Noncompliance with therapy is one possible explanation for the observation that long-term graft survival is not sufficiently improved by the development in immunosuppression. The aim of the study was to explore the prevalence, characteristics and risk factors of noncompliance with immunosuppression. A total of 161 adult kidney transplant recipients were interviewed about their self-rated health, social support, education, stress from adverse effects and compliance with the immunosuppression. The prevalence of subclinical noncompliance was 54%. Noncompliant patients declared significantly worse self-rated health, less satisfaction with social support and higher stress from adverse effects. Male gender (OR 7.5, CI 2.4-23.39), high stress from adverse effects (OR 12.27, CI 2.44-61.88), fair self-rated health (OR 4.45, CI 1.04-19.55) and fair satisfaction with social support (OR 4.55, CI 1.08-19.24) were predictors of noncompliance. Standardized detection methods should be developed with the aim of identifying patients who are at risk of noncompliance in order to prevent graft loss.

Objective:The purpose of this study was to test the structure and endorsement of drinking motives and their links to alcohol use among 11- to 19-year-olds from 13 European countries.Method:Confirma...

Participation in organized leisure-time activities (OLTA) has been linked to healthy youth development. This study aimed to assess whether participation in OLTA is associated with both physical and mental health in adolescents, and whether this association differs by pattern of activity participation, age and gender. The present study was based on data from the 2013/2014 Health Behaviour in School-aged Children study in the Czech Republic. This data concerned 10,503 adolescents (49.2 % boys) aged 11, 13 and 15. A cluster analysis was carried out to obtain patterns of activity participation and yielded five groups (all-rounders, artists, individual sports, team sports and inactive). The association between participation in types of OLTA and physical and mental health was analysed using logistic regression models adjusted for age and gender. We also assessed interactions between types of OLTA and gender and age. Participation in OLTA was associated with better self-rated health and higher life satisfaction regardless of gender or age. Participation in team or individual sports was associated with better general health and less frequent health complaints in boys, while participation in art activities was associated with lower occurrence of health complaints in girls and 11-year-olds. Participation in OLTA is associated with better physical and mental health in adolescents. The association varies by pattern of activity participation and is partly gender- and age-specific.