Silvio Danese is a Gastroenterologist and Professor of Gastroenterology at Vita-Salute San Raffaele University and IRCCS San Raffaele Hospital, Milan, Italy. Since October 2021, he has been Head of the Gastroenterology and Gastrointestinal Endoscopy Unit. Before that, he was Head of the IBD Centre and ImmunoCentre at IRCCS Humanitas, Rozzano, Milan, Italy, and Professor of Gastroenterology at Humanitas University. He was trained in Gastroenterology at Policlinico Gemelli, Rome, and graduated as a PhD, working from 2001 to 2004 in Dr. Claudio Fiocchi’s laboratory at the Case Western Reserve University, Cleveland, Ohio, USA. His main research area of interest is the investigation of the fundamental mechanisms underlying IBD pathogenesis, while his daily clinical activity is related to IBD service. He is actively involved in many international clinical trials in IBD. He is a member of many organizations related to the IBD field, including the European Crohn’s and Colitis Organization (ECCO), where he was the past president (2018–2020).