Perpetua SEP Modjadji

Prof. Dr. Perpetua SEP Modjadji

Non-communicable diseases Research Unit, South African Medical Research Council, Cape Town, Western Cape, South Africa
orcid
Specialist Scientist at SAMRC

Research Focus & Metrics

Academic Career Length

12Years (2015-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
16 February 2016 in PLOS ONE
Verified
Journal Article
Open access
PDF file
EMEric Maimela
Eric Maimela
MAMarianne Alberts
Marianne Alberts
Perpetua SEP ModjadjiPerpetua SEP Modjadji
Perpetua SEP Modjadji
SCSolomon Ramphai Choma
Solomon Ramphai Choma
SDSekgothe A. Dikotope
Sekgothe A. Dikotope
Jean-Pierre Van GeertruydenJean-Pierre Van Geertruyden
Jean-Pierre Van Geertruyden
The aim of the study was to determine the prevalence and determinants of chronic non-communicable disease (NCD) risk factors in a rural community in the Limpopo Province of South Africa. This survey was conducted using the WHO "STEPwise approach to the surveillance of non-communicable diseases" (STEPS) methodology. Participants were residents of the Dikgale HDSS site and standardised international protocols were used to measure behavioural risk factors (smoking, alcohol consumption, fruit and vegetable intake and, physical activity) and physical characteristics (weight, height, waist and hip circumferences and blood pressure–BP). Fasting blood glucose, triglyceride, cholesterol and HDL-C were determined in 732 participants. Data were analysed using STATA 12 for Windows. The prevalence of current smokers amongst the participants was 13.7%, of which 81.3% were daily smokers. Alcohol was consumed by 16.3% of the participants. The majority of participants (88.6%) had low daily intake of fruit and vegetables and low physical activity (66.5%). The prevalence of hypertension amongst the participants was 38.2%. Overweight, obesity and high waist circumference were prevalent in females. The cardio-metabolic risk profile was not significantly different between men and women. People who were older than 40 years, overweight or obese and those who consumed alcohol were more likely to be hypertensive. Smoking was associated significantly with older age, males, never married and divorced people. Alcohol consumption was associated with older age, males, low educational status and low income. High levels of risk factors for NCDs among adults in the Dikgale HDSS suggest an urgent need for health interventions to control these risk factors at the population level in order to reduce the prevalence of NCDs.

1 July 2021 in The Lancet Global Health
Verified
Journal Article
Open access
Perpetua SEP ModjadjiPerpetua SEP Modjadji
Perpetua SEP Modjadji

9 August 2019 in BMC Public Health
Verified
Journal Article
Open access
PDF file
Perpetua SEP ModjadjiPerpetua SEP Modjadji
Perpetua SEP Modjadji
Sphiwe MadibaSphiwe Madiba
Sphiwe Madiba
In South Africa, the occurrence of the double burden of malnutrition is on the rise at a household level predisposing children and their mothers to negative health outcomes. However, few studies have been conducted at a household level. Therefore, we studied a double burden of malnutrition using child-mother pairs in a rural setting. A cross-sectional quantitative survey was conducted among 508 child-mother pairs selected from primary schools using a multistage sampling in a rural Dikgale Health and Demographic Site in Limpopo Province, South Africa. Anthropometric measurements of children and mothers, and socio-demographic data were collected. WHO AnthroPlus was used to generate body-mass-index z-scores of children and the BMI was used to indicate overweight and obesity among the mothers. Mann Whitney test was used to compare the means of variables between sexes and age groups, while the prevalence of thinness and overweight/obesity were compared using a chi-square. Multivariate logistic regression with a stepwise backward elimination procedure, controlling for confounding, was used to determine the association between the thinness and overweight/obesity and the covariates. Twenty five percent (25%) of the children were thin, 4% were overweight and 1% obese, while mothers were overweight (27.4%) and 42.3% obesity (42.3%) were observed among the mothers. The odds of being thin were higher in boys than in girls (AOR = 1.53, 95%CI: 1.01–2.35). Overweight/obese mothers were more likely to have thin children (AOR = 1.48, 95% CI: 1.01–2.18) and less likely to have overweight/obese children (AOR = 0.18, 95%CI: 0.07–0.46). A double burden of malnutrition was observed on a household level with thinness among children and overweight/obesity among mothers. A need to address the dual problems of undernutrition and rapidly rising trends of overweight/obesity cannot be over-emphasized.

