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Dr. Ondrej Kalita
Neurosurgery, Palacký University, Olomouc, Olomoucký Kraj, Czech Republic
'%3e%3cpath%20d='M22.1642%2019.0924C21.7317%2018.068%2021.1041%2017.1375%2020.3163%2016.3527C19.5309%2015.5656%2018.6006%2014.9381%2017.5766%2014.5048C17.5674%2014.5002%2017.5582%2014.4979%2017.5491%2014.4933C18.9774%2013.4616%2019.9059%2011.7811%2019.9059%209.88504C19.9059%206.74408%2017.3611%204.19922%2014.2201%204.19922C11.0792%204.19922%208.53429%206.74408%208.53429%209.88504C8.53429%2011.7811%209.46282%2013.4616%2010.8912%2014.4956C10.882%2014.5002%2010.8728%2014.5025%2010.8636%2014.5071C9.83652%2014.9404%208.91487%2015.5617%208.1239%2016.355C7.33685%2017.1404%206.70933%2018.0707%206.276%2019.0947C5.85031%2020.0972%205.62072%2021.172%205.59967%2022.2609C5.59905%2022.2853%205.60335%2022.3097%205.61229%2022.3325C5.62123%2022.3553%205.63465%2022.376%205.65174%2022.3935C5.66883%2022.4111%205.68926%2022.425%205.71182%2022.4345C5.73437%2022.444%205.7586%2022.4489%205.78308%2022.4489H7.15868C7.25956%2022.4489%207.3398%2022.3686%207.3421%2022.2701C7.38795%2020.5001%208.09868%2018.8425%209.35506%2017.5861C10.655%2016.2862%2012.3814%2015.5709%2014.2201%2015.5709C16.0588%2015.5709%2017.7852%2016.2862%2019.0852%2017.5861C20.3415%2018.8425%2021.0523%2020.5001%2021.0981%2022.2701C21.1004%2022.3709%2021.1807%2022.4489%2021.2815%2022.4489H22.6571C22.6816%2022.4489%2022.7058%2022.444%2022.7284%2022.4345C22.751%2022.425%2022.7714%2022.4111%2022.7885%2022.3935C22.8056%2022.376%2022.819%2022.3553%2022.8279%2022.3325C22.8369%2022.3097%2022.8412%2022.2853%2022.8406%2022.2609C22.8176%2021.165%2022.5907%2020.0989%2022.1642%2019.0924ZM14.2201%2013.8284C13.1678%2013.8284%2012.1773%2013.418%2011.4322%2012.6729C10.6871%2011.9278%2010.2767%2010.9374%2010.2767%209.88504C10.2767%208.83271%2010.6871%207.84227%2011.4322%207.09715C12.1773%206.35204%2013.1678%205.94165%2014.2201%205.94165C15.2724%205.94165%2016.2629%206.35204%2017.008%207.09715C17.7531%207.84227%2018.1635%208.83271%2018.1635%209.88504C18.1635%2010.9374%2017.7531%2011.9278%2017.008%2012.6729C16.2629%2013.418%2015.2724%2013.8284%2014.2201%2013.8284Z'%20fill='%238590A2'/%3e%3c/g%3e%3c/svg%3e)
Co-authors
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Research Focus & Metrics
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Academic Career Length
23Years (2004-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications15 August 2008 in Cell Cycle
Journal Article
PKPetra Knizetova
Petra Knizetova
JEJiri Ehrmann
Jiri Ehrmann
AHAlice Hlobilkova
Alice Hlobilkova
IVIveta Vancova
Iveta Vancova
OKOndrej Kalita
Ondrej KalitaJBJiri Bartek
Jiri Bartek
+1
Vascular endothelial growth factor (VEGF) plays a crucial role in angiogenesis and progression of malignant brain tumors. Given the significance of tumor microenvironment in general, and the establ...
