Many web-based pharmaceutical e-commerce platforms allow consumers to post open-ended textual reviews based on their purchase experiences. Understanding the true voice of consumers by analyzing such a large amount of user-generated content is of great significance to pharmaceutical manufacturers and e-commerce websites. The aim of this paper is to automatically extract hidden topics from web-based drug reviews using the structural topic model (STM) to examine consumers’ concerns when they buy drugs online. The STM is a probabilistic extension of Latent Dirichlet Allocation (LDA), which allows the consolidation of document-level covariates. This innovation allows us to capture consumer dissatisfaction along with their dynamics over time. We extract 12 topics, and five of them are negative topics representing consumer dissatisfaction, whose appearances in the negative reviews are substantially higher than those in the positive reviews. We also come to the conclusion that the prevalence of these five negative topics has not decreased over time. Furthermore, our results reveal that the prevalence of price-related topics has decreased significantly in positive reviews, which indicates that low-price strategies are becoming less attractive to customers. To the best of our knowledge, our work is the first study using STM to analyze the unstructured textual data of drug reviews, which enhances the understanding of the aspects of drug consumer concerns and contributes to the research of pharmaceutical e-commerce literature.

Given the unwieldy glut of information in online health question-answer (Q&A) service, it is essential to understand what constitutes helpful answers in the medical domain. Despite the fact that studies have examined the impacts of answer content factors on answer helpfulness, there are two gaps that need further analysis. First, the empirical results of the existing relevant studies on the effect of answer emotion are inconsistent. Second, prior studies only have examined the independent impacts of answer content factors and question content cues on answer helpfulness. To fill this gap, a research model reflecting the impacts of emotional content and question-answer congruence on answer helpfulness was developed and empirically examined. Our empirical analyses confirm that emotional content and answer helpfulness are related to one another in the form of an inverted U-shape and indicate that two types of question-answer congruence (emotional intensity congruence and linguistic style matching) positively affect answer helpfulness. Theoretical and practical implications are discussed.

Bacillus licheniformis HDYM-04 was isolated in flax retting water and showed β-mannanase activity. Carbon sources for β-mannanase production, as well as the fermentation conditions and feeding strategy, were optimized in shake flasks. When glucose or konjac powder was used as the carbon source, the β-mannanase activity was 288.13 ± 21.59 U/mL and 696.35 ± 23.47 U/mL at 24 h, respectively, which was approximately 4.4- to 10.68-fold higher than the values obtained with wheat powder. When 0.5% (w/v) glucose and 1% (w/v) konjac powder were added together, maximum enzyme activities of 789.07 ± 25.82 U/mL were obtained, an increase of 13.35% compared to the unoptimized cultures with only 1% (w/v) konjac powder. The enzyme activity decreased in the presence of 1% (w/v) konjac powder, but the highest enzyme activity was 1,533.26 ± 33.74 U/mL, a 1.2-fold increase compared with that in nonoptimized cultures; when 0.5% (w/v) glucose was used, the highest enzyme activity was 966.53 ± 27.84 U/mL, an increase in β-mannanase activity of 38.79% compared with control cultures. In this study, by optimizing fed-batch fermentation conditions, the yield of β-mannanase produced by HDYM-04 was increased, laying the foundation for the industrial application and further research of B. licheniformis HDYM-04.

Live streaming commerce, integrating real-time interaction with online retailing, is reshaping consumer behavior. While prior studies have focused on sales drivers, how to attract viewers remains underexplored. This study fills this gap by analyzing how short videos drive traffic acquisition in live streaming commerce, using a large Douyin dataset and OLS regressions with multiple robustness checks. Results show that sociability (likes, comments) and demographic match between streamers and viewers (gender, geography) enhance traffic acquisition, whereas commercialization through sponsored ads weakens it. The interval between video release and live streaming shows an inverted U-shaped effect on traffic acquisition. Moreover, streamer influence dampens the positive effects of sociability and matching, while production input mitigates the negative impact of commercialization. This study advances research on short video marketing and live streaming commerce and offers guidance for global digital commerce participants to optimize short video strategies for greater engagement and value.