Ranjit Philip. 2019. "Can transcatheter PDA closure be performed in neonates ≤1000 grams? The Memphis experience." Congenital Heart Disease 14, no. 1: 79-84.
Echocardiographic imaging provides real‐time guidance during transcatheter patent ductus arteriosus (PDA) closure in extremely low birth weight (ELBW) infants. Transthoracic echocardiogram provides detailed assessment of the PDA and surrounding structures prior to, during, and after transcatheter closure. This article aims to review the different echocardiographic techniques and concepts utilized during transcatheter PDA closure in ELBW infants.
Jason Nathaniel Johnson; Shyam Sathanandam; Ronak Naik; Ranjit Philip. Echocardiographic guidance for transcatheter patent ductus arteriosus closure in extremely low birth weight infants. Congenital Heart Disease 2019, 14, 74 -78.
AMA StyleJason Nathaniel Johnson, Shyam Sathanandam, Ronak Naik, Ranjit Philip. Echocardiographic guidance for transcatheter patent ductus arteriosus closure in extremely low birth weight infants. Congenital Heart Disease. 2019; 14 (1):74-78.
Chicago/Turabian StyleJason Nathaniel Johnson; Shyam Sathanandam; Ronak Naik; Ranjit Philip. 2019. "Echocardiographic guidance for transcatheter patent ductus arteriosus closure in extremely low birth weight infants." Congenital Heart Disease 14, no. 1: 74-78.
Objectives Patent ductus arteriosus (PDA) is a common finding in preterm infants. A hemodynamically significant PDA may require intervention for closure. This article aims to describe a transcatheter PDA closure (TCPC) program for preterm infants and the components of a comprehensive outpatient follow‐up strategy. Setting A multidisciplinary team approach including neonatology, cardiology, anesthesiology, medical transport team, pulmonology, cardiac surgery, neurodevelopmental specialist, nutrition, speech therapy, social work, research collaborators, and other health care specialists is integral to the dedicated care and promotion of wellness of extremely low birth weight (ELBW) infants. Patients To date, we have performed TCPC on 134 ELBW infants weighing <2 kg at the time of the procedure, 54 of whom were <1 kg with the smallest weighing 640 g with a median gestation age of 25 weeks (range 23‐27 weeks). Interventions A comprehensive follow‐up strategy with the creation of the Memphis PDA Clinic was implemented. Outcome measures Respiratory support, tolerance of enteral feeds, growth, and neurodevelopmental progress are indicators of favorable outcomes. Results TCPC has benefited ELBW infants with faster weaning off the ventilator, increase in enteral feedings, and somatic growth with the overall shortening of the hospital length of stay. The Memphis PDA Clinic has ensured optimal postdischarge follow‐up to improve long‐term outcomes. Conclusions TCPC is a safe and effective alternative to manage ELBW infants with a hemodynamically significant PDA. Comprehensive follow‐up after discharge provided in a multispecialty clinic developed specifically for this unique population has been successful in improving outcomes.
Leah Apalodimas; Benjamin Rush Waller Iii; Ranjit Philip; Judy Crawford; Jorden Cunningham; Shyam Sathanandam. A comprehensive program for preterm infants with patent ductus arteriosus. Congenital Heart Disease 2019, 14, 90 -94.
AMA StyleLeah Apalodimas, Benjamin Rush Waller Iii, Ranjit Philip, Judy Crawford, Jorden Cunningham, Shyam Sathanandam. A comprehensive program for preterm infants with patent ductus arteriosus. Congenital Heart Disease. 2019; 14 (1):90-94.
Chicago/Turabian StyleLeah Apalodimas; Benjamin Rush Waller Iii; Ranjit Philip; Judy Crawford; Jorden Cunningham; Shyam Sathanandam. 2019. "A comprehensive program for preterm infants with patent ductus arteriosus." Congenital Heart Disease 14, no. 1: 90-94.
