The study of land use transition has generally become an important breakthrough point to deeply understand the human-land interaction and reveal major socio-economic development issues and related environmental effects. Attempting to provide scientific support for sustainable land use and environmental management, this review systematically analyzes the overall picture, development trends, key fields and hot topics of land use transition research in the past two decades from a comprehensive perspective, which incorporates two complementary parts including the systematic quantitative literature review (based on CiteSpace) and the traditional literature review. The results reveal that: a. current research presents three characteristics, i.e., focusing on complex social issues, driven by realistic demand, and research branches becoming clearer and more systematic; b. there are four key fields and hot topics in land use transition research, i.e., i. theories and hypothesis of land use transition; ii. measuring land use transition; iii. the impacts of land use transition on “social-economic-ecological” system; iv. drivers and regulation of land use transition. However, challenges remain, current land use transition research is still to some extent fragmented, and it should be enriched by integrating with land system science. The dominant morphology biased should be redressed by underlining the recessive morphology transition process. Meanwhile, new techniques and methods are necessary to observe, track, monitor and model the recessive attributes. Finally, distant drivers of land use transition should not be ignored in this rapidly globalizing world.