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Dr. filomena lelario
Dipartimento di Scienze, Università degli Studi della Basilicata, Potenza, Italy

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0 Analytical Chemistry
0 Environmental Chemistry
0 Gas Chromatography
0 GC-MS
0 LC-MS

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Liquid chromatography
LC-MS
Photocatalysis
Gas Chromatography
GC-MS
photodegradation
LC-MS/MS

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Journal article
Published: 10 August 2021 in Catalysts
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Crude oil can undergo biotic and abiotic transformation processes in the environment. This article deals with the fate of an Italian crude oil under simulated solar irradiation to understand (i) the modification induced on its composition by artificial ageing and (ii) the transformations arising from different advanced oxidation processes (AOPs) applied as oil-polluted water remediation methods. The AOPs adopted were photocatalysis, sonolysis and, simultaneously, photocatalysis and sonolysis (sonophotocatalysis). Crude oil and its water-soluble fractions underwent analysis using GC-MS, liquid-state 1H-NMR, Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS), and fluorescence. The crude oil after light irradiation showed (i) significant modifications induced by the artificial ageing on its composition and (ii) the formation of potentially toxic substances. The treatment produced oil oxidation with a particular effect of double bonds oxygenation. Non-polar compounds present in the water-soluble oil fraction showed a strong presence of branched alkanes and a good amount of linear and aromatic alkanes. All remediation methods utilised generated an increase of C5 class and a decrease of C6–C9 types of compounds. The analysis of polar molecules elucidated that oxygenated compounds underwent a slight reduction after photocatalysis and a sharp decline after sonophotocatalytic degradation. Significant modifications did not occur by sonolysis.

ACS Style

Filomena Lelario; Giuliana Bianco; Sabino Bufo; Laura Scrano. Simulated Ageing of Crude Oil and Advanced Oxidation Processes for Water Remediation since Crude Oil Pollution. Catalysts 2021, 11, 954 .

AMA Style

Filomena Lelario, Giuliana Bianco, Sabino Bufo, Laura Scrano. Simulated Ageing of Crude Oil and Advanced Oxidation Processes for Water Remediation since Crude Oil Pollution. Catalysts. 2021; 11 (8):954.

Chicago/Turabian Style

Filomena Lelario; Giuliana Bianco; Sabino Bufo; Laura Scrano. 2021. "Simulated Ageing of Crude Oil and Advanced Oxidation Processes for Water Remediation since Crude Oil Pollution." Catalysts 11, no. 8: 954.

Review
Published: 05 July 2021 in Molecules
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Diterpenoid alkaloids are natural compounds having complex structural features with many stereo-centres originating from the amination of natural tetracyclic diterpenes and produced primarily from plants in the Aconitum, Delphinium, Consolida genera. Corals, Xenia, Okinawan/Clavularia, Alcyonacea (soft corals) and marine sponges are rich sources of diterpenoids, despite the difficulty to access them and the lack of availability. Researchers have long been concerned with the potential beneficial or harmful effects of diterpenoid alkaloids due to their structural complexity, which accounts for their use as pharmaceuticals as well as their lousy reputation as toxic substances. Compounds belonging to this unique and fascinating family of natural products exhibit a broad spectrum of biological activities. Some of these compounds are on the list of clinical drugs, while others act as incredibly potent neurotoxins. Despite numerous attempts to prepare synthetic products, this review only introduces the natural diterpenoid alkaloids, describing ‘compounds’ structures and classifications and their toxicity and bioactivity. The purpose of the review is to highlight some existing relationships between the presence of substituents in the structure of such molecules and their recognised bioactivity.

ACS Style

Amin Thawabteh; Alà Thawabteh; Filomena Lelario; Sabino Bufo; Laura Scrano. Classification, Toxicity and Bioactivity of Natural Diterpenoid Alkaloids. Molecules 2021, 26, 4103 .

AMA Style

Amin Thawabteh, Alà Thawabteh, Filomena Lelario, Sabino Bufo, Laura Scrano. Classification, Toxicity and Bioactivity of Natural Diterpenoid Alkaloids. Molecules. 2021; 26 (13):4103.

Chicago/Turabian Style

Amin Thawabteh; Alà Thawabteh; Filomena Lelario; Sabino Bufo; Laura Scrano. 2021. "Classification, Toxicity and Bioactivity of Natural Diterpenoid Alkaloids." Molecules 26, no. 13: 4103.

Review
Published: 25 June 2021 in Separations
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Apples represent a greater proportion of the worldwide fruit supply, due to their availability on the market and to the high number of existing cultivar varieties and apple-based products (fresh fruit, fruit juice, cider and crushed apples). Several studies on apple fruit metabolites are available, with most of them focusing on their healthy properties’ evaluation. In general, the metabolic profile of apple fruits strongly correlates with most of their peculiar characteristics, such as taste, flavor and color. At the same time, many bioactive molecules could be identified as markers of a specific apple variety. Therefore, a complete description of the analytical protocols commonly used for apple metabolites’ characterization and quantification could be useful for researchers involved in the identification of new phytochemical compounds from different apple varieties. This review describes the analytical methods published in the last ten years, in order to analyze the most important primary and secondary metabolites of Malus domestica fruits. In detail, this review gives an account of the spectrophotometric, chromatographic and mass spectrometric methods. A discussion on the quantitative and qualitative analytical shortcomings for the identification of sugars, fatty acids, polyphenols, organic acids, carotenoids and terpenes found in apple fruits is reported.

