Giedre Krenciute is a faculty member in the Department of Bone Marrow Transplantation and Cellular Therapy at St Jude Children’s Research Hospital. She received her Ph.D. in Biochemistry and Molecular Biology at Baylor College of Medicine (BCM), followed by post-doctoral training in the Center for Cell and Gene Therapy at BCM. The major focus of her laboratory is to develop an effective immunotherapy for pediatric brain tumors using genetically modified T cells. Research areas include generating and optimizing CAR T-cells to target brain tumor-associated antigens, enhancing CAR T-cell effector functions by different next-generation genetic manipulations, and understanding tumor escape mechanisms to design superior immunotherapy-based treatments.