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A short introduction to survival analysis and censored data is included in this paper. A thorough literature review in the field of cure models has been done. An overview on the most important and recent approaches on parametric, semiparametric and nonparametric mixture cure models is also included. The main nonparametric and semiparametric approaches were applied to a real time dataset of COVID-19 patients from the first weeks of the epidemic in Galicia (NW Spain). The aim is to model the elapsed time from diagnosis to hospital admission. The main conclusions, as well as the limitations of both the cure models and the dataset, are presented, illustrating the usefulness of cure models in this kind of studies, where the influence of age and sex on the time to hospital admission is shown.
Maria Pedrosa-Laza; Ana López-Cheda; Ricardo Cao. Cure models to estimate time until hospitalization due to COVID-19. Applied Intelligence 2021, 1 -14.
AMA StyleMaria Pedrosa-Laza, Ana López-Cheda, Ricardo Cao. Cure models to estimate time until hospitalization due to COVID-19. Applied Intelligence. 2021; ():1-14.
Chicago/Turabian StyleMaria Pedrosa-Laza; Ana López-Cheda; Ricardo Cao. 2021. "Cure models to estimate time until hospitalization due to COVID-19." Applied Intelligence , no. : 1-14.
In order to enlarge the shelf life and avoid the waste of fresh-cut (FC) products, novel packaging techniques with antimicrobial properties have been proposed. In this work, we analyzed the potential environmental benefits of using films reinforced with bactericidal ZnO nanoparticles (NP) for FC produce packaging, when compared to the traditional polypropylene (PP) films. A biodegradable, polylactic acid (PLA) package and a non-biodegradable, polypropylene package, both coated with ZnO NP, were considered as novel technologies. The eco-profile of the considered alternatives was assessed via two life cycle assessments (LCAs). Firstly, an attributional LCA was performed in order to compare the materials in terms of their production and end of life (EOL) processes, allowing us to extend the conclusions to different food products. Secondly, a consequential LCA was performed taking into account the whole life cycle of the fresh vegetable, with special attention to the environmental implications of the produce losses among the chain. The uncertainties of the models were assessed via Monte Carlo approach. In both cases, the scenarios concerning the PLA and PP active packages with ZnO NP showed a better profile than the traditional techniques, specifically when considering the full supply chain of the FC vegetables in the consequential LCA. As agricultural production is the main contributor to the environmental impact of the cycle, the avoidance of wastes by extending the shelf life through the novel packages leads to the impact reduction of FC products.
Miguel Vigil; Maria Pedrosa-Laza; Jv Alvarez Cabal; Francisco Ortega-Fernández. Sustainability Analysis of Active Packaging for the Fresh Cut Vegetable Industry by Means of Attributional & Consequential Life Cycle Assessment. Sustainability 2020, 12, 7207 .
AMA StyleMiguel Vigil, Maria Pedrosa-Laza, Jv Alvarez Cabal, Francisco Ortega-Fernández. Sustainability Analysis of Active Packaging for the Fresh Cut Vegetable Industry by Means of Attributional & Consequential Life Cycle Assessment. Sustainability. 2020; 12 (17):7207.
Chicago/Turabian StyleMiguel Vigil; Maria Pedrosa-Laza; Jv Alvarez Cabal; Francisco Ortega-Fernández. 2020. "Sustainability Analysis of Active Packaging for the Fresh Cut Vegetable Industry by Means of Attributional & Consequential Life Cycle Assessment." Sustainability 12, no. 17: 7207.
Fresh-cut vegetables, namely those that undergo processes such as washing, sorting, or chopping while keeping their fresh state, constitute an important market element nowadays. Among those operations, the washing step becomes really important due both to the extensive use of water resources and to the utilization of controversial water sanitizing agents, such as chlorine. To ideally eliminate those chlorinated compounds while decreasing water consumption, four novel filtrating technologies (pulsed corona discharge combined with nanofiltration, NF-PCD; classical ultrafiltration, UF; nanofiltration membranes integrating silver nanoparticles, NF-AgNP; and microfiltration with cellulose acetate membranes containing chitin nanocrystals, ChCA) have been proposed to eliminate any contaminating agent in recirculated water. Here, we performed a life cycle assessment (LCA) to assess the environmental effects of introducing these new solutions and to compare those impacts with the burden derived from the current strategy. The novel technologies showed a decreased environmental burden, mainly due to the enhanced water recirculation and the subsequent decrease in energy consumption for pumping and cooling the water stream. The environmental gain would be maintained even if a certain amount of chlorine was still needed. This analysis could serve as an aid to decision-making while evaluating the introduction of new sanitizing techniques.
Miguel Vigil; Maria Pedrosa Laza; Henar Moran-Palacios; Jv Alvarez Cabal. Optimizing the Environmental Profile of Fresh-Cut Produce: Life Cycle Assessment of Novel Decontamination and Sanitation Techniques. Sustainability 2020, 12, 3674 .
AMA StyleMiguel Vigil, Maria Pedrosa Laza, Henar Moran-Palacios, Jv Alvarez Cabal. Optimizing the Environmental Profile of Fresh-Cut Produce: Life Cycle Assessment of Novel Decontamination and Sanitation Techniques. Sustainability. 2020; 12 (9):3674.
Chicago/Turabian StyleMiguel Vigil; Maria Pedrosa Laza; Henar Moran-Palacios; Jv Alvarez Cabal. 2020. "Optimizing the Environmental Profile of Fresh-Cut Produce: Life Cycle Assessment of Novel Decontamination and Sanitation Techniques." Sustainability 12, no. 9: 3674.