Background Patent ductus arteriosus (PDA) is highly prevalent in extremely low birth weight (ELBW), preterm infants. There are diverse management approaches for the PDA in ELBW infants. The objectives of this research were to identify current PDA management practices among cardiologists and neonatologists in the United States, describe any significant differences in management, and describe areas where practices align. Methods A survey of 10 questions based on the management of PDA in ELBW infants was conducted among 100 prominent neonatologists from 74 centers and 103 prominent cardiologists from 75 centers. Among the cardiologists, approximately 50% were interventionists who perform transcatheter PDA closures (TCPC). Fisher’s exact test was performed to compare practice variations among neonatologists and cardiologists. A potentially biased audience including a combination of health care providers belonging to cardiology, neonatology, and surgery were also surveyed during the International PDA Symposium. The results of this survey were not included for statistical comparison, due to this audience being potentially influenced by the Symposium. Results Statistically significant differences were identified between neonatologists and cardiologists regarding the impact of PDA closure on morbidity and mortality, with 80% cardiologists responding that it does vs 54% of neonatologists (P < 0.001), the need for PDA closure (P < .001), and the preferred method of PDA closure if indicated (P < .001). There was agreement between neonatologists and cardiologists on symptomatic therapy; however more neonatologists favored watchful waiting over intervention in contrast to more cardiologists favoring intervention over observation (77% vs 95%, P < .001). Survey responses also identified a need for further training and research on TCPC. Conclusion Neonatologists and cardiologists have notable differences in managing PDA, and continued discussion across cardiology and neonatology has the potential to facilitate more of a consensus on best management practices. Further investigation is needed to identify outcomes in transcatheter PDA closure, particularly in ELBW infants.
Shyam Sathanandam; Stephanie Whiting; Jorden Cunningham; David Zurakowski; Leah Apalodimas; B. Rush Waller; Ranjit Philip; Athar M. Qureshi. Practice variation in the management of patent ductus arteriosus in extremely low birth weight infants in the United States: Survey results among cardiologists and neonatologists. Congenital Heart Disease 2019, 14, 6 -14.
AMA StyleShyam Sathanandam, Stephanie Whiting, Jorden Cunningham, David Zurakowski, Leah Apalodimas, B. Rush Waller, Ranjit Philip, Athar M. Qureshi. Practice variation in the management of patent ductus arteriosus in extremely low birth weight infants in the United States: Survey results among cardiologists and neonatologists. Congenital Heart Disease. 2019; 14 (1):6-14.
Chicago/Turabian StyleShyam Sathanandam; Stephanie Whiting; Jorden Cunningham; David Zurakowski; Leah Apalodimas; B. Rush Waller; Ranjit Philip; Athar M. Qureshi. 2019. "Practice variation in the management of patent ductus arteriosus in extremely low birth weight infants in the United States: Survey results among cardiologists and neonatologists." Congenital Heart Disease 14, no. 1: 6-14.
Interventional pediatric cardiology is a specialty of pediatric cardiology that deals specifically with the catheter-based treatment of congenital heart diseases. Cardiac catheterization involves the evaluation and manipulation of the heart and surrounding vessels through catheters place in peripheral vessels. In this chapter we begin by discussing the significant difference between adult and pediatric interventional cardiology. We will discuss basic hemodynamic measurements performed in cardiac catheterization and its application to congenital heart disease. Stent and balloon catheters are briefly discussed. Finally, specific catheter based interventional techniques, indications, and complications for various pediatric congenital heart disease is described.
Neil Tailor; Ranjit Philip; Shyam Sathanandam. Cardiac Catheterization in Congenital Heart Disease. Congenital Heart Disease 2018, 1 .
AMA StyleNeil Tailor, Ranjit Philip, Shyam Sathanandam. Cardiac Catheterization in Congenital Heart Disease. Congenital Heart Disease. 2018; ():1.
Chicago/Turabian StyleNeil Tailor; Ranjit Philip; Shyam Sathanandam. 2018. "Cardiac Catheterization in Congenital Heart Disease." Congenital Heart Disease , no. : 1.
Background Patent ductus arteriosus (PDA) is common in extremely low birth weight (ELBW) infants. The objectives of this study were to describe our early clinical experience of transcatheter PDA closure (TCPC) in ELBW infants, compare outcomes with surgical ligation of PDA (SLP), and identify risk factors for prolonged respiratory support. Methods A retrospective review was performed comparing infants born 8 weeks of age were associated with prolonged (>30‐days) elevation of RSS ≥ 1 (OR = 5.4, 95%CI: 2.2–9.4, P < 0.01 and OR = 2.86, 95%CI: 1.5–4.2, P = 0.05 respectively). Overall complication rate for TCPC was 3.7%. Conclusions TCPC is feasible in infants as small as 640‐2000 g and can be performed safely in the majority. TCPC may offer faster weaning of respiratory support compared to SLP when performed earlier in life, and before the onset of elevated PAP.