9 October 2020 in Children
Verified
Journal Article
Open access
PDF file
Perpetua SEP ModjadjiPerpetua SEP Modjadji
Perpetua SEP Modjadji
Dineo MolokwaneDineo Molokwane
Dineo Molokwane
PUPatricia Ukegbu
Patricia Ukegbu
Preschool children consume diets inadequate to meet their macro and micronutrient requirements, which ultimately affect their nutritional status due to lack of dietary diversity. A cross sectional study was conducted to investigate the association between dietary diversity scores (DDS) and the nutritional status of 379 preschool children in North West Province of South Africa. A 24 h qualitative recall by mothers of their children’s food consumption was used to calculate DDS based on 12-foods groups following Food and Agriculture Organization protocols. DDS was calculated by counting each of 12-food groups and classified as low (≤4), medium (5–8) and high (9–12). The weight and height of children were measured and height-for-age (HAZ), weight-for-age (WAZ) and BMI-for-age (BAZ) z-scores were calculated based on 2006 WHO standards. Stunting, underweight and thinness were defined as HAZ, WAZ and BAZ < −2SD, respectively. Linear and logistic regression analyses were used to assess the association between DDS and the nutritional indicators. Mean age for children was 4 ± 0.7 years, and the prevalence of stunting (29%), underweight (13%) and thinness (6%) was observed. Mean DDS was 4.39 ± 1.55 out of 12-food groups, with a prevalence of 61% and 39% for low and medium DDS, respectively. Cereals (100%) accounted for the main food group consumed, while fish and other seafood (17%) were the least consumed. Consumption of a diversified diet was associated with lower odds of being stunted [AOR = 0.25, 95%CI: 0.10 to 0.92] among the four-year olds, while in the unadjusted model, 5-year-olds had lower odds of being underweight [OR = −0.32, 95%CI: −0.57 to 0.07]. The findings of this study reinforce the importance of continued nutrition education of mothers, caregivers and preschool staff on the need to ensure consumption of diverse food sources in order to improve the nutritional status of children. Further studies are recommended on the association of DDS with the nutritional status, and factors associated with low dietary diversity among preschool children.

8 April 2015 in BMC Health Services Research
Verified
Journal Article
Open access
PDF file
EMEric Maimela
Eric Maimela
Jean-Pierre Van GeertruydenJean-Pierre Van Geertruyden
Jean-Pierre Van Geertruyden
MAMarianne Alberts
Marianne Alberts
Perpetua SEP ModjadjiPerpetua SEP Modjadji
Perpetua SEP Modjadji
HMHerman Meulemans
Herman Meulemans
HBHilde Bastiaens
Hilde Bastiaens
Preventive health care represents the future for health care delivery in South Africa to improve management of chronic diseases as this has been implemented for some time in several countries to tackle the increasing burden of chronic diseases. Individual person’s health is unique, as they move in and out of chronic and acute health care phases, there is need to integrate chronic and acute care constructs to improve continuity of care and maximize health and improve wellbeing. The aim of this study was to determine the perceptions and perspectives of chronic patients’ and nurses regarding chronic disease management in terms of barriers, facilitators and their experiences. To meet our aim we used qualitative methods involving the collection of information by means of focus group discussions in Dikgale Health and Demographic Surveillance System (HDSS). All data was recorded, transcribed verbatim and analysed using data-driven thematic analysis. Our study showed that chronic disease patients have a first contact with health care professionals at the primary health care level in the study area. The main barriers mentioned by both the health care workers and chronic disease patients are lack of knowledge on chronic diseases, shortage of medication and shortage of nurses in the clinics which causes patients to wait for a long periods in a clinic. Health care workers are poorly trained on the management of chronic diseases. Lack of supervision by the district and provincial health managers together with poor dissemination of guidelines has been found to be a contributing factor to lack of knowledge in nurses among the clinics within the study area. Both patients and nurses mentioned the need to involve community health workers and traditional healers and integrate their services in order to early detect and manage chronic diseases in the community. Nurses and chronic disease patients mentioned similar barriers to chronic disease management. Concerted action is needed to strengthen the delivery of medications at the clinics, improve the chronic disease knowledge for both nurses and patients by conducting in-service trainings or workshops, increase the involvement of community health workers and establish a link (through formal referral system) with traditional healers.

13 August 2015 in International Journal of Epidemiology
Verified
Journal Article
Open access
PDF file
MAMarianne Alberts
Marianne Alberts
SDSekgothe A Dikotope
Sekgothe A Dikotope
SCSolomon Ramphai Choma
Solomon Ramphai Choma
MMMatshane L Masemola
Matshane L Masemola
Perpetua SEP ModjadjiPerpetua SEP Modjadji
Perpetua SEP Modjadji
PBPeter Byass
Peter Byass
As Alberts and colleagues explained in 1999, 1 during the 1990s concerns arose in the newly democratic South Africa that exposures to various non-communicable disease (NCD) risk factors were increasing rapidly as lifestyles changed. The Dikgale Health and Demographic Surveillance System (DHDSS) was conceived along the same lines as the nearby Agincourt HDSS, 2 but on a much smaller scale. It was primarily intended as a sampling framework for monitoring NCDs and their risk factors on a population basis. The DHDSS was one of the founder members of the INDEPTH Network. 3