Christian David Weber

Dr. Christian David Weber

Department of Orthopaedics, Trauma and Reconstructive Surgery, RWTH Aachen University, Pauwelsstr. 30, 52074 Aachen, Germany
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Research Focus & Metrics

Academic Career Length

15Years (2012-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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9 October 2023 in Knee Surgery, Sports Traumatology, Arthroscopy
Verified
Journal Article
Open access
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Filippo MiglioriniFilippo Migliorini
Filippo Migliorini
LSLuise Schäfer
Luise Schäfer
ABAndreas Bell
Andreas Bell
Christian David WeberChristian David Weber
Christian David Weber
GVGianluca Vecchio
Gianluca Vecchio
Nicola MaffulliNicola Maffulli
Nicola Maffulli
Purpose: Meniscal tears are common and may impair knee function and biomechanics. This meta‐analysis compared meniscal repair versus resection in patients with symptomatic meniscal tears in terms of patient‐reported outcomes measures (PROMs), joint width, surgical failure, and rate of progression to osteoarthritis (OA) at conventional radiography.Methods: This study was conducted according to the 2020 PRISMA statement. In August 2023, the following databases were accessed: PubMed, Web of Science, Google Scholar, and Embase. Two reviewers independently performed the analysis and a methodological quality assessment of the included studies. All the clinical investigations which compared repair versus resection of meniscal tears were accessed.Results: Data from 20 studies (31,783 patients) were collected. The mean BMI was 28.28 ± 3.2 kg/m2, and the mean age was 37.6 ± 14.0 years. The mean time elapsed from injury to surgery was 12.1 ± 10.2 months and the mean medial joint width was 4.9 ± 0.8 mm. Between studies comparability at baseline was found in age, women, BMI, time from injury to surgery and length of the follow‐up, PROMs, medial joint width, and stage of OA. The resection group demonstrated a greater Lysholm score (P = 0.02). No difference was found in the International Knee Documentation Committee (P = 0.2). Nine studies reported data on the rate of failures at a mean of 63.00 ± 24.7 months. No difference was found between the two groups in terms of persistent meniscal symptoms (P = 0.8). Six studies reported data on the rate of progression to total knee arthroplasty at a mean of 48.0 ± 14.7 months follow‐up. The repair group evidenced a lower rate of progression to knee arthroplasty (P = 0.0001). Six studies reported data on the rate of advanced knee OA at a mean of 48.0 ± 14.7 months of follow‐up. The repair group evidenced a lower rate of advanced knee OA (P = 0.0001). No difference was found in the mean joint space width (P = 0.09).Conclusion: Meniscal repair is associated with a lower progression to knee osteoarthritis at approximately six years of follow‐up compared to partial meniscectomy. No difference in PROMs, medial joint width, and failures were evidenced.Level of evidence: Level III, meta‐analysis.

21 December 2017 in World Journal of Surgery
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Christian David WeberChristian David Weber
Christian David Weber
RLRolf Lefering
Rolf Lefering
PKPhilipp Kobbe
Philipp Kobbe
KHKlemens Horst
Klemens Horst
MPMiguel Pishnamaz
Miguel Pishnamaz
TDTraumaRegister DGU
TraumaRegister DGU

2 February 2018 in European Journal of Trauma and Emergency Surgery
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Journal Article
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Christian David WeberChristian David Weber
Christian David Weber
FHFrank Hildebrand
Frank Hildebrand
PKPhilipp Kobbe
Philipp Kobbe
RLRolf Lefering
Rolf Lefering
RSRichard M. Sellei
Richard M. Sellei
TDTraumaRegister DGU
TraumaRegister DGU

10 November 2015 in European Journal of Trauma and Emergency Surgery
Verified
Journal Article
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Christian David WeberChristian David Weber
Christian David Weber
TDTraumaRegister DGU
TraumaRegister DGU
KHK. Horst
K. Horst
RLR. Lefering
R. Lefering
MHM. Hofman
M. Hofman
HPH.-C. Pape
H.-C. Pape

29 October 2022 in Life
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Journal Article
Open access
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Filippo MiglioriniFilippo Migliorini
Filippo Migliorini
Nicola MaffulliNicola Maffulli
Nicola Maffulli
ABAndreas Bell
Andreas Bell
FHFrank Hildebrand
Frank Hildebrand
Christian David WeberChristian David Weber
Christian David Weber
PLPhilipp Lichte
Philipp Lichte
Autologous matrix-induced chondrogenesis (AMIC) has been advocated for the management of talar osteochondral lesions (OCLs). This systematic review, which was conducted according to the PRISMA 2020 guidelines, investigated the clinical and imaging efficacy and safety of the AMIC technique in the management of OCLs of the talus. Only studies investigating AMIC for talar chondral defects that were published in peer-reviewed journals were considered. In September 2022, the following databases were accessed: PubMed, Web of Science, Google Scholar, and Embase. Data on the visual analogue scale (VAS), American Orthopaedic Foot and Ankle Score (AOFAS), Tegner activity scale, and Foot Function Index (FFI) were retrieved. To evaluate the morphological MRI findings, data obtained from the magnetic resonance observation of cartilage repair tissue (MOCART) scores were evaluated. Data on hypertrophy, failures, and revision surgeries were also collected. Data from 778 patients (39% women, 61% men) were collected. The mean length of the follow-up was 37.4 ± 16.1 months. The mean age of the patients was 36.4 ± 5.1 years, and the mean BMI was 26.1 ± 1.6 kg/m2. The mean defect size was 2.1 ± 1.9 cm2. Following the AMIC technique, patients demonstrated an improved VAS (p < 0.001), AOFAS (p < 0.001), and FFI (p = 0.02) score. The MOCART score also improved from the baseline (p = 0.03). No difference was observed in the Tegner score (p = 0.08). No graft delamination and hypertrophy were reported in 353 patients. 7.8% (44 of 564) of patients required revision surgeries, and 6.2% (32 of 515) of patients were considered failures. The AMIC technique could be effective in improving symptoms and the function of chondral defects of the talus.

10 January 2020 in European Journal of Trauma and Emergency Surgery
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CCCassian Cremerius
Cassian Cremerius
GGGertraud Gradl-Dietsch
Gertraud Gradl-Dietsch
FBFrank J.P. Beeres
Frank J.P. Beeres
BLBjörn-Christian Link
Björn-Christian Link
LHLea Hitpass
Lea Hitpass
Matthias KnobeMatthias Knobe
Matthias Knobe