Accumulating evidence has shown that lncRNA GAS5 is a novel tumour-promoting RNA that contributes to tumour progression by sponging miRNAs. However, the detailed role of lncRNA GAS5 in B lymphocytic leukaemia is still unclear. A qRT-PCR assay was use

This paper provides some existence results about first-order fuzzy differential equation with two-point boundary value condition. Firstly, we study a class of linear fuzzy differential equation and some necessary conditions for the existence of solutions are provided. Based on these conditions and the upper and lower solutions method, we obtain some existence results about first-order nonlinear differential equations with the same boundary value condition.

As an important aspect of the educational service, school bus plays a significant role in student's daily travel. School bus routing problem is an important part of school bus transport system. Rational optimization of the school bus routing operation can reduce the cost of school bus service and bring convenience to students and their families, so it has theoretical and practical significance. This paper studies the related model and algorithm of school bus routing problem. For single-center and single-vehicle problem, mathematical model is built. As a case, a secondary school in Beijing is selected and analyzed intensively. The strategy of location-allocation-routing is used to complete the questionnaire analysis, address distribution analysis, stops selection and route generation. Then the problem is solved by ant colony optimization algorithm. The results show that the model proposed in this paper is applicable to real life.