Recent years have seen tremendous progress in the theoretical understanding of quantum systems driven dissipatively by coupling to different baths at their edges. This was possible because of concurrent advances in the models used to represent these systems, the methods employed, and the analysis of the emerging phenomenology. A comprehensive review of these three integrated research directions is given. First provided is an overarching view of the models of boundary-driven open quantum systems, in both the weak- and strong-coupling regimes. This is followed by a review of state-of-the-art analytical and numerical methods that are exact, perturbative, and approximate. Finally, the transport properties of some paradigmatic one-dimensional chains are discussed, with an emphasis on disordered and quasiperiodic systems, the emergence of rectification and negative differential conductance, and the role of phase transitions, and an outlook on further research options is given.

We present a physical implementation of a Maxwell demon which consists of a conventional single electron transistor (SET) capacitively coupled to another quantum dot detecting its state. Altogether, the system is described by stochastic thermodynamics. We identify the regime where the energetics of the SET is not affected by the detection, but where its coarse-grained entropy production is shown to contain a new contribution compared to the isolated SET. This additional contribution can be identified as the information flow generated by the ``Maxwell demon'' feedback in an idealized limit.

We study multicellular tumor spheroids by introducing a new three-dimensional agent-based Voronoi-Delaunay hybrid model. In this model, the cell shape varies from spherical in thin solution to convex polyhedral in dense tissues. The next neighbors of the cells are provided by a weighted Delaunay triangulation with on average linear computational complexity. The cellular interactions include direct elastic forces and cell-cell as well as cell-matrix adhesion. The spatiotemporal distribution of two nutrients—oxygen and glucose—is described by reaction-diffusion equations. Viable cells consume the nutrients, which are converted into biomass by increasing the cell size during the ${\mathrm{G}}_1$ phase. We test hypotheses on the functional dependence of the uptake rates and use computer simulations to find suitable mechanisms for the induction of necrosis. This is done by comparing the outcome with experimental growth curves, where the best fit leads to an unexpected ratio of oxygen and glucose uptake rates. The model relies on physical quantities and can easily be generalized towards tissues involving different cell types. In addition, it provides many features that can be directly compared with the experiment.

We compare different quantum master equations for the time evolution of the reduced density matrix. The widely applied secular approximation (rotating wave approximation) applied in combination with the Born-Markov approximation generates a Lindblad-type master equation ensuring for completely positive and stable evolution and is typically well applicable for optical baths. For phonon baths however, the secular approximation is expected to be invalid. The usual Markovian master equation does not generally preserve positivity of the density matrix. As a solution we propose a coarse-graining approach with a dynamically adapted coarse-graining time scale. For some simple examples we demonstrate that this preserves the accuracy of the integro-differential Born equation. For large times we analytically show that the secular approximation master equation is recovered. The method can in principle be extended to systems with a dynamically changing system Hamiltonian, which is of special interest for adiabatic quantum computation. We give some numerical examples for the spin-boson model of cases where a spin system thermalizes rapidly, and other examples where thermalization is not reached.

We calculate the radiation resulting from the Unruh effect for strongly accelerated electrons and show that the photons are created in pairs whose polarizations are perfectly correlated. Apart from the photon statistics, this quantum radiation can further be discriminated from the classical (Larmor) radiation via the different spectral and angular distributions. The signatures of the Unruh effect become significant if the external electromagnetic field accelerating the electrons is not too far below the Schwinger limit and might be observable with future facilities. Finally, the corrections due to the birefringent nature of the QED vacuum at such ultrahigh fields are discussed.