In this paper, a stochastic model (with random noise transmission) is designed. The model possesses substantial potential to describe the dynamical behavior of the Hepatitis B (HBV) virus and it’s control by applying the strategy of vaccinating an offspring. The number of basic reproductive is calculated and proved that the system holds some sharp threshold properties. It is investigated that the model has a bounded, unique and positive solution subject to initial positive data. Furthermore, the stability of the investigated system has been presented by using stochastic Lyapunov functional theory. Stationary distribution and extinction of the infection are examined by providing sufficient conditions. To control the spread of the disease through some external measures, we used optimal control theory and analyzed stochastic as well as deterministic control problems. For further verification of the obtained analytical results, additional graphical solutions have been presented for the ease of understanding. This study may provide a strong theoretical basis for understanding worldwide chronic infectious diseases.

In the history of the world, contagious diseases have been proved to pose serious threats to humanity that needs uttermost research in the field and its prompt implementations. With this motive, an attempt has been made to investigate the spread of such contagion by using a delayed stochastic epidemic model with general incidence rate, time-delay transmission, and the concept of cross immunity. It is proved that the system is mathematically and biologically well-posed by showing that there exist a positive and bounded global solution of the model. Necessary conditions are derived, which guarantees the permanence as well as extinction of the disease. The model is further investigated for the existence of an ergodic stationary distribution and established sufficient conditions. The non-zero periodic solution of the stochastic model is analyzed quantitatively. The analysis of optimality and time delay is used, and a proper strategy was presented for prevention of the disease. A scheme for the numerical simulations is developed and implemented in MATLAB, which reflects the long term behavior of the model. Simulation suggests that the noises play a vital role in controlling the spread of an epidemic following the proposed flow, and the case of disease extinction is directly proportional to the magnitude of the white noises. Since time delay reflects the dynamics of recurring epidemics, therefore, it is believed that this study will provide a robust basis for studying the behavior and mechanism of chronic infections.

Monkeypox 2022, a new re-emerging disease, is caused by the Monkeypox virus. Structurally, this virus is related to the smallpox virus and infects the host in a similar way; however, the symptoms of Monkeypox are more severe. In this research work, a mathematical model for understanding the dynamics of Monkeypox 2022 is suggested that takes into account two modes of transmission: horizontal human dissemination and cross-infection between animals and humans. Due to lack of substantial knowledge about the virus diffusion and the effect of external perturbations, the model is extended to the probabilistic formulation with Lévy jumps. The proposed model is a two block compartmental system that requires the form of Itô-Lévy stochastic differential equations. Based on some assumptions and nonstandard analytical techniques, two principal asymptotic properties are proved: the eradication and continuation in the mean of Monkeypox 2022. The outcomes of the study reveals that the dynamical behavior of the proposed Monkeypox 2022 system is chiefly governed by some parameters that are precisely correlated with the noise intensities. To support the obtained theoretical finding, examples based on numerical simulations and real data are presented at the end of the study. The numerical simulations also exhibit the impact of the innovative adopted mathematical techniques on the findings of this work.