Jan Krakowiak

Prof. Jan Krakowiak

orcid

Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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WKWojciech Konarski
Wojciech Konarski
TPTomasz Poboży
Tomasz Poboży
Andrzej ŚliwczyńskiAndrzej Śliwczyński
Andrzej Śliwczyński
IKIreneusz Kotela
Ireneusz Kotela
JKJan Krakowiak
Jan Krakowiak
AKAndrzej Kotela
Andrzej Kotela
Avascular necrosis (AVN) of the femoral head is caused by disruption of the blood supply to the proximal femur. The alterations in the blood supply may occur following a traumatic event or result from a non-traumatic cause. Femoral neck fracture and hip dislocation and associated surgical procedures, corticosteroid therapy, and alcohol abuse frequently lead to AVN development. Type of fracture (displaced or undisplaced) and time between injury and surgery are the most critical factors in assessing the risk of developing AVN. Diagnosis of AVN can be established based on patients’ complaints, medical history, and radiographic findings. There is no consensus on the treatment of patients with AVN to date. Non-surgical methods are dedicated to patients in the early pre-collapse stages of the disease and consist of pharmacotherapy and physiotherapy. Surgery is recommended for patients with advanced disease.

16 July 2022 in Medicina
Verified
Journal Article
Open access
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PDPaweł Dybciak
Paweł Dybciak
EHEwa Humeniuk
Ewa Humeniuk
Dorota RaczkiewiczDorota Raczkiewicz
Dorota Raczkiewicz
JKJan Krakowiak
Jan Krakowiak
Artur WdowiakArtur Wdowiak
Artur Wdowiak
IBIwona Bojar
Iwona Bojar
Background and Objectives: Mental health disorders are often the consequence of hormonal disorders such as those accompanying polycystic ovary syndrome (PCOS), where changes in appearance and having to deal with a number of other problems occur due to this illness. The objective of this study was to determine the prevalence and severity of anxiety and depression symptoms, the level of ego-resiliency, and the ways that women with PCOS cope with stress compared to healthy women in order to determine the influence of socio-demographic characteristics in relation to levels of anxiety and depression with ego-resiliency and stress-coping methods. Materials and Methods: The study was conducted in Poland in 2021 and included 230 women with PCOS and 199 healthy controls aged 20–40 years old. The hospital anxiety and depression scale (HADs), ego-resiliency scale, as well as the MINI-COPE inventory were used. Results: The women with PCOS had higher levels of anxiety and depression and poorer ego-resiliency in comparison to the healthy women. The women with PCOS used passive stress-coping strategies significantly more commonly than the healthy women. Living in rural areas, having a lower level of education and being childless increased anxiety levels. Similarly, being over 30, living in a rural area, having a lower level of education, being childless, and being obese increased depression levels in the women with PCOS. A low level of ego-resiliency and passive stress-coping strategies are predictors of high levels of anxiety and depression in women with PCOS. Conclusions: Women with PCOS should be checked for anxiety and depression. They should also be checked to see whether they have the resources to cope with chronic stress in order to optimize therapeutic interventions.

26 June 2023 in Healthcare
Verified
Journal Article
Open access
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WKWojciech Konarski
Wojciech Konarski
TPTomasz Poboży
Tomasz Poboży
KKKlaudia Konarska
Klaudia Konarska
Andrzej ŚliwczyńskiAndrzej Śliwczyński
Andrzej Śliwczyński
IKIreneusz Kotela
Ireneusz Kotela
JKJan Krakowiak
Jan Krakowiak
Osteonecrosis (ON) is usually a progressive disease that negatively affects the quality of life and leads to significant disability. Most patients are aged 30–50 years and require multiple surgical interventions throughout their lifetime. In non-traumatic ON, alcohol abuse and corticosteroids are involved in up to 80% of cases. This narrative review aims to summarize data on their impact on healthy bone and the development of pathophysiological processes leading to ON development. We conducted EMBASE and MEDLINE database reviews to identify relevant research. We found that for both agents, the risk was time and dose-dependent. ON in alcohol and steroid use shared many pathogenetic mechanisms leading to the development of necrosis, including increased adipogenesis, the induction of chronic inflammation, vascular alterations, and impaired bone-cell differentiation. Because both alcohol and steroid use are modifiable factors, both general physicians and orthopedic surgeons should encourage patients to limit ethanol intake and avoid corticosteroid overuse. In the presence of ON, because both alcohol- and steroid-induced disease tend to be multifocal, addiction treatment and limiting steroid use are justified.