Shyam Sathanandam; Kaitlin Balduf; Sandeep Chilakala; Kristen Washington; Kimberly Allen Rn; Christopher Knott-Craig; Benjamin Rush Waller; Ranjit Philip. Role of Transcatheter patent ductus arteriosus closure in extremely low birth weight infants. Catheterization and Cardiovascular Interventions 2018, 93, 89 -96.
AMA StyleShyam Sathanandam, Kaitlin Balduf, Sandeep Chilakala, Kristen Washington, Kimberly Allen Rn, Christopher Knott-Craig, Benjamin Rush Waller, Ranjit Philip. Role of Transcatheter patent ductus arteriosus closure in extremely low birth weight infants. Catheterization and Cardiovascular Interventions. 2018; 93 (1):89-96.
Chicago/Turabian StyleShyam Sathanandam; Kaitlin Balduf; Sandeep Chilakala; Kristen Washington; Kimberly Allen Rn; Christopher Knott-Craig; Benjamin Rush Waller; Ranjit Philip. 2018. "Role of Transcatheter patent ductus arteriosus closure in extremely low birth weight infants." Catheterization and Cardiovascular Interventions 93, no. 1: 89-96.
Govinda Paudel; Ranjit Philip; David Zurakowski; Kaitlin Balduf; Sarah Fahnhorst; Benjamin Waller; Shyam Sathanandam. ECHOCARDIOGRAPHIC GUIDANCE FOR TRANS-CATHETER DEVICE CLOSURE OF PATENT DUCTUS ARTERIOSUS IN EXTREMELY LOW BIRTH WEIGHT INFANTS. Journal of the American College of Cardiology 2018, 71, A576 .
AMA StyleGovinda Paudel, Ranjit Philip, David Zurakowski, Kaitlin Balduf, Sarah Fahnhorst, Benjamin Waller, Shyam Sathanandam. ECHOCARDIOGRAPHIC GUIDANCE FOR TRANS-CATHETER DEVICE CLOSURE OF PATENT DUCTUS ARTERIOSUS IN EXTREMELY LOW BIRTH WEIGHT INFANTS. Journal of the American College of Cardiology. 2018; 71 (11):A576.
Chicago/Turabian StyleGovinda Paudel; Ranjit Philip; David Zurakowski; Kaitlin Balduf; Sarah Fahnhorst; Benjamin Waller; Shyam Sathanandam. 2018. "ECHOCARDIOGRAPHIC GUIDANCE FOR TRANS-CATHETER DEVICE CLOSURE OF PATENT DUCTUS ARTERIOSUS IN EXTREMELY LOW BIRTH WEIGHT INFANTS." Journal of the American College of Cardiology 71, no. 11: A576.
Background The porcine small intestinal extracellular matrix reportedly has the potential to differentiate into viable myocardial cells. When used in tetralogy of Fallot repair, it may improve right ventricular function. We evaluated right ventricular function after repair of tetralogy of Fallot with extracellular matrix versus bovine pericardium. Method Subjects with non-transannular repair of tetralogy of Fallot with at least 1 year of follow-up were selected. The extracellular matrix and bovine pericardium groups were compared. We used three-dimensional right ventricular ejection fraction, right ventricle global longitudinal strain, and tricuspid annular plane systolic excursion to assess right ventricular function. Results The extracellular matrix group had 11 patients, whereas the bovine pericardium group had 10 patients. No differences between the groups were found regarding sex ratio, age at surgery, and cardiopulmonary bypass time. The follow-up period was 28±12.6 months in the extracellular matrix group and 50.05±17.6 months in the bovine pericardium group (p=0.001). The mean three-dimensional right ventricular ejection fraction (55.7±5.0% versus 55.3±5.2%, p=0.73), right ventricular global longitudinal strain (−18.5±3.0% versus −18.0±2.2%, p=0.44), and tricuspid annular plane systolic excursions (1.59±0.16 versus 1.59±0.2, p=0.93) were similar in the extracellular matrix group and in the bovine pericardium group, respectively. Right ventricular global longitudinal strain in healthy children is reported at −29±3% in literature. Conclusion In a small cohort of the patients undergoing non-transannular repair of tetralogy of Fallot, there was no significant difference in right ventricular function between groups having extracellular matrix versus bovine pericardium patches followed-up for more than 1 year. Lower right ventricular longitudinal strain noted in both the groups compared to healthy children.
