Chiara Ambrosi

Chiara Ambrosi

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Chiara Ambrosi


Research Focus & Metrics

Academic Career Length

1Year (2026-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 May 2026 in Livers
Verified
Journal Article
Open access
PDF file
VBVittoria Benintende
Vittoria Benintende
LBLuca Bettazzoni
Luca Bettazzoni
NRNicola Reggidori
Nicola Reggidori
CAChiara Ambrosi
Chiara Ambrosi
MPMonica Patrignani
Monica Patrignani
LILuca Ielasi
Luca Ielasi
Sarcoidosis is a multisystemic inflammatory disease defined by non-caseating granuloma formation in involved organs. The liver is the third most implicated organ after the lungs and lymph nodes. Due to its frequently asymptomatic presentation, the true prevalence of hepatic sarcoidosis may be understated. Increased levels of alkaline phosphatase and gamma-glutamyl transferase are the most frequent biochemical abnormalities. The liver biopsy is still the gold standard and reveals non-caseating granulomas in almost all cases. The use of corticosteroids and ursodeoxycholic acid results in a significant decrease in biochemical parameters. However, the clinical course of hepatic sarcoidosis is diverse and requires individualized management strategies, especially to prevent hepatic complications. This review aims to synthesize the current evidence on epidemiology, pathogenesis, diagnostic approaches, and therapeutic strategies for this disease.