ABO3-based photocatalysts for water splitting were systematically reviewed in this manuscript. Crystal structure and chemical composition characteristics of ABO3 materials were briefly introduced to guide the modification of ABO3-based photocatalysts. The ABO3-based photocatalysts were then reviewed in detail and divided into four groups based on the employed modification strategies, i.e., chemical component adjustment, micro-/nano-structure adjustment, local lattice structure adjustment, and application of the modification strategy of ABO3 photocatalysts in designing AxByOz photocatalysts. In this section, the recent research works on ABO3-based photocatalysts in our group were presented. Finally, application of ABO3 photocatalysts in Z-scheme systems for overall water splitting was introduced. This review summarized the development of ABO3-based photocatalysts and showed the values and possible direction of future research, thereby offering a guide for photocatalytic water splitting