ACS Style

Maria Acquavia; Raffaella Pascale; Luca Foti; Giuseppe Carlucci; Laura Scrano; Giuseppe Martelli; Monica Brienza; Donatella Coviello; Giuliana Bianco; Filomena Lelario. Analytical Methods for Extraction and Identification of Primary and Secondary Metabolites of Apple (Malus domestica) Fruits: A Review. Separations 2021, 8, 91 .

AMA Style

Maria Acquavia, Raffaella Pascale, Luca Foti, Giuseppe Carlucci, Laura Scrano, Giuseppe Martelli, Monica Brienza, Donatella Coviello, Giuliana Bianco, Filomena Lelario. Analytical Methods for Extraction and Identification of Primary and Secondary Metabolites of Apple (Malus domestica) Fruits: A Review. Separations. 2021; 8 (7):91.

Chicago/Turabian Style

Maria Acquavia; Raffaella Pascale; Luca Foti; Giuseppe Carlucci; Laura Scrano; Giuseppe Martelli; Monica Brienza; Donatella Coviello; Giuliana Bianco; Filomena Lelario. 2021. "Analytical Methods for Extraction and Identification of Primary and Secondary Metabolites of Apple (Malus domestica) Fruits: A Review." Separations 8, no. 7: 91.

Journal article
Published: 18 May 2020 in Catalysts
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Commercial non-steroidal anti-inflammatory drugs (NSAIDs) are considered as toxic to the environment since they induce side effects when consumed by humans or aquatic life. Ibuprofen is a member of the NSAID family and is widely used as an anti-inflammatory and painkiller agent. Photolysis is a potentially important method of degradation for several emerging contaminants, and individual compounds can undergo photolysis to various degrees, depending on their chemical structure. The efficiency oftitanium dioxide (TiO2) and photocatalysis was investigated for the removal of ibuprofen from the aquatic environment, and the performance of these different processes was evaluated. In heterogeneous photocatalysis, two experiments were carried out using TiO2 as (i) dispersed powder, and (ii) TiO2 immobilized on the active surface of commercial coated glass. The kinetics of each photoreaction was determined, and the identification of the photoproducts was carried out by liquid chromatography coupled with Fourier-transform ion cyclotron resonance mass spectrometry (LC-FTICR MS). The overall results suggest that the TiO2 active thin layer immobilized on the glass substrate can avoid recovery problems related to the use of TiO2 powder in heterogeneous photocatalysis and may be a promising tool toward protecting the environment from emerging contaminants such as ibuprofen and its derivatives.

ACS Style

Samer Khalaf; Jawad H. Shoqeir; Filomena Lelario; Sabino A. Bufo; Rafik Karaman; Laura Scrano. TiO2 and Active Coated Glass Photodegradation of Ibuprofen. Catalysts 2020, 10, 560 .

AMA Style

Samer Khalaf, Jawad H. Shoqeir, Filomena Lelario, Sabino A. Bufo, Rafik Karaman, Laura Scrano. TiO2 and Active Coated Glass Photodegradation of Ibuprofen. Catalysts. 2020; 10 (5):560.

Chicago/Turabian Style

Samer Khalaf; Jawad H. Shoqeir; Filomena Lelario; Sabino A. Bufo; Rafik Karaman; Laura Scrano. 2020. "TiO2 and Active Coated Glass Photodegradation of Ibuprofen." Catalysts 10, no. 5: 560.

Journal article
Published: 19 April 2019 in Toxins
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Eggplant contains glycoalkaloids (GAs), a class of nitrogen-containing secondary metabolites of great structural variety that may have both adverse and beneficial biological effects. In this study, we performed a complete survey of GAs and their malonylated form, in two genotypes of eggplants: A commercial cultivated type, Mirabella (Mir), with purple peel and bitter taste and a local landrace, named Melanzana Bianca di Senise (Sen), characterized by white peel with purple strip and a typical sweet aroma. Besides the analysis of their morphological traits, nineteen glycoalkaloids were tentatively identified in eggplant berry extracts based upon LC-ESI-FTICR-MS analysis using retention times, elution orders, high-resolution mass spectra, as well as high-resolution fragmentation by IRMPD. The relative signal intensities (i.e., ion counts) of the GAs identified in Mir and Sen pulp extracts showed as solamargine, and its isomers are the most abundant. In addition, anticholinesterase and antioxidant activities of the extracts were evaluated. Pulp tissue was found to be more active in inhibiting acetylcholinesterase enzyme than peel showing an inhibitory effect higher than 20% for Mir pulp. The identification of new malonylated GAs in eggplant is proposed.

ACS Style

Filomena Lelario; Susanna De Maria; Anna Rita Rivelli; Daniela Russo; Luigi Milella; Sabino Aurelio Bufo; Laura Scrano. A Complete Survey of Glycoalkaloids Using LC-FTICR-MS and IRMPD in a Commercial Variety and a Local Landrace of Eggplant (Solanum melongena L.) and their Anticholinesterase and Antioxidant Activities. Toxins 2019, 11, 230 .

AMA Style

Filomena Lelario, Susanna De Maria, Anna Rita Rivelli, Daniela Russo, Luigi Milella, Sabino Aurelio Bufo, Laura Scrano. A Complete Survey of Glycoalkaloids Using LC-FTICR-MS and IRMPD in a Commercial Variety and a Local Landrace of Eggplant (Solanum melongena L.) and their Anticholinesterase and Antioxidant Activities. Toxins. 2019; 11 (4):230.

Chicago/Turabian Style

Filomena Lelario; Susanna De Maria; Anna Rita Rivelli; Daniela Russo; Luigi Milella; Sabino Aurelio Bufo; Laura Scrano. 2019. "A Complete Survey of Glycoalkaloids Using LC-FTICR-MS and IRMPD in a Commercial Variety and a Local Landrace of Eggplant (Solanum melongena L.) and their Anticholinesterase and Antioxidant Activities." Toxins 11, no. 4: 230.

