The chemistry of cyclic imines has been gaining importance in the last decade because of their broad spectrum of applications and biological importance. This review focuses on the synthesis and utilization of these compounds with an emphasis on strategic transformations in organic chemistry. Electron-deficient sulfamate-derived and N-sulfonyl cyclic imines are also discussed as examples of versatile synthons in organic synthesis.

New chiral tetrasubstituted aminophosphonic acid derivatives of hexahydroquinoxalin-2(1H)-one were synthesised via highly diastereoselective hydrophosphonylation of the corresponding imines with tris(trimethylsilyl) phosphite as phosphorus nucleophile. High asymmetric induction, good yields, mild reaction conditions, and ease of purification of the final products are the key advantages of the presented protocol.