Dr. Rachid Touzani

Novel heterocyclic compounds containing pyrazole, thiazole and pyridine moieties were designed and prepared based on the condensation reaction between 1,3-thiazole or aminopyridine derivatives and 1H-pyrazole,3,5-dimethyl-1H-pyrazole or 1,2,4-triazole. Their structures were confirmed with FTIR, ¹H and ¹³C NMR analyses. DPPH scavenging assay was used to evaluate their antioxidant potential. The ligand 4 showed the best antioxidant activity with an IC₅₀ = 4.67 μg/mL, while IC₅₀ values of the other compounds were found to be ranging from 20.56 to 45.32 μg/mL. DFT and molecular docking studies were performed in order to gain better insights and to understand the relationship between the structures of the studied compounds and their antioxidant activities. The results obtained revealed a good agreement between the experimental and the theoretical findings.

1 November 2019 in Journal of Molecular Structure

Journal Article

Performance and computational studies of two soluble pyran derivatives as corrosion inhibitors for mild steel in HCl

M. Khattabi

Fouad Benhiba

S. Tabti

A. Djedouani

A. El Assyry

A. Zarrouk

30 August 2002 in Molecules

Journal Article

2,3-Bifunctionalized Quinoxalines: Synthesis, DNA Interactions and Evaluation of Anticancer, Anti-tuberculosis and Antifungal Activity

Michael J. Waring

Taibi Ben Hadda

Ann T. Kotchevar

Abdelkrim Ramdani

Rachid Touzani

Tom Ellis

A variety of 2,3-bifunctionalized quinoxalines (6-14) have been prepared by the condensation of 1,6-disubstituted-hexan-1,3,4,6-tetraones (1-4) with o-phenylenediamine, (R,R)-1,2-diaminocyclohexane and p-nitro-o-phenylenediamine. It is concluded that strong intramolecular N-H----O bonds in the favoured keto-enamine form may be responsible for the minimal biological activities observed in DNA footprinting, antitubercular, anti-fungal and anticancer tests with these hyper π-conjugated quinoxaline derivatives. However, subtle alteration by addition of a nitro group affecting the charge distribution confers significant improvements in biological effects and binding to DNA.

1 February 2007 in Materials Letters

Journal Article

Ruthenium–ligand complex, an efficient inhibitor of steel corrosion in H3PO4 media

M. Benabdellah

Rachid Touzani

A. Dafali

Belkheir Hammouti

S. El Kadiri

About Me

Prof. Dr. Rachid Touzani is a Full Professor at the Department of Chemistry, Faculty of Sciences, University Mohammed Premier, Oujda, Morocco. He received, his B.A. in 1996 and his Ph.D. in Chemistry in 2001. He took a post-doc position at the Université de Rennes 1, France, (2001-2000), and the University of Ottawa, Canada (2002-2005). He then joined University Mohammed Premier as an Assistant Professor in 2005 and an Associate Professor in 2009, Then, he was a Full Professor from 2016 until now. In 2019, he was in the world's Top 2% of scientists. He has published more than 275 documents (Hindex = 34). His research interests include corrosion inhibitors, organic, organometallic, analytical, catalysis, green chemistry; Hirshfeld; ionic imprinted polymer; polyurethane; essential oils; and natural compounds synthetic methodology. He has supervised more than 50 PhD and Master students. He has participated in many conferences (8 book chapters, 5 books) and was a Fulbright visiting scholar in 2010.

Dr. Rachid Touzani

Dr. Rachid Touzani

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