Ronak Naik; Jason Johnson; Tk Susheel Kumar; Ranjit Philip; Umar Boston; Christopher J. Knott-Craig. Right ventricular function after repair of tetralogy of Fallot: a comparison between bovine pericardium and porcine small intestinal extracellular matrix. Cardiology in the Young 2017, 27, 1522 -1528.
AMA StyleRonak Naik, Jason Johnson, Tk Susheel Kumar, Ranjit Philip, Umar Boston, Christopher J. Knott-Craig. Right ventricular function after repair of tetralogy of Fallot: a comparison between bovine pericardium and porcine small intestinal extracellular matrix. Cardiology in the Young. 2017; 27 (8):1522-1528.
Chicago/Turabian StyleRonak Naik; Jason Johnson; Tk Susheel Kumar; Ranjit Philip; Umar Boston; Christopher J. Knott-Craig. 2017. "Right ventricular function after repair of tetralogy of Fallot: a comparison between bovine pericardium and porcine small intestinal extracellular matrix." Cardiology in the Young 27, no. 8: 1522-1528.
Experience with pericardial bioprostheses in young patients is limited. Accelerated degeneration of the Mitroflow valve has recently been reported. We report early accelerated structural valve degeneration with the Perimount Magna bioprosthesis, which has not been previously reported. Young patients with the Magna bioprosthesis are at high risk for rapid progression to severe stenosis, which underscores their need for more vigilant surveillance. The benefits and risks of these bioprosthetic valves must be weighed carefully when options for replacement in these young patients are discussed.
Ranjit Philip; Tk Susheel Kumar; B. Rush Waller; Mia McCoy; Christopher J. Knott-Craig. Near Catastrophic Accelerated Structural Degeneration of the Perimount Magna Pericardial Bioprosthesis in Children. The Annals of Thoracic Surgery 2016, 102, 308 -311.
AMA StyleRanjit Philip, Tk Susheel Kumar, B. Rush Waller, Mia McCoy, Christopher J. Knott-Craig. Near Catastrophic Accelerated Structural Degeneration of the Perimount Magna Pericardial Bioprosthesis in Children. The Annals of Thoracic Surgery. 2016; 102 (1):308-311.
Chicago/Turabian StyleRanjit Philip; Tk Susheel Kumar; B. Rush Waller; Mia McCoy; Christopher J. Knott-Craig. 2016. "Near Catastrophic Accelerated Structural Degeneration of the Perimount Magna Pericardial Bioprosthesis in Children." The Annals of Thoracic Surgery 102, no. 1: 308-311.
Objectives: The aim of this study was to describe and differentiate the morphology of patent ductus arteriosus (PDA) seen in children born prematurely from other PDA types. Background: PDAs are currently classified as types A‐E using the Krichenko's classification. Children born prematurely with a PDA morphology that did not fit this classification were described as Type F PDA. Methods: A review of 100 consecutive children who underwent transcatheter device closure of PDA was performed. The diameter and length (L) of the PDA and the device diameter (D) were indexed to the descending aorta (DA) diameter. Results: Comparison of 26 Type F PDAs was performed against, 29 Type A, 7 Type C and 32 Type E PDAs. Children with Type F PDAs (median 27.5 weeks gestation) were younger during the device occlusion compared with types A, C, and E (median age: 6 vs. 32, 11, and 42 months; P = 0.002). Type F PDAs were longer and larger, requiring a relatively large device for occlusion than types A, C, and E (Mean L/DA: 1.88 vs. 0.9, 1.21, and 0.89, P ≤ 0.01 and Mean D/DA: 1.04 vs. 0.46, 0.87, and 0.34, P ≤0.01). The Amplatzer vascular plug‐II (AVP‐II) was preferred for occlusion of Type F PDAs (85%; P <0.001). Conclusions: Children born prematurely have relatively larger and longer PDAs. These “fetal type PDAs” are best classified separately. We propose to classify them as Type F PDAs to add to types A‐E currently in use. The AVP‐II was effective in occluding Type F PDAs.
