To summarise key epidemiological and therapeutic research on osteoarthritis (OA) published between April 2024 and March 2025. A narrative review was conducted using the MEDLINE database, focusing on English-language studies involving human participants published between April 1, 2024 and March 31, 2025. Eligible studies included observational longitudinal studies, systematic reviews, meta-analyses, and phase II-IV randomised controlled trials (RCTs) examining OA treatment and epidemiology. A total of 1920 studies were screened by 3 authors, resulting in 133 studies considered for potential inclusion. Ultimately, 41 studies were selected. Inclusion was based on perceived importance and relevance to identifying risk factors or advancing OA treatment. The global burden of OA continues to rise, with a notable increase in early-onset OA, driven in part by obesity and joint injuries. Epidemiologically, body composition-characterised by high fat mass and low lean mass-emerged as a critical factor influencing OA severity and physical function. Furthermore, the presence of other chronic conditions significantly impacts OA progression and outcomes, and influences management choice, increasing the risk of patients receiving low-value care. Therapeutic interventions for OA, including intra-articular injections (e.g., corticosteroids, hyaluronic acid, stem cells) and pharmacological therapies (e.g., metformin, methotrexate), continue to show limited efficacy. Semaglutide, which targets obesity, demonstrated substantial weight and pain reductions in individuals with knee OA and obesity, suggesting a potential disease-modifying effect through weight loss. The past year's research highlights the complexity of OA and the limited effectiveness of current interventions. While therapies targeting obesity hold promise, further research is needed to confirm their role in disease modification. Personalised treatment approaches that integrate metabolic, biomechanical, and psychosocial factors may be crucial for advancing OA care management.

Urinary incontinence is a hygienic and psychosocial problem that often brings people to restrict their social life and to experience depression. The main aim of this study was to evaluate the impact of urinary incontinence on quality of life among residents of the Metropolitan City of Naples, Italy, using a newly designed multidimensional questionnaire. The secondary objective was to find which variables affect the quality of life and symptom severity in these patients. To do so, a sample composed of twenty-eight patients was recruited in a multicentre cross-sectional study. Most of the participants had a mild impairment (60%) concerning social life and self-perception, especially those whose education was above the primary level (p = 0.036) and those who followed a pelvic floor rehabilitation program (p = 0.002). Overflow urinary incontinence was associated with a greater deterioration in the aspirational and occupational domain (p = 0.044). Symptom severity was worse in those who had comorbidities (p = 0.038), who had a high body mass index (p = 0.008) or who used diuretics (p = 0.007). In conclusion, our results suggest that there is a significant impairment of quality of life in patients who have only primary education and who follow a pelvic floor rehabilitation program.

Myasthenia gravis is a rare neuromuscular disorder characterized by muscle weakness and fatigue. This review analyzes the most recent evidence regarding the effectiveness and safety of different rehabilitative approaches to the disease. The review was carried out in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A total of 365 articles were found in the main scientific databases. Applying the inclusion/exclusion criteria, 11 studies were admitted to the final phase of the review. Three different rehabilitative approaches were identified: physical training, respiratory training, and balance training. All rehabilitative modalities contributed to enhancing functional outcomes, reducing fatigue, and improving quality of life, but currently none can be recommended over another for the lack of cross-comparative studies. The included studies showed methodological quality from low to fair. Despite the range of rehabilitative interventions available, there is a lack of high-quality evidence. However, this review suggests that a multidisciplinary rehabilitation approach should be recommended to people with myasthenia gravis, and above all, for those with mild to moderate symptomatology.

Background: In education, lecturers play a crucial role in facilitating students’ learning process. However, only a few studies explored which lecturers’ characteristics can facilitate this process in higher education for rehabilitation healthcare professionals. Starting from students’ perspectives, our qualitative study investigated the lecturers’ characteristics that facilitate students’ learning process in the rehabilitation sciences. Methods: A qualitative interview study. We enrolled students attending the 2nd year of the Master of Science (MSc) degree in ‘Rehabilitation Sciences of Healthcare Professions’. Different themes were generated following a ‘Reflexive Thematic Analysis’. Results: Thirteen students completed the interviews. From their analysis, we generated five themes. Specifically, a lecturer that facilitates students’ learning process should be: 1) ‘A Performer who Interacts with the Classroom’, 2) A Flexible Planner who Adopts Innovative Teaching Skills’, 3) ‘A Motivator who Embraces Transformational Leadership’, 4) ‘A Facilitator Who Encourages a Constructive Learning Context’ and 5) ‘A Coach who Devises Strategies to Reach Shared Learning Goals’. Conclusions: The results of this study underscore the importance for lecturers in rehabilitation to cultivate a diverse set of skills drawn from the arts and performance, education, team building and leadership to facilitate students’ learning process. By developing these skills, lecturers can design lessons that are worth attending not only for their relevant content but also for their value in human experience.

Exercise is a first-line intervention for osteoarthritis (OA). However, exercise adherence remains low, and existing studies exploring factors influencing adherence have yielded inconclusive results based on quantitative data. This study aims to synthesise qualitative studies focused on the perceived facilitators and barriers affecting exercise adherence in individuals with OA. A thematic synthesis of qualitative studies was conducted. Relevant articles were sourced from MEDLINE, Cochrane Central Register of Controlled Trials, Embase, CINAHL, and PsychInfo until November 2024. Studies focused on adults (≥16 years) with hip or knee OA who had participated in exercise programmes to manage OA. The quality of the studies was assessed using the Critical Appraisal Skills Programme (CASP) tool. Data analysis followed Thematic Synthesis by Thomas & Harden to identify descriptive and analytical themes. The confidence of the evidence was evaluated through the Confidence in Evidence from Reviews of Qualitative Research (CERQual). A total of 21 studies involving 458 participants were included. From seven descriptive themes, three analytical themes were developed: (i) Mind-Body Connection, (ii) Social Support Systems, and (iii) Environmental Enablers. These themes underscore the importance of personal beliefs, experiences, and mindsets, alongside social and environmental factors, in promoting or hindering exercise adherence. This study highlights the multifaceted cognitive, social, and environmental factors influencing exercise adherence in individuals with OA. The findings suggest that a ‘one-size-fits-all’ approach is insufficient for promoting sustained exercise engagement. Future quantitative research should build upon these insights to develop tailored strategies for enhancing exercise adherence in people with OA.

From an active ageing perspective, investigating how adults use apps and wearables for health purposes might improve well-being strategies supported by widely adopted technologies. This study investigated adults' perceptions of using apps and wearables for health purposes. A qualitative interview study was conducted. Adults (+18) using an app/wearable to monitor at least one health variable (e.g. physical activity and diet) were eligible. Transcriptions were analysed using the Reflexive Thematic Analysis. Nineteen participants (34.3 ± 14.5 years; men/women: 8/11) joined the study and from their transcriptions 5 themes were created: 1) Easy and accurate monitoring of health: balancing users' needs and technological challenges; 2) Self-improvement and motivation: usefulness of rewarding behaviours and gamification towards achievements; 3) Requiring personalized apps and wearables: aesthetics and wearability; 4) Beyond simple monitoring: prevention and care throughout daily life; 5) Awareness of potentially dangerous digital data world: from distress to fixation. Apps and wearables were highly valued by our participants for effectively managing and enhancing their health and sports performance while ensuring education, motivation, ease of use, safety, and prevention. However, issues such as privacy concerns, wearability, and lack of integration need to be addressed to improve adoption, enhance usability and support active ageing initiatives.