Journal article
Published: 01 December 2018 in Toxins
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Solanaceae plants produce glycoalkaloids (GAs) that affect various physiological processes of herbivorous insects and they are being tested as potential alternatives for synthetic pesticides. They cause lethal and sublethal effects. Nevertheless, their mode of action remains unclear. Therefore, we examined the effects of Solanum nigrum fruit extracts and pure glycoalkaloids on a model beetle, Tenebrio molitor. Plant extracts or pure alkaloids were added to the food of the larvae for three days. The lipid, glycogen, and protein content in the fat body and the midgut were determined, and the contractility of the heart, hindgut, and oviduct muscles was tested using the video-microscopy technique. Finally, the ultrastructure of the fat body and the midgut was observed using electron microscopy. No lethal effects were noted. Sublethal changes were observed in the content of biomolecules, malformations of organelles, chromatin condensation, and heart and oviduct contractility. The observed effects differed between the tested glycoalkaloids and the extract. Both the extract and pure GAs have a wide range of effects that may result in impaired development, food intake, and reproduction. Some early effects may be used as bioindicators of stress. The effects of the extract and pure alkaloids suggest that the substances produced by the plant may act additively or synergistically.

ACS Style

Marta Spochacz; Szymon Chowański; Monika Szymczak; Filomena Lelario; Sabino A. Bufo; Zbigniew Adamski. Sublethal Effects of Solanum nigrum Fruit Extract and Its Pure Glycoalkaloids on the Physiology of Tenebrio molitor (Mealworm). Toxins 2018, 10, 504 .

AMA Style

Marta Spochacz, Szymon Chowański, Monika Szymczak, Filomena Lelario, Sabino A. Bufo, Zbigniew Adamski. Sublethal Effects of Solanum nigrum Fruit Extract and Its Pure Glycoalkaloids on the Physiology of Tenebrio molitor (Mealworm). Toxins. 2018; 10 (12):504.

Chicago/Turabian Style

Marta Spochacz; Szymon Chowański; Monika Szymczak; Filomena Lelario; Sabino A. Bufo; Zbigniew Adamski. 2018. "Sublethal Effects of Solanum nigrum Fruit Extract and Its Pure Glycoalkaloids on the Physiology of Tenebrio molitor (Mealworm)." Toxins 10, no. 12: 504.

Research article
Published: 01 October 2018 in Chemical Biology & Drug Design
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A respected number of drugs suffer from bitter taste which results in patient incompliance. With the aim of solving the bitterness of guaifenesin, dimethyl maleate, maleate, glutarate, succinate and dimethyl succinate prodrugs were designed and synthesized. Molecular orbital methods were utilized for the design of the ester prodrugs. The density functional theory (DFT) calculations revealed that the hydrolysis efficiency of the synthesized prodrugs is significantly sensitive to the pattern of substitution on C=C bond and distance between the nucleophile and the electrophile. The hydrolysis of the prodrugs was largely affected by the pH of the medium. The experimental t1/2for the hydrolysis of guaifenesin dimaleate ester prodrugs in 1N HCl was the least and for guaifenesin dimethyl succinate was the highest. Functional heterologous expression of TAS2R14, a broadly tuned bitter taste receptor responding to guaifenesin, and experiments using these prodrugs revealed that, while some of the prodrugs still activated the receptor similarly or even stronger than the parent substance, succinate derivatization resulted in the complete loss of receptor responses. The predicted binding modes of guaifenesin and its prodrugs to the TAS2R14 homology model suggest that the decreased activity of the succinate derivatives may be caused by a clash with Phe247. This article is protected by copyright. All rights reserved.

ACS Style

Amin Thawabtah; Filomena Lelario; Laura Scrano; Sabino A. Bufo; Stefanie Nowak; Maik Behrens; Antonella Di Pizio; Masha Y. Niv; Rafik Karaman. Bitterless guaifenesin prodrugs-design, synthesis, characterization, in vitro kinetics, and bitterness studies. Chemical Biology & Drug Design 2018, 93, 262 -271.

AMA Style

Amin Thawabtah, Filomena Lelario, Laura Scrano, Sabino A. Bufo, Stefanie Nowak, Maik Behrens, Antonella Di Pizio, Masha Y. Niv, Rafik Karaman. Bitterless guaifenesin prodrugs-design, synthesis, characterization, in vitro kinetics, and bitterness studies. Chemical Biology & Drug Design. 2018; 93 (3):262-271.

Chicago/Turabian Style

Amin Thawabtah; Filomena Lelario; Laura Scrano; Sabino A. Bufo; Stefanie Nowak; Maik Behrens; Antonella Di Pizio; Masha Y. Niv; Rafik Karaman. 2018. "Bitterless guaifenesin prodrugs-design, synthesis, characterization, in vitro kinetics, and bitterness studies." Chemical Biology & Drug Design 93, no. 3: 262-271.

Journal article
Published: 14 July 2018 in Ecotoxicology and Environmental Safety
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Plant-derived substances, because of high biological activity, arouse interest of many scientists. Thus, plant extracts and pure substances are intensively studied on various insects as potential insecticides. In such studies, D. melanogaster is one of the most important model organisms. In our studies, we analysed the contents of two plant extracts and tested the activity of their main components against fruit flies and compared observed effects to effects caused by crude extracts. Then, we assessed the development of the next, unexposed generation. The chemical analysis of extracts revealed the presence of numerous glycoalkaloids and glucosinolates in Solanum nigrum and Armoracia rusticana extracts. These extracts, as well as their main components, revealed lethal and sublethal effects, such as the altered developmental time of various life stages and malformations of imagoes. Interestingly, the results for the extracts and pure main compounds often varied. Some of the results were also observed in the unexposed generation. These results confirm that the tested plants produce a range of substances with potential insecticidal effects. The different effects of extracts and pure main components suggest the presence of minor compounds, which should be tested as insecticides.