WKWojciech Konarski
Wojciech Konarski
TPTomasz Poboży
Tomasz Poboży
AKAndrzej Kotela
Andrzej Kotela
Andrzej ŚliwczyńskiAndrzej Śliwczyński
Andrzej Śliwczyński
IKIreneusz Kotela
Ireneusz Kotela
JKJan Krakowiak
Jan Krakowiak
Background: Avascular necrosis (AVN) of the femoral head often requires surgical treatment and is often associated with femoral neck fractures. We conducted a systematic review and meta-analysis of recent research on the risk of AVN following the stabilization of fractured femoral neck with implants in PubMed. We assessed the effect of age on AVN incidence among patients aged > 50 and younger, depending on fracture type, Garden stage, Pouwels degree, Delbet stage, and age category. We followed PRISMA guidelines. Relevant studies were defined as research articles describing real-world studies reporting on the risk of AVN following primary surgical fracture stabilization with implants, published between 1 January 2011 and 22 April 2021. Fifty-two papers met the inclusion criteria, with a total of N = 5930 with surgically managed fractures. The pooled mean AVN incidence was significantly higher among patients with displaced fractures (20.7%; 95% CI: 12.8–28.5%) vs. those with undisplaced fractures (4.7%; 95% CI: 3.4–6.0%). No significant correlation was observed between AVN incidence weighted by sample size and time interval from injury to surgery (p = 0.843, R2 = 0.01). In conclusion, the risk of AVN following femoral neck fractures was generally high, especially in patients with displaced fractures. The time from injury to surgery did not correlate with AVN incidence.

WKWojciech Konarski
Wojciech Konarski
TPTomasz Poboży
Tomasz Poboży
AKAndrzej Kotela
Andrzej Kotela
Andrzej ŚliwczyńskiAndrzej Śliwczyński
Andrzej Śliwczyński
IKIreneusz Kotela
Ireneusz Kotela
JKJan Krakowiak
Jan Krakowiak
Avascular osteonecrosis (AVN) is caused by the disrupted blood supply to the bone. Most AVN cases occur in the femoral head, but other sites might be affected as well, including the jaw or distal bones of the extremities. Previous studies suggested that diabetes could increase the risk of AVN of the jaw, but the relationship between diabetes and AVN in other bone sites is unclear. This systematic review and meta-analysis aimed to summarize the evidence from studies that had reported on the occurrence of AVN in sites other than the jaw, depending on the diagnosis of diabetes. Overall, we included 6 observational studies carried out in different populations: primary or secondary AVN of the femoral head, Takayasu arteritis, general population, kidney transplant recipients, systemic lupus erythematosus, and primary brain tumors. A random-effects meta-analysis showed that the risk of AVN in sites other than the jaw was non-significantly increased in patients with diabetes (odds ratio: 1.90, 95% confidence interval: 0.93–3.91). The pooled estimate increased and was significant after the exclusion of one study (2.46, 1.14–5.32). There was a significant heterogeneity (I2 = 65%, tau2 = 0.48, p = 0.01; prediction interval, 0.21–16.84). There was no significant publication bias (p = 0.432). In conclusion, diabetes could increase the risk of AVN in sites other than the jaw, but the available evidence is limited. There is a need for large, well-designed, population-based studies.

22 March 2019 in Annals of Agricultural and Environmental Medicine
Verified
Journal Article
Open access
KSKatarzyna Sygit
Katarzyna Sygit
MSMarian Sygit
Marian Sygit
PWPaulina Wojtyła-Buciora
Paulina Wojtyła-Buciora
OLOleg Lubiniec
Oleg Lubiniec
WSWłodzimierz Stelmach
Włodzimierz Stelmach
JKJan Krakowiak
Jan Krakowiak
Introduction. Physical activity is one of the basic needs of people throughout their lives. Physical activity prevents many diseases, including cardiovascular diseases, which have the highest mortality rate, both among urban and rural populations in Poland. The average life expectancy in Poland and the European Union is increasing. The proportion of children and adolescents under the age of 20 is decreasing slowly but steadily, while the proportion of older people (aged 65+) in the total population is gradually increasing. According to the forecast of the Central Statistical Office, the percentage of older people increased rapidly after 2010, and will reach 22.3% in 2030. The number of the elderly will increase from 5,134,000 in 2007 to 8,195,000 in 2030. The health situation of Poles is less favourable compared to other European Union states. The most common health risks are: nicotine, drug addiction, alcoholism and obesity. One of the causes of obesity is an unhealthy lifestyle. Lifestyle is a basic determinant of human health. Objective. The aim of this study is to present research results based on a literature review on the importance of physical activity for human health as an element of organizing and managing the lifestyle of urban and rural populations. Conclusions. Comprehensive measures should be taken to increase public health awareness and promote health education, especially among school-age children and youths, and to provide appropriate sports infrastructure in particularly neglected rural areas.