Ranjit Philip; B. Rush Waller; Vijaykumar Agrawal; Dena Wright; Alejandro Arevalo; David Zurakowski; Shyam Sathanandam. Morphologic characterization of the patent ductus arteriosus in the premature infant and the choice of transcatheter occlusion device. Catheterization and Cardiovascular Interventions 2015, 87, 310 -317.
AMA StyleRanjit Philip, B. Rush Waller, Vijaykumar Agrawal, Dena Wright, Alejandro Arevalo, David Zurakowski, Shyam Sathanandam. Morphologic characterization of the patent ductus arteriosus in the premature infant and the choice of transcatheter occlusion device. Catheterization and Cardiovascular Interventions. 2015; 87 (2):310-317.
Chicago/Turabian StyleRanjit Philip; B. Rush Waller; Vijaykumar Agrawal; Dena Wright; Alejandro Arevalo; David Zurakowski; Shyam Sathanandam. 2015. "Morphologic characterization of the patent ductus arteriosus in the premature infant and the choice of transcatheter occlusion device." Catheterization and Cardiovascular Interventions 87, no. 2: 310-317.
IntroductionHypoplastic left heart syndrome with an intact atrial septum is a poor predictor of outcomes. Prenatal assessment of pulmonary venous Doppler and emergent postnatal cardiac intervention may be associated with better outcomes.Materials and methodsA retrospective review of all hypoplastic left heart syndrome patients in two centres over a 5-year period was performed. Group 1 included patients with adequate inter-atrial communication. Group 2 included patients with prenatal diagnosis with an intact atrial septum who had immediate transcatheter intervention. Group 3 included patients with intact atrial septum who were not prenatally diagnosed and underwent either delayed intervention or no intervention before stage 1 palliation. Primary outcome was survival up to stage 2 palliation.ResultsThe incidence of hypoplastic left heart syndrome with a restrictive atrial communication was 11.2% (n=19 of 170). Overall survival to stage 2 or heart transplantation was 85% and 67% for Groups 1 and 2, respectively (n=129/151, n=8/12; p=0.03), and 0% (n=0/7) for Group 3. Survival benefits were observed between Groups 2 and 3 (pConclusionUsing a multidisciplinary approach and foetal pulmonary vein Doppler, time-saving measures can be instituted by delivering prenatally diagnosed neonates with hypoplastic left heart syndrome with intact atrial septum close to the cardiac catheterisation suite where left atrial decompression can be performed quickly and safely that may improve survival.
Shyam Sathanandam; Ranjit Philip; David Gamboa; Andrew Van Bergen; Michel N. Ilbawi; Christopher Knott-Craig; B. Rush Waller; Alexander J. Javois; Bettina F. Cuneo. Management of hypoplastic left heart syndrome with intact atrial septum: a two-centre experience. Cardiology in the Young 2015, 26, 1072 -1081.
AMA StyleShyam Sathanandam, Ranjit Philip, David Gamboa, Andrew Van Bergen, Michel N. Ilbawi, Christopher Knott-Craig, B. Rush Waller, Alexander J. Javois, Bettina F. Cuneo. Management of hypoplastic left heart syndrome with intact atrial septum: a two-centre experience. Cardiology in the Young. 2015; 26 (6):1072-1081.
Chicago/Turabian StyleShyam Sathanandam; Ranjit Philip; David Gamboa; Andrew Van Bergen; Michel N. Ilbawi; Christopher Knott-Craig; B. Rush Waller; Alexander J. Javois; Bettina F. Cuneo. 2015. "Management of hypoplastic left heart syndrome with intact atrial septum: a two-centre experience." Cardiology in the Young 26, no. 6: 1072-1081.