ACS Style

Szymon Chowański; Ewa Chudzińska; Filomena Lelario; Emanuela Ventrella; Paweł Marciniak; Mariola Miądowicz-Kobielska; Marta Spochacz; Monika Szymczak; Laura Scrano; Sabino Aurelio Bufo; Zbigniew Adamski. Insecticidal properties of Solanum nigrum and Armoracia rusticana extracts on reproduction and development of Drosophila melanogaster. Ecotoxicology and Environmental Safety 2018, 162, 454 -463.

AMA Style

Szymon Chowański, Ewa Chudzińska, Filomena Lelario, Emanuela Ventrella, Paweł Marciniak, Mariola Miądowicz-Kobielska, Marta Spochacz, Monika Szymczak, Laura Scrano, Sabino Aurelio Bufo, Zbigniew Adamski. Insecticidal properties of Solanum nigrum and Armoracia rusticana extracts on reproduction and development of Drosophila melanogaster. Ecotoxicology and Environmental Safety. 2018; 162 ():454-463.

Chicago/Turabian Style

Szymon Chowański; Ewa Chudzińska; Filomena Lelario; Emanuela Ventrella; Paweł Marciniak; Mariola Miądowicz-Kobielska; Marta Spochacz; Monika Szymczak; Laura Scrano; Sabino Aurelio Bufo; Zbigniew Adamski. 2018. "Insecticidal properties of Solanum nigrum and Armoracia rusticana extracts on reproduction and development of Drosophila melanogaster." Ecotoxicology and Environmental Safety 162, no. : 454-463.

Book chapter
Published: 25 April 2017 in Reference Series in Phytochemistry
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There is an ever-increasing interest in the biological effects of glucosinolates (GSLs), due to their anticarcinogenic properties and potential to contribute to dietary phytonutrient consumption, thereby improving human health and well-being. Cruciferous vegetables are unique in that they are rich sources of GSLs. Several epidemiological studies have shown that a high intake of cruciferous vegetables, for example, cabbage, broccoli, or Brussels sprouts, has beneficial influence on human health. A new window of investigations has been opened by mass spectrometry (MS) and its combination with the various chromatographic techniques has proved to be highly successful to gain reliable data about the presence and abundance of GSLs in vegetables. The purpose of this chapter is focused on the methods that are currently available for their qualitative and quantitative analysis by MS and tandem MS (MS/MS). Emphasis is placed on the description and value of existing methods as well as on the many MS applications reported for GSL analysis.

ACS Style

Giuliana Bianco; Raffaella Pascale; Filomena Lelario; Sabino A. Bufo; Tommaso R. I. Cataldi. Investigation of Glucosinolates by Mass Spectrometry. Reference Series in Phytochemistry 2017, 431 -461.

AMA Style

Giuliana Bianco, Raffaella Pascale, Filomena Lelario, Sabino A. Bufo, Tommaso R. I. Cataldi. Investigation of Glucosinolates by Mass Spectrometry. Reference Series in Phytochemistry. 2017; ():431-461.

Chicago/Turabian Style

Giuliana Bianco; Raffaella Pascale; Filomena Lelario; Sabino A. Bufo; Tommaso R. I. Cataldi. 2017. "Investigation of Glucosinolates by Mass Spectrometry." Reference Series in Phytochemistry , no. : 431-461.

Journal article
Published: 01 March 2017 in Applied Clay Science
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ACS Style

Filomena Lelario; Ido Gardi; Yael Mishael; Noam Dolev; Tomas Undabeytia; Shlomo Nir; Laura Scrano; Sabino A. Bufo. Pairing micropollutants and clay-composite sorbents for efficient water treatment: Filtration and modeling at a pilot scale. Applied Clay Science 2017, 137, 225 -232.

AMA Style

Filomena Lelario, Ido Gardi, Yael Mishael, Noam Dolev, Tomas Undabeytia, Shlomo Nir, Laura Scrano, Sabino A. Bufo. Pairing micropollutants and clay-composite sorbents for efficient water treatment: Filtration and modeling at a pilot scale. Applied Clay Science. 2017; 137 ():225-232.

Chicago/Turabian Style

Filomena Lelario; Ido Gardi; Yael Mishael; Noam Dolev; Tomas Undabeytia; Shlomo Nir; Laura Scrano; Sabino A. Bufo. 2017. "Pairing micropollutants and clay-composite sorbents for efficient water treatment: Filtration and modeling at a pilot scale." Applied Clay Science 137, no. : 225-232.

