Pradeep Kumar

Prof. Dr. Pradeep Kumar

Wits Advanced Drug Delivery Platform (WADDP) Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
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Research Focus & Metrics

Academic Career Length

18Years (2009-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2013 in Journal of Nanomaterials
Verified
Journal Article
Open access
PDF file
VPViness Pillay
Viness Pillay
CDClare Dott
Clare Dott
Yahya ChoonaraYahya Choonara
Yahya Choonara
CTCharu Tyagi
Charu Tyagi
LTLomas K Tomar
Lomas K Tomar
VNValence M K Ndesendo
Valence M K Ndesendo
Electrospinning is a fast emerging technique for producing ultrafine fibers by utilizing electrostatic repulsive forces. The technique has gathered much attention due to the emergence of nanotechnology that sparked worldwide research interest in nanomaterials for their preparation and application in biomedicine and drug delivery. Electrospinning is a simple, adaptable, cost‐effective, and versatile technique for producing nanofibers. For effective and efficient use of the technique,several processing parameters need to be optimized for fabricating polymeric nanofibers. The nanofiber morphology, size, porosity, surface area, and topography can be refined by varying these parameters. Such flexibility and diversity in nanofiber fabrication by electrospinning has broadened the horizons for widespread application of nanofibers in the areas of drug and gene delivery, wound dressing, and tissue engineering. Drug‐loaded electrospun nanofibers have been used in implants, transdermal systems, wound dressings, and as devices for aiding the prevention of postsurgical abdominal adhesions and infection. They show great promise for use in drug delivery provided that one can confidently control the processing variables during fabrication. This paper provides a concise incursion into the application of electrospun nanofibers in drug delivery and cites pertinent processing parameters that may influence the performance of the nanofibers when applied to drug delivery.

26 March 2010 in Journal of Heterocyclic Chemistry
Verified
Journal Article
Closed access
PDF file
VSVikas Sharma
Vikas Sharma
PKPradeep Kumar
Pradeep Kumar
DPDevender Pathak
Devender Pathak

1 February 2017 in Carbohydrate Polymers
Verified
Journal Article
Closed access
NMNonhlanhla Masina
Nonhlanhla Masina
Yahya ChoonaraYahya Choonara
Yahya Choonara
PKPradeep Kumar
Pradeep Kumar
LTLisa du Toit
Lisa du Toit
Mershen GovenderMershen Govender
Mershen Govender
VPViness Pillay
Viness Pillay

1 July 2014 in Journal of Controlled Release
Verified
Journal Article
Closed access
SISunaina Indermun
Sunaina Indermun
RLRegina Luttge
Regina Luttge
Yahya ChoonaraYahya Choonara
Yahya Choonara
PKPradeep Kumar
Pradeep Kumar
LTLisa du Toit
Lisa du Toit
VPViness Pillay
Viness Pillay

29 April 2022 in Antibiotics
Verified
Journal Article
Open access
PDF file
PNPalanichamy Nandhini
Palanichamy Nandhini
PKPradeep Kumar
Pradeep Kumar
SMSuresh Mickymaray
Suresh Mickymaray
AAAbdulaziz Alothaim
Abdulaziz Alothaim
Jayaprakash somasundaramJayaprakash somasundaram
Jayaprakash somasundaram
MRMariappan Rajan
Mariappan Rajan
Staphylococcus aureus (S. aureus) is a Gram-positive bacterium that may cause life-threatening diseases and some minor infections in living organisms. However, it shows notorious effects when it becomes resistant to antibiotics. Strain variants of bacteria, viruses, fungi, and parasites that have become resistant to existing multiple antimicrobials are termed as superbugs. Methicillin is a semisynthetic antibiotic drug that was used to inhibit staphylococci pathogens. The S. aureus resistant to methicillin is known as methicillin-resistant Staphylococcus aureus (MRSA), which became a superbug due to its defiant activity against the antibiotics and medications most commonly used to treat major and minor infections. Successful MRSA infection management involves rapid identification of the infected site, culture and susceptibility tests, evidence-based treatment, and appropriate preventive protocols. This review describes the clinical management of MRSA pathogenesis, recent developments in rapid diagnosis, and antimicrobial treatment choices for MRSA.

1 November 2014 in Biotechnology Advances
Verified
Journal Article
Closed access
BCBibi F. Choonara
Bibi F. Choonara
Yahya ChoonaraYahya Choonara
Yahya Choonara
PKPradeep Kumar
Pradeep Kumar
DBDivya Bijukumar
Divya Bijukumar
LTLisa du Toit
Lisa du Toit
VPViness Pillay
Viness Pillay