To establish reference scores for cardio-ankle vascular index (CAVI), a noninvasive measure of vascular function, which reflects the stiffness of arteries, in healthy children, to test for racial and ethnic differences, and to compare CAVI scores between overweight and normal weight children. Subjects included 292 children aged 10-18 years: 100 non-Hispanic whites, 89 non-Hispanic blacks, and 103 Hispanics. Subjects were grouped as normal weight (body mass index [BMI] 85th percentile for age). Blood pressure (BP) and CAVI scores were measured in all subjects. After controlling for age, sex, and BMI, normal weight black males had a higher CAVI score (indicating stiffer arteries) in comparison with Hispanic males and white males (5.53 ± 0.15 vs 5.13 ± 0.15 vs 5.02 ± 0.15, P = .04). BMI had an inverse association on the CAVI score (r = -0.335, P < .0001). In multivariable analysis, BMI and average CAVI scores were significant predictors of each other (R(2) = 0.37, P < .0001, R(2) = 0.21, P < .0001). There was no significant correlation between CAVI scores and resting BP values, confirming that CAVI scores were independent of concurrent BP values. Significant differences in vascular function exist among ethnic groups of children. Overweight children had lower CAVI scores, suggestive of vascular adaptation to obesity in early life. CAVI, by providing a noninvasive measure of vascular health, may help identify children at increased risk for cardiovascular disease.
Ranjit Philip; Bruce S. Alpert; Andreas Schwingshackl; Xin Huang; Douglas Blakely; Cynthia R. Rovnaghi; Quynh T. Tran; Andres' Velasquez; Alejandro Arevalo; Kanwaljeet Anand. Inverse Relationship between Cardio-Ankle Vascular Index and Body Mass Index in Healthy Children. The Journal of Pediatrics 2015, 167, 361 -365.e1.
AMA StyleRanjit Philip, Bruce S. Alpert, Andreas Schwingshackl, Xin Huang, Douglas Blakely, Cynthia R. Rovnaghi, Quynh T. Tran, Andres' Velasquez, Alejandro Arevalo, Kanwaljeet Anand. Inverse Relationship between Cardio-Ankle Vascular Index and Body Mass Index in Healthy Children. The Journal of Pediatrics. 2015; 167 (2):361-365.e1.
Chicago/Turabian StyleRanjit Philip; Bruce S. Alpert; Andreas Schwingshackl; Xin Huang; Douglas Blakely; Cynthia R. Rovnaghi; Quynh T. Tran; Andres' Velasquez; Alejandro Arevalo; Kanwaljeet Anand. 2015. "Inverse Relationship between Cardio-Ankle Vascular Index and Body Mass Index in Healthy Children." The Journal of Pediatrics 167, no. 2: 361-365.e1.
The Sano modification of the Norwood operation is a well-established first step palliation for hypoplastic left heart syndrome (HLHS). Theoretically, the first point of resistance to pulmonary flow should be in the proximal Sano, generating high Doppler flow velocity. Paradoxically, however, some patients have low gradients in the proximal Sano conduit. The objective of this study was to determine the hemodynamic and anatomic significance of low proximal Sano Doppler flow velocity and its clinical implications.
Shyam K. Sathanandam; Ranjit Philip; Andrew Van Bergen; David A. Roberson; Wei Cui; Michel N. Ilbawi; Alexander J. Javois; Tarek S. Husayni. Significance of Low Peak Doppler Velocity in the Proximal Sano Conduit in Hypoplastic Left Heart Syndrome. The Annals of Thoracic Surgery 2014, 98, 1378 -1385.
AMA StyleShyam K. Sathanandam, Ranjit Philip, Andrew Van Bergen, David A. Roberson, Wei Cui, Michel N. Ilbawi, Alexander J. Javois, Tarek S. Husayni. Significance of Low Peak Doppler Velocity in the Proximal Sano Conduit in Hypoplastic Left Heart Syndrome. The Annals of Thoracic Surgery. 2014; 98 (4):1378-1385.
Chicago/Turabian StyleShyam K. Sathanandam; Ranjit Philip; Andrew Van Bergen; David A. Roberson; Wei Cui; Michel N. Ilbawi; Alexander J. Javois; Tarek S. Husayni. 2014. "Significance of Low Peak Doppler Velocity in the Proximal Sano Conduit in Hypoplastic Left Heart Syndrome." The Annals of Thoracic Surgery 98, no. 4: 1378-1385.