Prof. Dr. Raffaele Serra
Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Calabria, Italy
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Academic Career Length
20Years (2007-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications8 March 2015 in Expert Review of Anti-infective Therapy
Journal Article
Raffaele SerraRGRaffaele Grande
Raffaele GrandeLBLucia Butrico
Lucia Butrico
ARAlessio Rossi
Alessio Rossi
USUgo Francesco Settimio
Ugo Francesco Settimio
SFStefano de Franciscis
Stefano de Franciscis +3
Chronic leg ulcers affect 1-2% of the general population and are related to increased morbidity and health costs. Staphylococcus aureus and Pseudomonas aeruginosa are the most common bacteria isolated from chronic wounds. They can express virulence factors and surface proteins affecting wound healing. The co-infection of S. aureus and P. aeruginosa is more virulent than single infection. In particular, S. aureus and P. aeruginosa have both intrinsic and acquired antibiotic resistance, making clinical management of infection a real challenge, particularly in patients with comorbidity. Therefore, a correct and prompt diagnosis of chronic wound infection requires a detailed knowledge of skin bacterial flora. This is a necessary prerequisite for tailored pharmacological treatment, improving symptoms, and reducing side effects and antibiotic resistance.
1 September 2016 in International Journal of Surgery
Journal Article
MCMarco Cannistrà
Marco CannistràMRMichele Ruggiero
Michele RuggieroAZAlessandra Zullo
Alessandra ZulloGGGiuseppe Gallelli
Giuseppe GallelliSSSimone Serafini
Simone SerafiniBNBruno Nardo
Bruno Nardo +4
Hepatic ischemia reperfusion injury (IRI) is not only a pathophysiological process involving the liver, but also a complex systemic process affecting multiple tissues and organs. Hepatic IRI can seriously impair liver function, even producing irreversible damage, which causes a cascade of multiple organ dysfunction. Many factors, including anaerobic metabolism, mitochondrial damage, oxidative stress and secretion of ROS, intracellular Ca(2+) overload, cytokines and chemokines produced by KCs and neutrophils, and NO, are involved in the regulation of hepatic IRI processes. Matrix Metalloproteinases (MMPs) can be an important mediator of early leukocyte recruitment and target in acute and chronic liver injury associated to ischemia. MMPs and neutrophil gelatinase-associated lipocalin (NGAL) could be used as markers of I-R injury severity stages. This review explores the relationship between factors and inflammatory pathways that characterize hepatic IRI, MMPs and current pharmacological approaches to this disease.
26 March 2013 in Wound Repair and Regeneration
Journal Article
Raffaele SerraGBGianluca Buffone
Gianluca BuffoneDFDaniela Falcone
Daniela Falcone
VMVincenzo Molinari
Vincenzo Molinari
MSMonica Scaramuzzino
Monica Scaramuzzino
SFStefano de Franciscis
Stefano de Franciscis +1
1 August 2016 in Annals of Vascular Surgery
Journal Article
Raffaele SerraLBLucia Butrico
Lucia Butrico
FFFrancesco Fugetto
Francesco FugettoMCMariia Dmitrievna Chibireva
Mariia Dmitrievna Chibireva
AMAlberto Malva
Alberto Malva
SFStefano de Franciscis
Stefano de Franciscis
+4
25 December 2019 in International Wound Journal
Journal Article
GGGiuseppe Gallelli
Giuseppe Gallelli
ECErika Cione
Erika Cione
Raffaele SerraALAntonio Leo
Antonio Leo
RCRita Citraro
Rita Citraro
Luca Gallelli +5
11 October 2013 in Journal of Basic and Clinical Physiology and Pharmacology
Journal Article
ASAntonio Siniscalchi
Antonio Siniscalchi
Luca GallelliGMGiovanni Malferrari
Giovanni Malferrari
DPDomenico Pirritano
Domenico Pirritano
Raffaele SerraGSGiovambattista De Sarro
Giovambattista De Sarro +1
Stroke represents the most frequent cause of permanent disability in adults worldwide. Cerebral ischemia triggers the pathological pathways of the ischemic cascade and causes irreversible neuronal injury in the ischemic core within minutes of the onset. Elements of the immune system are involved in all stages of ischemic cascade from acute intravascular events triggered by the interruption of blood supply, to the parenchymal processes leading to brain damage and to the ensuing tissue repair. In this review, we will provide a brief overview of current understanding of the role of cytokines and brain inflammation during acute ischemic stroke.
About Me
Raffaele Serra is currently Full Professor of Vascular Surgery at the University Magna Graecia of Catanzaro. He received his Doctor of Medicine Degree from the University Magna Graecia of Catanzaro, Catanzaro, Italy, in 1999, and a Ph.D. in Clinical and Experimental Biotechnology in Veins and Lymphatic Diseases from the Faculty of Medicine, Department of Surgical Science, University of Perugia, Perugia, Italy, in 2009. From 2008 to 2016, he was an assistant professor of surgery at the University Magna Graecia of Catanzaro, Catanzaro, Italy. From 2016 to 2025, he has been an Associate Professor of Vascular Surgery at the University Magna Graecia of Catanzaro, Catanzaro, Italy. In 2017, he achieved the national scientific qualification as a Full Professor of Surgery, and in 2020, he achieved the national scientific qualification as a Full Professor of Vascular Surgery. His research interests mainly focus on general surgery, vascular surgery, phlebology, lymphology, and biomarkers. He has 260 scientific international papers with an h index factor of 35 and more than 4300 citations to his work (Scopus, 14 December 2023).