11 January 2013 in Journal of Neuro-Oncology
Journal Article
VBVladimir Balik
Vladimir BalikJSJosef Srovnal
Josef Srovnal
ISIgor Sulla
Igor Sulla
OKOndrej Kalita
Ondrej KalitaTFTatiana Foltanova
Tatiana Foltanova
MHMarian Hajduch
Marian Hajduch +2
1 January 2009 in Neoplasma
Journal Article
AHA. Hlobilkova
A. HlobilkovaJEJ. Ehrmann
J. Ehrmann
PKP. Knizetova
P. Knizetova
VKV. Krejci
V. Krejci
OKOndrej Kalita
Ondrej KalitaZKZ. Kolar
Z. KolarAnalysis of VEGF, Flt-1, Flk-1, nestin and MMP-9 in relation to astrocytoma pathogenesis and progression.
3 December 2021 in Applied Immunohistochemistry & Molecular Morphology
Journal Article
ZŠZuzana Šporiková
Zuzana ŠporikováRSRastislav Slavkovsky
Rastislav SlavkovskyLTLucie Tuckova
Lucie TuckovaOKOndrej Kalita
Ondrej KalitaMHMagdalena Megova Houdova
Magdalena Megova HoudovaMVMiroslav Vaverka
Miroslav Vaverka +3
Patients below 55 years were genetically studied because the prevalence of isocitrate dehydrogenase 1 (IDH1) decreases in older patients and on grounds of cost-effectiveness, as suggested by the World Health Organization (WHO) in 2016. The aim of our study was to use novel massively parallel sequencing (MPS) approaches to examine rare variants of IDH1/2 in Czech diffuse astrocytic and oligodendroglial tumors (gliomas) patients below 55 years of age who had been immunohistochemically (IHC) diagnosed as IDH1 R132H negative. The IHC IDH1 status (wild type or mutant) of 275 tissue samples was analyzed using antibodies against the IDH1 R132H protein. Sixty-three samples of 55 years old patients with IHC IDH1 WT status were genotyped using two different MPS technologies to detect rare IDH1 and IDH2 variants. The tiered IHC (60 positive) and molecular (10 positive) approach thus revealed that 70 of the 275 samples (25%) bore IDH1/IDH2 mutations. The combined molecular and IHC approach thus revealed that 70 of the 275 samples (25%) considered in the study bore IDH1/IDH2 mutations. IHC detection of the IDH1 R132H variant should be routinely complemented with MPS to detect rare IDH1/2 variants in glioma patients below 55 years of age with negative IHC result of IDH R132H variant.
26 May 2011 in International Journal of Surgical Oncology
Journal Article
OKOndrej Kalita
Ondrej KalitaIntramedullary spinal cord metastasis (ISCM) is the rarest type of CNS involvement by systemic malignant tumours. Optimal management of patients with ISCMs remains ambiguous. Based on two cases reported from our department, we focused on the strategy for intramedullary spinal cord metastases surgery.
3 December 2008 in Journal of Neuro-Oncology
Journal Article
LHLumír Hrabálek
Lumír HrabálekOKOndrej Kalita
Ondrej KalitaHSHana Svebisova
Hana SvebisovaJEJiri Ehrmann
Jiri Ehrmann
MHMarian Hajduch
Marian HajduchMKMiroslav Kala
Miroslav Kala
+1
About Me
Work Experience
9/1997-5/2006—Neurosurgical residency—Dpt of Neurosurgery, University Hospital and Faculty of Medicine and Dentistry of Palacky University.
5/2006–present—Fully boarded neurosurgeon—Dpt of Neurosurgery, University Hospital and Faculty of Medicine and Dentistry of Palacky University.
1/2010–present—Lecturer/teacher/tutor at the Faculty of Medicine and Dentistry of Palacky University in Olomouc.
17/2017–present—Appointed as assistant professor (doc.) at Palacky University in Olomouc.
Personal Skills
• Fully graduated neurosurgeon–onco-neurosurgical specialist.
• Ward head of Dpt of Neurosurgery—leadership (team of four physicians and ten nurses).
• Lecturer and tutor of students at the Faculty of Medicine and Dentistry of Palacky University in Olomouc.
• Reviewer of grant agencies and medical journals.
Main topic of interest: brain tumors.
Memberships
• Czech neurosurgical society JEP.
• Czech neurologocal society JEP.
• Czech society for oncology society JEP (The Neuro-Oncologic Section).
• European Association of Neuro-Oncology (EANO).
• European Association of Neurosurgical Societies (EANS).
• The Society for Neuro-Oncology (SNO).
• Congress of Neurological Surgeons (CNS).
• Central-Europe Neurosurgical Society (CENS).