Современные технологии и уровень фундаментальных исследований позволяют создавать медицинские сорбенты с заранее определенными структурными, прочностными и адсорбционными свойствами. Сорбционные материалы интересны не только в роли детоксикантов, используемых для удаления токсических агентов из жидких сред, но и в качестве носителей для доставки в зоны терапевтического воздействия биологически активных веществ. Целью работы является обоснование состава полифункционального препарата с антибактериальным и детоксикационным эффектами за счет комплекса серебра и сорбционной составляющей – алюмо-кремний содержащего сорбента. Материалы и методы. В работе использовали физико-химические (сорбционная активность красителя метиленового синего, удельная поверхность, водородный показатель при контакте с водой, атомноэмиссионная спектрометрия с индуктивно-связанной плазмой) и фармацевтические методы (насыпная плотность, растворение для твердых дозированных лекарственных форм исследования). Результаты и обсуждение. Обоснован двухстадийный способ иммобилизации комплекса серебра и гидрофобизатора на поверхность сорбционной матрицы. Выделен образец оптимального состава серебросодержащего препарата: оксид – гидроксид алюминия – 99,2%, кластерное серебро (Арговит – С 2%) – 0,3% в расчете на серебро и вспомогательное вещество (гидрофобизатор – ПМС марка П – 841) – 0,5%. Выход серебра в раствор из образца указанного состава за 8 часов не превышал 1,6 ± 0,3%, величина удельной поверхности – 90 м2/г, величина водородного показателя – 8,1 ± 0,02, насыпная плотность – 1,12 ± 0,11 г/см3. Заключение. В работе экспериментально обоснован состав серебросодержащего препарата AlSi/Ag, получены комплексные научные данные о его физико-химических, технологических особенностях.

We have done EEG tests on athletes and in unfit subjects aged between 18 and 23 in order to study endurance and changes in bioelectrical activity of the brain caused by local forearm muscular...

Introduction. The article examines biosocial correction of the psycho-emotional status and behavior of individuals with high levels of neuropsychological stress. The purpose of the article is to reveal the psychophysiological criteria of human functional states, to summarize the data from scholarly literature and experimental research, and to propose and substantiate the psychophysiological correction method to ensure biosocial safety. Materials and Methods. The theoretical and methodological basis of the study was the psychophysiological approach and its basic principles. Psychophysiological examinations included electroencephalography, computer testing of psychomotor reactions of varying complexity (D. A. Morocco), self-assessment of activity, well-being and mood indicators (Doskin’s inventory), Spielberger’s State-Trait Anxiety Inventory, as well as indicators of heart rate structure variability (R. M. Bayevsky). The research sample consisted of undergraduates and postgraduates aged between 18 and 28 years (n = 37, 24 ± 3 years). The participants were distributed into two groups. The first group comprised individuals regularly engaged in psychophysical self–regulation; the second group consisted of people who were not engaged in psychophysical self–regulation . Statistical processing of the obtained results was conducted using a computer package of application programs Statistica 10.0 and SPSS. Results. The article provides a theoretical overview and experimental data on the problem of biosocial causes of inadequate reactions of individuals with a high level of neuropsychological stress. The possibilities of biosocial correction of psycho-emotional status and human behavior are shown. The study has revealed the improvements in functional state of optimal adaptation after regular classes on the theory and practice of self-regulation techniques, including relaxation. The authors summarized current indicators of psychophysiological status and demonstrated the effectiveness of remedial training in restoring the optimal neuropsychological status required for an individual's biosocial safety. Conclusions. The article concludes that in order to ensure the biosocial security of an individual, it is necessary to teach methods of psychophysical self-regulation in order to normalize the psychophysical state, reduce the level of neuropsychological stress, and, consequently, the risks of non-adaptive behavior, which is particularly important for young adults.

In this paper a holonomic system in the homogeneous gravity field on a vertically vibrating base is considered. It is shown that all the equilibrium positions that the system has without vibrations persist as frequency of vibration tends to infinity. The stability conditions of the equilibrium positions of the limit system are obtained. Similar conclusions are valid for the steady motions.

Aim. The article aims to assess the psychophysiological characteristics of skilled athletes in combat sports (boxing, freestyle wrestling, judo). Materials and methods. 18–23-year-old skilled combat athletes were examined. All athletes were divided into the following groups: the first group - female athletes (n = 15); the second group - male athletes (n = 17); the third and fourth groups - control groups consisted of males and females of the same age and not involved in sports (15 people each). The following methods were used: a pulse measurement, psychological tests, self-assessment of the psychoemotional status, electroencephalography, cardiointervalography with the calculation of statistical indicators of heart rate. Examinations were performed before and after the relaxation exercise, which was a three-minute concentration of attention at a specific point on the body. Results. The results revealed that female athletes had lower indicators of psychoemotional status than males but higher than untrained females. The indicators of psychoemotional stress were lower in female athletes than in male athletes and untrained women. For example, the indicator of personal anxiety in female athletes was 41.0 ± 1.8 versus 47.2 ± 2.5 in untrained women (P < 0.05). In female athletes, heart rate, the amplitude of the mode and voltage index (77.15 ± 2.05) in the structure of heart rate were slightly higher than in males (73.10 ± ± 1.07), which indicated greater functional stress of the heart. Relaxation led to favorable changes in EEG indicators and decreased functional stress of the heart in all subjects. Conclusion. It is recommended to extend the terms of sports training in female combat athletes to ensure a smooth transition to sports specialization and reduce injuries.