Article
Published: 29 September 2016 in Rapid Communications in Mass Spectrometry
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Glycoalkaloids play a key role in the plant protection system against phytopathogens including fungi, viruses, bacteria, insects and worms. They can be toxic to humans if consumed in high concentrations causing gastrointestinal disturbances. The structural characterization of the major spirosolane glycoalkaloids, solasonine, solamargine, α-tomatine and dehydrotomatine, were investigated by positive electrospray ionization (ESI) coupled with a hybrid linear ion trap (LIT) and Fourier transform ion cyclotron resonance (FTICR) mass spectrometer. Tandem mass spectrometric analysis of spirosolane glycoalkaloids was performed by both collision-induced dissociation (CID) within the LIT and infrared multiphoton dissociation (IRMPD) in conjunction with the FTICR cell. Several common product ions were observed, generated by losses of the sugar moiety or aglycone fragmentation in the B- or E-ring, that can provide information on the accurate mass of aglycone and the primary sequence and branching of the oligosaccharide chains. Thanks to the multistage CID it was possible to understand the fragmentation pathways and thanks to the high resolution of IRMPD-FTICR the elemental compositions of product ions were obtained. Because the investigated tandem mass spectra data were acquired with high mass accuracy, unambiguous interpretation and determination of the chemical compositions for the majority of detected fragment ions were feasible. From these data, generalized fragmentation pathways were proposed, providing guidance for the characterization of unknown glycoalkaloids in plants. Copyright © John Wiley & Sons, Ltd.

ACS Style

F. Lelario; Cristiana Labella; G. Napolitano; L. Scrano; Sabino A. Bufo. Fragmentation study of major spirosolane-type glycoalkaloids by collision-induced dissociation linear ion trap and infrared multiphoton dissociation Fourier transform ion cyclotron resonance mass spectrometry. Rapid Communications in Mass Spectrometry 2016, 30, 2395 -2406.

AMA Style

F. Lelario, Cristiana Labella, G. Napolitano, L. Scrano, Sabino A. Bufo. Fragmentation study of major spirosolane-type glycoalkaloids by collision-induced dissociation linear ion trap and infrared multiphoton dissociation Fourier transform ion cyclotron resonance mass spectrometry. Rapid Communications in Mass Spectrometry. 2016; 30 (22):2395-2406.

Chicago/Turabian Style

F. Lelario; Cristiana Labella; G. Napolitano; L. Scrano; Sabino A. Bufo. 2016. "Fragmentation study of major spirosolane-type glycoalkaloids by collision-induced dissociation linear ion trap and infrared multiphoton dissociation Fourier transform ion cyclotron resonance mass spectrometry." Rapid Communications in Mass Spectrometry 30, no. 22: 2395-2406.

Book chapter
Published: 26 August 2016 in Reference Series in Phytochemistry
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There is an ever-increasing interest in the biological effects of glucosinolates (GSLs), due to their anticarcinogenic properties and potential to contribute to dietary phytonutrient consumption, thereby improving human health and well-being. Cruciferous vegetables are unique in that they are rich sources of GSLs. Several epidemiological studies have shown that a high intake of cruciferous vegetables, for example, cabbage, broccoli, or Brussels sprouts, has beneficial influence on human health. A new window of investigations has been opened by mass spectrometry (MS) and its combination with the various chromatographic techniques has proved to be highly successful to gain reliable data about the presence and abundance of GSLs in vegetables. The purpose of this chapter is focused on the methods that are currently available for their qualitative and quantitative analysis by MS and tandem MS (MS/MS). Emphasis is placed on the description and value of existing methods as well as on the many MS applications reported for GSL analysis.

ACS Style

Giuliana Bianco; Raffaella Pascale; Filomena Lelario; Sabino A. Bufo; Tommaso R. I. Cataldi. The Investigation of Glucosinolates by Mass Spectrometry. Reference Series in Phytochemistry 2016, 1 -32.

AMA Style

Giuliana Bianco, Raffaella Pascale, Filomena Lelario, Sabino A. Bufo, Tommaso R. I. Cataldi. The Investigation of Glucosinolates by Mass Spectrometry. Reference Series in Phytochemistry. 2016; ():1-32.

Chicago/Turabian Style

Giuliana Bianco; Raffaella Pascale; Filomena Lelario; Sabino A. Bufo; Tommaso R. I. Cataldi. 2016. "The Investigation of Glucosinolates by Mass Spectrometry." Reference Series in Phytochemistry , no. : 1-32.

Journal article
Published: 24 July 2016 in Plant, Soil and Environment
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ACS Style

Rivelli Ar; Filomena Lelario; R. Agneta; C. Möllers; S. De Maria. Variation of glucosinolates concentration and root growth of horseradish as affected by nitrogen and sulphur supply. Plant, Soil and Environment 2016, 62, 307 -313.

AMA Style

Rivelli Ar, Filomena Lelario, R. Agneta, C. Möllers, S. De Maria. Variation of glucosinolates concentration and root growth of horseradish as affected by nitrogen and sulphur supply. Plant, Soil and Environment. 2016; 62 (No. 7):307-313.

Chicago/Turabian Style

Rivelli Ar; Filomena Lelario; R. Agneta; C. Möllers; S. De Maria. 2016. "Variation of glucosinolates concentration and root growth of horseradish as affected by nitrogen and sulphur supply." Plant, Soil and Environment 62, no. No. 7: 307-313.

Journal article
Published: 21 July 2016 in Microscopy Research and Technique
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Beet Armyworm, Spodoptera exigua is a herbivorous moth and a serious pest of many economically important plants, which are used as food sources. Because of rigorous standards of food quality, usage of synthetic insecticides in crop protection, against pests, is limited. Solanaceae plant extracts may be a relatively cheap source of efficient natural insecticides that can limit usage of synthetic substances. Their biological activity is not fully known. In particular, ultrastructural studies, using transmission electron microscopy, are not usual. In the present article we describe the effects of sublethal concentrations of tomato and potato leaf extracts against S. exigua. Acute lethal effects were not observed. Both extracts exerted similar effects within midgut and fat body cells. Midgut cells were not significantly altered while fat body cells showed prominent swelling of nuclear envelope and endoplasmic reticulum, vacuolization of mitochondria and fusion of fat droplets. These changes were much more intensive within groups exposed to potato than tomato extracts at highest concentration at least. Light microscopy was used to observe and document developmental alterations of S. exigua exposed to potato and tomato leaf extracts. Potato leaf extracts significantly decreased hatching success and caused morphological malformations of imagoes. Among them, malformations of wings were the most prominent. Interestingly, these effects were not observed within populations exposed to tomato extracts at highest concentration at least.

