Guohua Wang

Guohua Wang


Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 July 2019 in Quantitative Imaging in Medicine and Surgery
Verified
Journal Article
Closed access
YLYanxia Liu
Yanxia Liu
HSHongyu Shi
Hongyu Shi
SHSijuan Huang
Sijuan Huang
XCXiaochuan Chen
Xiaochuan Chen
HZHuimin Zhou
Huimin Zhou
XYXin YANG
Xin YANG
Acute xerostomia is the most common side effect of radiation therapy (RT) for head and neck (H&N) malignancies. Investigating radiation-induced changes of computed tomography (CT) radiomics in parotid glands (PGs) and saliva amount (SA) can predict acute xerostomia during the RT for nasopharyngeal cancer (NPC). CT and SA data from 35 patients with stages I-IVB were randomly collected from an NPC clinical trial registered on the clinicaltrials.gov (ID: NCT01762514). All patients received radical treatment based on intensity-modulated RT (IMRT) with a prescription dose of 68.1 Gy in 30 fractions. The patients' ages ranged 24-72 years, and each patient had five CT sets acquired at treatment position: at the 0th, 10th, 20th, 30th fractions during the RT, and at 3-month later after the RT. The PGs for each CT set were delineated by a radiation oncologist and verified independently by another. Patients' saliva was collected every other 10 days during the RT. Acute xerostomia was evaluated based on the RTOG acute toxicity scoring and the SA. In total, 1,703 radiomics features were calculated for PGs from each CT set, including feature value at 0th fraction (FV0F), FV10F, and delta FV (ΔFV10F-0F), respectively. Extensive experiments were conducted to achieve the optimal results. RidgeCV and Recursive Feature Elimination (RFE) were used for feature selection, while linear regression was used for predicting SA30F. Four more patients were added for independent testing. Substantial changes in various radiomics metrics of PGs were observed during the RT. Eight normalized feature value (NFV), selected from NFV0F, predicted SA10F with a mean square error (MSE) of 0.9042 and a R2 score of 0.7406. Fourteen NFV, selected from ΔNFV10F-0F, NFV0F, and NFV10F to predict SA30F, showed the best predictive ability with an MSE of 0.0569. The model predicted the level of acute xerostomia with a precision of 0.9220 and a sensitivity of 100%, compared to the clinical observed SA. For the independent test, the MSE of PSA30F was 0.0233. This study demonstrated that radiation-induced acute xerostomia level could be early predicted based on the SA and radiomics changes of the PGs during IMRT delivery. SA, NFV0F, NFV10F, and especially ΔNFV10F-0F provided the best performance on acute xerostomia prediction for individual patient based on RidgeCV_RFE_LinearRegression method of delta radiomics.

JHJie Hua
Jie Hua
GWGuohua Wang
Guohua Wang
MHMao Lin Huang
Mao Lin Huang
SHShuyang Hua
Shuyang Hua
SYShuanghe Yang
Shuanghe Yang
Virus outbreaks are threats to humanity, and coronaviruses are the latest of many epidemics in the last few decades in the world. SARS-CoV (Severe Acute Respiratory Syndrome Associated Coronavirus) is a member of the coronavirus family, so its study is useful for relevant virus data research. In this work, we conduct a proposed approach that is non-medical/clinical, generate graphs from five features of the SARS outbreak data in five countries and regions, and offer insights from a visual analysis perspective. The results show that prevention measures such as quarantine are the most common control policies used, and areas with strict measures did have fewer peak period days; for instance, Hong Kong handled the outbreak better than other areas. Data conflict issues found with this approach are discussed as well. Visual analysis is also proved to be a useful technique to present the SARS outbreak data at this stage; furthermore, we are proceeding to apply a similar methodology with more features to future COVID-19 research from a visual analysis perfective.

4 July 2023 in IEEE Transactions on Affective Computing
Verified
Journal Article
Closed access
YZYushi Zeng
Yushi Zeng
GWGuohua Wang
Guohua Wang
HRHaopeng Ren
Haopeng Ren
YCYi Cai
Yi Cai
HLHo-Fung Leung
Ho-Fung Leung
QHQingbao Huang
Qingbao Huang
Cross-domain aspect-based sentiment analysis has recently attracted significant attention, which can effectively alleviate the problem of lacking large-scale labeled data for supervised learning based methods. Most of current methods mainly focus on extracting domain-shared syntactic features to conduct the domain adaptation. Due to the language and syntax are diverse between domains, these methods lack generalization and even lead to syntactic transfer errors. External knowledge graphs have rich domain commonsense and share the relational structures between source and target domains. The domain-shared relational structure can effectively bridge the gap across domains and solve the problem of syntactic transfer errors. Moreover, not all the introduced external knowledge is equally important for the cross-domain aspect-based sentiment analysis. Motivated by these, we propose a knowledge-enhanced and topic-guided cross domain aspect-based sentiment analysis model with the domain-shared commonsense relational structure learning module and the topic-guided knowledge attention module. Extensive experiments are conducted and the experimental results evaluate the effectiveness of our proposed model.

1 January 2018 in Filomat
Verified
Journal Article
Open access
PDF file
JHJie Hua
Jie Hua
MHMao Lin Huang
Mao Lin Huang
GWGuohua Wang
Guohua Wang
MZMouataz Zreika
Mouataz Zreika
Decision making in stock investment is often made based on current events in the market and the analysis of historical data on specific stocks. Besides, similar rates of price changing over a longterm period on different stocks may indicate potential connections between those listed corporations. The proposed methodology applies the force-directed algorithm and time-series chart to offer stakeholders capability to gain deeper insights initiative on potential relationships between stocks comes with less human interventions. Hence to assist in future decision making on stock investment via graph layouts.

31 January 2024 in IEEE Transactions on Multimedia
Verified
Journal Article
Closed access
JLJianwei Lu
Jianwei Lu
GWGuohua Wang
Guohua Wang
YCYi Cai
Yi Cai
XWXin Wu
Xin Wu
Infographics, which usually contain many well-designed visual elements, have significant advantages in delivering information efficiently and accurately. Previous research shows that proportion-related infographics make up the majority of all infographics. However, the creation of proportion-related infographics is difficult for general users. Recently, many researchers focus on generating infographics from the text with a single proportional fact. Our further research found that users tend to create infographics with multiple proportional facts. Existing research lacks modeling of relations between different facts, resulting in poor performance when generating infographics with multiple facts. In this paper, we model the relationship of different proportional facts based on the results of our investigation and design a deep learning-based model to classify them. At the same time, we also optimize the ability to extract multiple proportional facts from text. The experiments show that our model outperforms existing models when visualizing text with multiple proportional facts.