Shijie Xu

Dr. Shijie Xu

Tianjin Key Laboratory of Brine Chemical Engineering and Ecological Utilization of Resources, Tianjin Engineering Center of Marine Chemical Engineering & Technology, College of Chemical Engineering and Materials Science, Tianjin University of Science and Technology, Tianjin 300457, China
orcid

Research Focus & Metrics

Academic Career Length

13Years (2014-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 June 2017 in Engineering
Verified
Journal Article
Open access
DZDejiang Zhang
Dejiang Zhang
SXShijie Xu
Shijie Xu
Shichao DuShichao Du
Shichao Du
JWJingkang Wang
Jingkang Wang
JGJunbo Gong
Junbo Gong
Crystallization is an important unit operation in the pharmaceutical industry. At present, most pharmaceutical crystallization processes are performed in batches. However, due to product variability from batch to batch and to the low productivity of batch crystallization, continuous crystallization is gaining increasing attention. In the past few years, progress has been made to allow the products of continuous crystallization to meet different requirements. This review summarizes the progress in pharmaceutical continuous crystallization from a product engineering perspective. The advantages and disadvantages of different types of continuous crystallization are compared, with the main difference between the two main types of crystallizers being their difference in residence time distribution. Approaches that use continuous crystallization to meet different quality requirements are summarized. Continuous crystallization has advantages in terms of size and morphology control. However, it also has the problem of a process yield that may be lower than that of a batch process, especially in the production of chirality crystals. Finally, different control strategies are compared

4 February 2019 in Chemistry of Materials
Verified
Journal Article
Closed access
YCYifu Chen
Yifu Chen
BYBo Yu
Bo Yu
YCYingdan Cui
Yingdan Cui
SXShijie Xu
Shijie Xu
Junbo GongJunbo Gong
Junbo Gong

20 September 2020 in Industrial & Engineering Chemistry Research
Verified
Journal Article
Closed access
SXShijie Xu
Shijie Xu
ZHZhongbi Hou
Zhongbi Hou
XCXiaoyu Chuai
Xiaoyu Chuai
YWYanfei Wang
Yanfei Wang

18 November 2021 in Crystal Growth & Design
Verified
Journal Article
Closed access
SXShijie Xu
Shijie Xu
DCDi Cao
Di Cao
YLYixuan Liu
Yixuan Liu
YWYanfei Wang
Yanfei Wang

24 February 2021 in Crystal Growth & Design
Verified
Journal Article
Closed access
SXShijie Xu
Shijie Xu
HZHuimin Zhang
Huimin Zhang
BQBige Qiao
Bige Qiao
YWYanfei Wang
Yanfei Wang

2 November 2016 in Journal of Chemical & Engineering Data
Verified
Journal Article
Closed access
SJShuang Jiang
Shuang Jiang
YQYujia Qin
Yujia Qin
SWSonggu Wu
Songgu Wu
SXShijie Xu
Shijie Xu
KLKangli Li
Kangli Li
Junbo GongJunbo Gong
Junbo Gong