ACS Style

Zbigniew Adamski; Katarzyna Radtke; Agnieszka Kopiczko; Szymon Chowański; Paweł Marciniak; Monika Szymczak; Marta Spochacz; Patrizia Falabella; Filomena Lelario; Laura Scrano; Sabino A. Bufo. Ultrastructural and developmental toxicity of potato and tomato leaf extracts to beet armyworm,Spodoptera exigua(lepidoptera: noctuidae). Microscopy Research and Technique 2016, 79, 948 -958.

AMA Style

Zbigniew Adamski, Katarzyna Radtke, Agnieszka Kopiczko, Szymon Chowański, Paweł Marciniak, Monika Szymczak, Marta Spochacz, Patrizia Falabella, Filomena Lelario, Laura Scrano, Sabino A. Bufo. Ultrastructural and developmental toxicity of potato and tomato leaf extracts to beet armyworm,Spodoptera exigua(lepidoptera: noctuidae). Microscopy Research and Technique. 2016; 79 (10):948-958.

Chicago/Turabian Style

Zbigniew Adamski; Katarzyna Radtke; Agnieszka Kopiczko; Szymon Chowański; Paweł Marciniak; Monika Szymczak; Marta Spochacz; Patrizia Falabella; Filomena Lelario; Laura Scrano; Sabino A. Bufo. 2016. "Ultrastructural and developmental toxicity of potato and tomato leaf extracts to beet armyworm,Spodoptera exigua(lepidoptera: noctuidae)." Microscopy Research and Technique 79, no. 10: 948-958.

Journal article
Published: 01 May 2016 in Journal of Photochemistry and Photobiology A: Chemistry
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This study aims to present the effectiveness of different advanced oxidation processes (AOPs) as photolysis (UV mercury arc and Xe-arc), ozone, ozone/Hg-UV, and photocatalysis (suspended and immobilized TiO2) for the degradation of the fungicide mepanipyrim in aqueous solutions. A well-known commercial product Pilkington Active™ Blue glass has been tested as immobilized TiO2 system. Experiments were performed in batch mode at laboratory scale and results were compared in terms of disappearance kinetics. Transformation products (TPs) were identified by Surveyor LC system coupled to a hybrid LTQ-FTICR (7-Tesla) mass spectrometer (MS). Simple mechanisms of degradation for different AOPs were proposed. New by-products formed during the degradation processes were identified. Since primarily hydroxy derivatives were identified in aqueous suspensions, the mechanism of degradation was probably based on hydroxyl radical attack. The greatest difference in the quality of transformation products was observed between the heterogeneous photocatalysis using suspended TiO2 and Pilkington Active™ Blue glass system. The inhibition percentage of bioluminescence from Vibro fischeri — as a toxicity parameter—increased during the irradiation time due to the residual concentration of the parent compound and transformation products generated.\ud Discover the world's researc

ACS Style

F. Lelario; M. Brienza; S.A. Bufo; L. Scrano. Effectiveness of different advanced oxidation processes (AOPs) on the abatement of the model compound mepanipyrim in water. Journal of Photochemistry and Photobiology A: Chemistry 2016, 321, 187 -201.

AMA Style

F. Lelario, M. Brienza, S.A. Bufo, L. Scrano. Effectiveness of different advanced oxidation processes (AOPs) on the abatement of the model compound mepanipyrim in water. Journal of Photochemistry and Photobiology A: Chemistry. 2016; 321 ():187-201.

Chicago/Turabian Style

F. Lelario; M. Brienza; S.A. Bufo; L. Scrano. 2016. "Effectiveness of different advanced oxidation processes (AOPs) on the abatement of the model compound mepanipyrim in water." Journal of Photochemistry and Photobiology A: Chemistry 321, no. : 187-201.

Journal article
Published: 14 March 2016 in Acta Physiologiae Plantarum
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Horseradish (Armoracia rusticana) is a rich source of glucosinolates (GLS), a class of secondary metabolites, nitrogen and sulfur compounds found in Brassicaceae family. Variations of content and composition of nine GLS in horseradish plants grown with N alone and N plus S were evaluated in the above- and below-ground portions at different developmental stages. Total GLS concentration was significantly higher in the above-ground tissues compared to the roots (97.8 vs 11.6 µmol g−1 dw); it responded positively to N and S supply in roots (11.5 in N alone and 15.8 µmol g−1 dw in N plus S treatments with respect to 7.4 µmol g−1 dw of the untreated control) without significant variations in the above-ground tissues. In both portions, total GLS concentration showed the greatest values at the beginning of plant regrowth and then decreased throughout the plant development till the end of the growing period. Among classes, the aliphatic GLS were the most abundant accounting for over 73 and 97 % of the total GLS in roots and above-ground tissues, respectively. Whereas, aromatic and indole GLS were present at roughly equivalent levels in both portions. GLS classes varied differently depending on developmental stage and fertilization, showing the highest percentage increase at the beginning of plant regrowth: aliphatic GLS increased by 150 % with N alone and 400 % with N and S supply, while aromatics and indoles increased both up to 35 % with N alone and 280 and 180 % with N and S, respectively. The results suggest that fertilization led to modulate GLS content and composition in plants in relation to a specific employment.

