Denis Bourgeois

Prof. Dr. Denis Bourgeois

Professor of Public Health, Systemic Healthcare Laboratory EA 4129, Faculty of Medicine Laennec, University of Lyon, France
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Research Focus & Metrics

Academic Career Length

42Years (1985-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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30 September 2005
Verified
Journal Article
Closed access
PPPoul Erik Petersen
Poul Erik Petersen
Denis BourgeoisDenis Bourgeois
Denis Bourgeois
HOHiroshi Ogawa
Hiroshi Ogawa
SESaskia Estupinan-Day
Saskia Estupinan-Day
CNCharlotte Ndiaye
Charlotte Ndiaye

1 November 2013 in Journal of Dentistry
Verified
Journal Article
Closed access
DBD.W. Bartlett
D.W. Bartlett
ALA. Lussi
A. Lussi
NWN.X. West
N.X. West
BPBouchard Philippe
Bouchard Philippe
Mariano SanzMariano Sanz
Mariano Sanz
Denis BourgeoisDenis Bourgeois
Denis Bourgeois

1 October 2013 in Journal of Dentistry
Verified
Journal Article
Closed access
NWNicola Xania West
Nicola Xania West
MSMariano Sanz
Mariano Sanz
ALAdrian Lussi
Adrian Lussi
DBDavid Bartlett
David Bartlett
BPBouchard Philippe
Bouchard Philippe
Denis BourgeoisDenis Bourgeois
Denis Bourgeois

13 January 2020 in Nanomaterials
Verified
Journal Article
Open access
PDF file
Florence CarrouelFlorence Carrouel
Florence Carrouel
SVStephane Viennot
Stephane Viennot
LOLivia Ottolenghi
Livia Ottolenghi
CGCédric Gaillard
Cédric Gaillard
Denis BourgeoisDenis Bourgeois
Denis Bourgeois
Many investigations have pointed out widespread use of medical nanosystems in various domains of dentistry such as prevention, prognosis, care, tissue regeneration, and restoration. The progress of oral medicine nanosystems for individual prophylaxis is significant for ensuring bacterial symbiosis and high-quality oral health. Nanomaterials in oral cosmetics are used in toothpaste and other mouthwash to improve oral healthcare performance. These processes cover nanoparticles and nanoparticle-based materials, especially domains of application related to biofilm management in cariology and periodontology. Likewise, nanoparticles have been integrated in diverse cosmetic produces for the care of enamel remineralization and dental hypersensitivity. This review summarizes the indications and applications of several widely employed nanoparticles in oral cosmetics, and describes the potential clinical implementation of nanoparticles as anti-microbial, anti-inflammatory, and remineralizing agents in the prevention of dental caries, hypersensitivity, and periodontitis.

9 October 2019 in Microorganisms
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Journal Article
Open access
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Denis BourgeoisDenis Bourgeois
Denis Bourgeois
CICamille Inquimbert
Camille Inquimbert
LOLivia Ottolenghi
Livia Ottolenghi
Florence CarrouelFlorence Carrouel
Florence Carrouel
Cardiovascular diseases, chronic obstructive pulmonary diseases, diabetes, rheumatoid arthritis, and cancer are the most common noncommunicable diseases (NCDs). These NCDs share risk factors with periodontal disease (PD), a preventable risk factor linked to lifestyle. The discussion regarding the association between these chronic diseases is more complex. There is still a significant knowledge gap particularly of the causal relationship between PD and NCDs. In this paper, we present fundamental knowledge of the mechanisms and roles of putative periodontal bacteria to gather several hypotheses, evidence that clinical studies thus far have not produced. Although the causal hypotheses are not yet clearly established on a biological basis, prevention and prophylactic measures are recommended to prevent even the possibility of such potential risk factors.

7 January 2021 in Journal of Clinical Medicine
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Journal Article
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PMPrescilla Martinon
Prescilla Martinon
LFLaurie Fraticelli
Laurie Fraticelli
AGAgnès Giboreau
Agnès Giboreau
CDClaude Dussart
Claude Dussart
Denis BourgeoisDenis Bourgeois
Denis Bourgeois
Florence CarrouelFlorence Carrouel
Florence Carrouel
Nutrition is recognized as an essential component in the prevention of a number of chronic diseases, including periodontal disease. Based on these considerations, a better understanding is required regarding how the diet, and more particularly the intake of macronutrients and micronutrients, could impact the potential relationship between nutrition and periodontal diseases, periodontal diseases and chronic diseases, nutrition and chronic diseases. To overcome this complexity, an up-to-date literature review on the nutriments related to periodontal and chronic diseases was performed. High-sugar, high-saturated fat, low-polyols, low-fiber and low-polyunsaturated-fat intake causes an increased risk of periodontal diseases. This pattern of nutrients is classically found in the Western diet, which is considered as an ‘unhealthy’ diet that causes cardiovascular diseases, diabetes and cancers. Conversely, low-sugar, high-fiber and high-omega-6-to-omega-3 fatty acid ratio intake reduces the risk of periodontal diseases. The Mediterranean, DASH, vegetarian and Okinawa diets that correspond to these nutritional intakes are considered as ‘healthy’ diets, reducing this risk of cardiovascular diseases, diabetes and cancers. The role of micronutrients, such as vitamin D, E, K and magnesium, remains unclear, while others, such as vitamin A, B, C, calcium, zinc and polyphenols have been shown to prevent PDs. Some evidence suggests that probiotics and prebiotics could promote periodontal health. Periodontal and chronic diseases share, with a time delay, nutrition as a risk factor. Thus, any change in periodontal health should be considered as a warning signal to control the dietary quality of patients and thus reduce the risk of developing chronic diseases later on.