Objective: In this study, we bibliometrically evaluated the top 100 cited articles on urological emergencies published since 1975 with a multidisciplinary and interdisciplinary perspective. Material and methods: We obtained the data for this study from the Thomson Reuters Web of Science and PubMed. We determined 360 articles which were related directly or indirectly to urological emergencies between 1975 and 2017 and analyzed retrospectively the top 100 cited articles among these. Results: The mean citation impact factor of the top 100 cited articles was 25.8±50.1 (range: 4-467) between 1991 and 2014. We determined that classical articles were cited for 2588 times and the total number of self-citations was 23 (0.8%). Highest publication rate per year was in 2006 (n=9). Among the institutions which published ≥2 articles per year University of Texas led the way with 5 articles. The top 100 articles came from 27 countries and 58% of these are from the USA (n=29), the United Kingdom (n=23) and Germany (n=6). For the top 3 journals of the 33 of top 100 articles most frequently cited were published in journals with an impact factor ≥2 namely, Journal of Urology (n=15), British Journal of Urology International (n=13) and Urology (n=5) respectively. The most frequently cited main topics were penile emergencies with 22 articles and acute scrotal problems with 15 articles. Most of the classical articles on urological emergencies were based on clinical researches (n=95) and also we found that the average level of evidence for the top 100 cited articles was 4.16 (range: 1-5). Mostly preferred publishing language was English among this scientific papers (n=90). Conclusion: Although not considered as a completely unbiased and adequate criterion for scientific evaluations, analysis of the top 100 cited articles provides us with important current data on urological emergencies. Cite this article as: Kazımoğlu H, Dokur M. The top 100 cited articles on urological emergencies: A bibliometric analysis. Turk J Urol 2018; 44(3): 239-50.

Objective: Infections play an important part in post-transplantation causes of morbidity and mortality. The purpose of this study is to evaluate short-, and long-term infections encountered in after renal transplantations. Material and methods: Two hundred and thirteen cases that consisted of both living and cadaver donors, who suffered from late period renal insufficiency and had renal transplant between June 2011 and January 2016 at the Transplantation Center of Sanko University School of Medicine were included in the study. In this study the short-, and long-term infections seen in post renal transplantation were examined retrospectively. Infection types, frequency and periods of infection, infection agents and predisposing factors were determined as the examination parameters. Results: Of the 213 patients who received renal transplant, 139 were males (65.3%) and 74 were women (34.75%) and the mean age was 42±11,8 (range, 14-70) years. Twelve (5.6%) patients exited after renal transplantation. Post-transplant infections were seen in 49 patients (23.1%) within 1-6 months; in 13 patients (6.1%) within 6-12 months; and in 5 patients (2.4%) after the 12th month. The most common infections after renal transplantation were associated with urinary tract (70 patients, 34.3%). The most frequently isolated agents were E. coli (n=66; 30.9%), Kebsiella spp. (n=18; 8.4%) and Enterococci (n=18; 8.4%) respectively. The renal transplants from the cadavers were observed to contract infections 1.78 times more frequently compared to the living donors (OR=1.78, 95% CI=1.03-3.09). Conclusion: The most common complication after renal transplantation are infections. The majority of the infections are seen within the first year especially between 1-6 months. Post-transplant infections are often related to urinary system. E.coli is the most frequently isolated agent and it may be responsible for urosepsis in renal transplant patients. Infection more often seen in renal transplantations from cadavers. Cite this article as: Kazımoğlu H, Harman R, Mercimek MN, Dokur M, Uysal E. Evaluation of early and late-term infections after renal transplantation: Clinical experiences of Sanko University Medical Faculty Transplantation Center. Turk J Urol 2019; 45(1): 63-9.

Evaluation of the relationship between neutrophil lymphocyte ratio and the most common bacterial urinary tract infections after transplantation

Objective: In recent years, the number of infertile couples who desire pregnancy with assisted reproduction techniques is increasing. Smoking and alcohol consumption are important factors affecting the treatment of fertility and assisted reproductive techniques. To evaluate the effect of smoking and alcohol consumption on spermiogram results.Study Design: This prospective case-control study was conducted at current urology and infertility department in a tertiary research hospital and a total of 6171 cases included in the study. Data collected and evaluated were age and sperm parameters (liquefaction, semen volume, sperm concentration, total number, total motility, progressive motility, slow motility, non-progressive motility, morphology). Results: Of 6171 patients; a total of 3247 men was smoker (n:3247, %52.6) and 3511 was alcohol users (n:3511, %56.9). Mean age of the patients in the study group was 32.8±6.5 years. There was a statistically significant difference between the smoker and nonsmoker in terms of sperm concentration and slow motility (p <0.05). There was a statistically significant difference between alcohol consumption and no alcohol consumption in terms of; semen volume, sperm concentration, normal morphology (p <0.05).Conclusion: According to this study, smoking has a negative effect on sperm concentration and slow motility. Alcohol consumption has a negative impact on semen volume, sperm concentration, normal morphology. Smoking and alcohol consumption separately and combined were found to have a deleterious effect on sperm parameters. It is suggested that both habits may contribute to infertility problems.

En tr Prostate cancer is a common type of cancer among men. Recently, studies on new anticancer agents of herbal origin in the treatment of cancer have increased. Haplophyllum buxbaumii (HP) is a perennial herbaceous plant. Studies have reported that Haplophyllum subspecies has antioxidant properties. And the anticancer effect of HP is unknown. This study aims to reveal the apoptotic effect HP on prostate cancer. The cytotoxic effect of HP was evaluated by the MTT method. In addition, apoptotic pathway mediators were analyzed by ELISA method. HP extract application reduced the viability of prostate cancer and activated the apoptotic mediators while decreasing anti-apoptotic mediators. Our study showed that HP extract has an antiproliferative and apoptotic effect on prostate cancer. Prostat kanseri, erkekler arasında yaygın bir kanser türüdür. Son zamanlarda, kanser tedavisinde bitkisel kökenli yeni antikanser ajanlar üzerine yapılan çalışmalar artmıştır. Haplophyllum buxbaumii (HP) çok yıllık otsu bir bitkidir. Çalışmalar, Haplophyllum alt türlerinin antioksidan özelliklere sahip olduğunu bildirmiştir. HP'nin antikanser etkisi bilinmemektedir. Bu çalışma, HP'nin prostat kanseri üzerindeki apoptotik etkisini ortaya çıkarmayı amaçlamaktadır. HP'nin sitotoksik etkisi MTT yöntemi ile değerlendirildi. Ayrıca apoptotik yol aracı medyatörleri ELISA yöntemi ile analiz edildi. HP ekstresi uygulaması, prostat kanserinin canlılığını azalttı ve apoptotik medyatörleri aktive ederken, anti-apoptotik mediyatörleri azalttı. Çalışmamız, HP ekstresinin prostat kanseri üzerinde antiproliferatif ve apoptotik bir etkiye sahip olduğunu gösterdi.