Kamalinder K Singh

Prof. Kamalinder K Singh

School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, Lancashire, UK
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Research Focus & Metrics

Academic Career Length

21Years (2006-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2008 in International Journal of Pharmaceutics
Verified
Journal Article
Closed access
Kamalinder K SinghKamalinder K Singh
Kamalinder K Singh
SVSharvani K. Vingkar
Sharvani K. Vingkar

1 December 2006 in AAPS PharmSciTech
Verified
Journal Article
Closed access
PDF file
PPPallavi V. Pople
Pallavi V. Pople
Kamalinder K SinghKamalinder K Singh
Kamalinder K Singh

1 September 2011 in International Journal of Pharmaceutics
Verified
Journal Article
Closed access
RSR. Shegokar
R. Shegokar
Kamalinder K SinghKamalinder K Singh
Kamalinder K Singh
RMR.H. Müller
R.H. Müller

1 October 2010 in International Journal of Pharmaceutics
Verified
Journal Article
Closed access
PPPallavi V. Pople
Pallavi V. Pople
Kamalinder K SinghKamalinder K Singh
Kamalinder K Singh

1 September 2011 in European Journal of Pharmaceutics and Biopharmaceutics
Verified
Journal Article
Closed access
PPPallavi V. Pople
Pallavi V. Pople
Kamalinder K SinghKamalinder K Singh
Kamalinder K Singh

7 January 2013 in Expert Opinion on Drug Delivery
Verified
Journal Article
Closed access
MPMedha Patel
Medha Patel
Eliana B. SoutoEliana B. Souto
Eliana B. Souto
Kamalinder K SinghKamalinder K Singh
Kamalinder K Singh
Introduction: With the advancement in the field of medical colloids and interfacial sciences, the life expectancy has been greatly improved. In addition, changes in the human lifestyle resulted in development of various organic and functional disorders. Central nervous system (CNS) disorders are most prevalent and increasing among population worldwide. The neurological disorders are multi-systemic and difficult to treat as portal entry to brain is restricted on account of its anatomical and physiological barrier. Areas covered: The present review discusses the limitations to CNS drug delivery, and the various approaches to bypass the blood brain barrier (BBB), focusing on the potential use of solid lipid nanoparticles (SLN) for drug targeting to brain. The methods currently in use for SLN production, physicochemical characterization and critical issues related to the formulation development suitable for targeting brain are also discussed. Expert opinion: The potential advantages of the use of SLN over polymeric nanoparticles are due to their lower cytotoxicity, higher drug loading capacity and scalability. In addition, their production is cost effective and the systems provide a drug release in a controlled manner up to several weeks. Drug targeting potential of SLN can be enhanced by attaching ligands to their surface.