ACS Style

Susanna De Maria; Rosa Agneta; Filomena Lelario; Christian Möllers; Anna Rita Rivelli. Influence of nitrogen and sulfur fertilization on glucosinolate content and composition of horseradish plants harvested at different developmental stages. Acta Physiologiae Plantarum 2016, 38, 1 -12.

AMA Style

Susanna De Maria, Rosa Agneta, Filomena Lelario, Christian Möllers, Anna Rita Rivelli. Influence of nitrogen and sulfur fertilization on glucosinolate content and composition of horseradish plants harvested at different developmental stages. Acta Physiologiae Plantarum. 2016; 38 (4):1-12.

Chicago/Turabian Style

Susanna De Maria; Rosa Agneta; Filomena Lelario; Christian Möllers; Anna Rita Rivelli. 2016. "Influence of nitrogen and sulfur fertilization on glucosinolate content and composition of horseradish plants harvested at different developmental stages." Acta Physiologiae Plantarum 38, no. 4: 1-12.

Review
Published: 01 March 2016 in Toxins
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Only a small percentage of insect species are pests. However, pest species cause significant losses in agricultural and forest crops, and many are vectors of diseases. Currently, many scientists are focused on developing new tools to control insect populations, including secondary plant metabolites, e.g., alkaloids, glycoalkaloids, terpenoids, organic acids and alcohols, which show promise for use in plant protection. These compounds can affect insects at all levels of biological organization, but their action generally disturbs cellular and physiological processes, e.g., by altering redox balance, hormonal regulation, neuronal signalization or reproduction in exposed individuals. Secondary plant metabolites cause toxic effects that can be observed at both lethal and sublethal levels, but the most important effect is repellence. Plants from the Solanaceae family, which contains numerous economically and ecologically important species, produce various substances that affect insects belonging to most orders, particularly herbivorous insects and other pests. Many compounds possess insecticidal properties, but they are also classified as molluscides, acaricides, nematocides, fungicides and bactericides. In this paper, we present data on the sublethal and lethal toxicity caused by pure metabolites and crude extracts obtained from Solanaceae plants. Pure substances as well as water and/or alcohol extracts cause lethal and sublethal effects in insects, which is important from the economical point of view. We discuss the results of our study and their relevance to plant protection and management.

ACS Style

Szymon Chowański; Zbigniew Adamski; Paweł Marciniak; Grzegorz Rosiński; Ender Büyükgüzel; Kemal Büyükgüzel; Patrizia Falabella; Laura Scrano; Emanuela Ventrella; Filomena Lelario; Sabino A. Bufo. A Review of Bioinsecticidal Activity of Solanaceae Alkaloids. Toxins 2016, 8, 60 .

AMA Style

Szymon Chowański, Zbigniew Adamski, Paweł Marciniak, Grzegorz Rosiński, Ender Büyükgüzel, Kemal Büyükgüzel, Patrizia Falabella, Laura Scrano, Emanuela Ventrella, Filomena Lelario, Sabino A. Bufo. A Review of Bioinsecticidal Activity of Solanaceae Alkaloids. Toxins. 2016; 8 (3):60.

Chicago/Turabian Style

Szymon Chowański; Zbigniew Adamski; Paweł Marciniak; Grzegorz Rosiński; Ender Büyükgüzel; Kemal Büyükgüzel; Patrizia Falabella; Laura Scrano; Emanuela Ventrella; Filomena Lelario; Sabino A. Bufo. 2016. "A Review of Bioinsecticidal Activity of Solanaceae Alkaloids." Toxins 8, no. 3: 60.

Articles
Published: 20 July 2015 in Journal of Environmental Science and Health, Part A
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Stability and removal of spironolactone (SP) from wastewater produced at Al-Quds University Campus were investigated. Kinetic studies on both pure water and wastewater coming from secondary treatment (activated sludge) demonstrated that the potassium-sparing diuretic (water pill), spironolactone, underwent degradation to its hydrolytic derivative, canrenone, in both media. The first-order hydrolysis rate of SP in activated sludge at 25°C (3.80 × 10−5 s−1) was about 49-fold larger than in pure water (7.4 × 10−7 s−1). The overall performance of the wastewater treatment plant (WWTP) installed in the University Campus was assessed showing that more than 90% of spiked SP was removed together with its newly identified metabolites. In order to look for a technology to supplement or replace ultra-filtration membranes, the effectiveness of adsorption and filtration by micelle-clay filters for removing SP was tested in comparison with activated charcoal. Batch adsorption in aqueous suspensions was well described by Langmuir isotherms, showing a better removal by the micelle-clay material. Filtration of SP water solutions by columns filled with a mixture of sand and a micelle-clay complex showed complete removal of the drug at concentrations higher than in sand/activated-charcoal filled filters.

ACS Style

Saleh Sulaiman; Mustafa Khamis; Shlomo Nir; Filomena Lelario; Laura Scrano; Sabino A. Bufo; Rafik Karaman. Stability and removal of spironolactone from wastewater. Journal of Environmental Science and Health, Part A 2015, 50, 1127 -1135.

AMA Style

Saleh Sulaiman, Mustafa Khamis, Shlomo Nir, Filomena Lelario, Laura Scrano, Sabino A. Bufo, Rafik Karaman. Stability and removal of spironolactone from wastewater. Journal of Environmental Science and Health, Part A. 2015; 50 (11):1127-1135.

Chicago/Turabian Style

Saleh Sulaiman; Mustafa Khamis; Shlomo Nir; Filomena Lelario; Laura Scrano; Sabino A. Bufo; Rafik Karaman. 2015. "Stability and removal of spironolactone from wastewater." Journal of Environmental Science and Health, Part A 50, no. 11: 1127-1135.

