Sachio Takeno received his M.D. from Kyoto University in 1987, and subsequently earned his Ph.D. in Medicine from Hiroshima University. He has been serving as a Professor in the Graduate School of Biomedical and Health Sciences (Medical Sciences), Hiroshima University, where he conducts both clinical and basic research in otolaryngology.He is involved in the clinical management of patients with a broad spectrum of diseases of the ear, nose, and throat, including allergic and inflammatory disorders as well as complex surgical cases. His clinical work emphasizes improved treatment outcomes for refractory otolaryngologic conditions using advanced diagnostic and therapeutic techniques.His research topics mainly include allergic rhinologic disease mechanisms, eosinophilic inflammation, nitric oxide function in sinonasal mucosa, and innovative surgical and therapeutic approaches for chronic sinusitis and middle ear pathology.