Articles
Published: 14 July 2015 in DESALINATION AND WATER TREATMENT
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In this study, the stability of chlorpyrifos, a known pesticide, in fresh water and sludge was investigated. The results showed that chlorpyrifos underwent hydrolysis in both media to give two main metabolites: 3,5,6-trichoro-2-pyridiniol (TCP) and diethylthiophosphoric acid (DETP). The hydrolysis reaction in both media was found to follow first-order kinetics with a rate constant of 7.10 × 10−8 (R2 = 0.999) in pure water and of 9.30 × 10−8 (R2 = 0.996) in sludge. Chlorpyrifos degradation’s half-life value in pure water was 112 d and in sludge was 85.9 d. The efficiency of Al-Quds University wastewater treatment plant demonstrated that the ultrafiltration-hollow fiber unit (UF-HF) was insufficient in removing chlorpyrifos from spiked secondary treated wastewater samples, whereas the combination of ultrafiltration-spiral wound unit (UF-SW) followed by activated carbon (AC) column was quite efficient and yielded a complete removal of the pesticide. Batch adsorption experiments using either AC or micelle–clay complex were performed and the experimental results were fitted to Langmuir and Freundlich isotherms. Adsorption analysis using Langmuir isotherm revealed that Qmax for the AC was higher than that of the micelle–clay complex, while Freundlich isotherm showed almost similar values of n (3.413 vs. 3.745) for both adsorbents, despite the fact that the activated carbon filter showed higher kF value. Filtration column of mixed micelle–clay complex and sand demonstrated a breakthrough point after the third fraction for chlorpyrifos removal and a complete removal for all fractions collected in the TCP experiment. This result reveals that mixed micelle–clay complex and sand column is much more efficient in removing TCP than removing its parent compound, chlorpyrifos.

ACS Style

Mohannad Qurie; Mustafa Khamis; Ibrahim Ayyad; Laura Scrano; Filomena Lelario; Sabino Aurelio Bufo; Gennaro Mecca; Rafik Karaman. Removal of chlorpyrifos using micelle–clay complex and advanced treatment technology. DESALINATION AND WATER TREATMENT 2015, 57, 15687 -15696.

AMA Style

Mohannad Qurie, Mustafa Khamis, Ibrahim Ayyad, Laura Scrano, Filomena Lelario, Sabino Aurelio Bufo, Gennaro Mecca, Rafik Karaman. Removal of chlorpyrifos using micelle–clay complex and advanced treatment technology. DESALINATION AND WATER TREATMENT. 2015; 57 (33):15687-15696.

Chicago/Turabian Style

Mohannad Qurie; Mustafa Khamis; Ibrahim Ayyad; Laura Scrano; Filomena Lelario; Sabino Aurelio Bufo; Gennaro Mecca; Rafik Karaman. 2015. "Removal of chlorpyrifos using micelle–clay complex and advanced treatment technology." DESALINATION AND WATER TREATMENT 57, no. 33: 15687-15696.

Articles
Published: 29 June 2015 in Environmental Technology
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Atorvastatin (ATO), rosuvastatin (RST) and simvastatin (SIM) are commonly used drugs that belong to the statin family (lowering human blood cholesterol levels) and have been detected as contaminants in natural waters. Stability and removal of ATO, RST and SIM from spiked wastewater produced at the Al-Quds University campus were investigated. All three statins were found to undergo degradation in wastewater (activated sludge). The degradation reactions of the three drugs in wastewater at room temperature follow first-order kinetics with rate constants of 2.2 × 10−7 s−1 (ATO), 1.8 × 10−7 s−1 (RST) and 1.8 × 10−6 s−1 (SIM), which are larger than those obtained in pure water under the same conditions, 1.9 × 10−8 s−1 (ATO), 2.2 × 10−8 s−1 (RST) and 6.2 × 10−7 s−1 (SIM). Degradation products were identified by LC-MS and LC/MS/MS. The overall performance of the wastewater treatment plant (WWTP) installed in the Al-Quds University campus towards the removal of these drugs was assessed showing that more than 90% of spiked ATO, RST and SIM were removed. In order to evaluate the efficiency of alternative removal methods to replace ultra-filtration membranes, adsorption isotherms for the three statins were investigated using both activated carbon and clay–micelle complex as adsorbents. The batch adsorption isotherms for the three statins were found to fit the Langmuir equation, with a larger number of adsorption sites and binding affinity for micelle–clay composite compared with activated carbon and filtration experiments of the three statins and their corresponding metabolites demonstrated a more efficient removal by micelle–clay filters.

ACS Style

Saleh Sulaiman; Mustafa Khamis; Shlomo Nir; Filomena Lelario; Laura Scrano; Sabino Aurelio Bufo; Gennaro Mecca; Rafik Karaman. Stability and removal of atorvastatin, rosuvastatin and simvastatin from wastewater. Environmental Technology 2015, 36, 3232 -3242.

AMA Style

Saleh Sulaiman, Mustafa Khamis, Shlomo Nir, Filomena Lelario, Laura Scrano, Sabino Aurelio Bufo, Gennaro Mecca, Rafik Karaman. Stability and removal of atorvastatin, rosuvastatin and simvastatin from wastewater. Environmental Technology. 2015; 36 (24):3232-3242.

Chicago/Turabian Style

Saleh Sulaiman; Mustafa Khamis; Shlomo Nir; Filomena Lelario; Laura Scrano; Sabino Aurelio Bufo; Gennaro Mecca; Rafik Karaman. 2015. "Stability and removal of atorvastatin, rosuvastatin and simvastatin from wastewater." Environmental Technology 36, no. 24: 3232-3242.