Graziella Orru

Dr. Graziella Orru

Department of Surgical, Medical and Molecular & Critical Area Pathology, University of Pisa, Italy
orcid

Research Focus & Metrics

Academic Career Length

18Years (2009-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 April 2012 in Neuroscience & Biobehavioral Reviews
Verified
Journal Article
Closed access
Graziella OrruGraziella Orru
Graziella Orru
WPWilliam Pettersson-Yeo
William Pettersson-Yeo
AMAndre F. Marquand
Andre F. Marquand
GSGiuseppe Sartori
Giuseppe Sartori
AMAndrea Mechelli
Andrea Mechelli

31 July 2020 in Frontiers in Psychology
Verified
Journal Article
Open access
PDF file
CCCiro Conversano
Ciro Conversano
Rebecca CiacchiniRebecca Ciacchini
Rebecca Ciacchini
Graziella OrruGraziella Orru
Graziella Orru
MGMariagrazia Di Giuseppe
Mariagrazia Di Giuseppe
AGAngelo Gemignani
Angelo Gemignani
Andrea PoliAndrea Poli
Andrea Poli
Health care professionals (HCPs) are a population at risk for high levels of burnout and compassion fatigue. The aim of the present systematic review was to give an overview on recent literature about mindfulness and compassion characteristics of HCPs, while exploring the effectiveness of techniques, involving the two aspects, such as MBSR or mindfulness intervention and compassion fatigue-related programs. A search of databases, including PubMed and PsycINFO, was conducted following the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines and the methodological quality for this systematic review was appraised using AMSTAR-2 (A MeaSurement Tool to Assess systematic Reviews-2). The number of articles that met the inclusion criteria was 58 (4 RCTs, 24 studies with pre-post measurements, 12 cross-sectional studies, 11 cohort studies and 7 qualitative studies). MBSR intervention was effective at improving, and maintaining, mindfulness and self-compassion levels and to improve burnout, depression, anxiety, stress. The most frequently employed interventional strategies were mindfulness-related trainings that were effective at improving mindfulness and self-compassion, but not compassion fatigue, levels. Compassion-related interventions have been shown to improve self-compassion, mindfulness and interpersonal conflict levels. Mindfulness was effective at improving negative affect and compassion fatigue, while compassion satisfaction may be related to cultivation of positive affect. This systematic review summarized the evidence regarding mindfulness- and compassion-related qualities of HCPs as well as potential effects of MBSR, mindfulness-related and compassion-related interventions on professionals' psychological variables like mindfulness, self-compassion and quality of life. Combining structured mindfulness and compassion cultivation trainings may enhance the effects of interventions, limit the variability of intervention protocols and improve data comparability of future research.

24 May 2023 in Frontiers in Artificial Intelligence
Verified
Journal Article
Open access
Graziella OrruGraziella Orru
Graziella Orru
APAndrea Piarulli
Andrea Piarulli
CCCiro Conversano
Ciro Conversano
AGAngelo Gemignani
Angelo Gemignani
Backgrounds: The field of Artificial Intelligence (AI) has seen a major shift in recent years due to the development of new Machine Learning (ML) models such as Generative Pre-trained Transformer (GPT). GPT has achieved previously unheard-of levels of accuracy in most computerized language processing tasks and their chat-based variations.Aim: The aim of this study was to investigate the problem-solving abilities of ChatGPT using two sets of verbal insight problems, with a known performance level established by a sample of human participants.Materials and methods: A total of 30 problems labeled as “practice problems” and “transfer problems” were administered to ChatGPT. ChatGPT's answers received a score of “0” for each incorrectly answered problem and a score of “1” for each correct response. The highest possible score for both the practice and transfer problems was 15 out of 15. The solution rate for each problem (based on a sample of 20 subjects) was used to assess and compare the performance of ChatGPT with that of human subjects.Results: The study highlighted that ChatGPT can be trained in out-of-the-box thinking and demonstrated potential in solving verbal insight problems. The global performance of ChatGPT equalled the most probable outcome for the human sample in both practice problems and transfer problems as well as upon their combination. Additionally, ChatGPT answer combinations were among the 5% of most probable outcomes for the human sample both when considering practice problems and pooled problem sets. These findings demonstrate that ChatGPT performance on both set of problems was in line with the mean rate of success of human subjects, indicating that it performed reasonably well.Conclusions: The use of transformer architecture and self-attention in ChatGPT may have helped to prioritize inputs while predicting, contributing to its potential in verbal insight problem-solving. ChatGPT has shown potential in solving insight problems, thus highlighting the importance of incorporating AI into psychological research. However, it is acknowledged that there are still open challenges. Indeed, further research is required to fully understand AI's capabilities and limitations in verbal problem-solving.

Graziella OrruGraziella Orru
Graziella Orru
FMFrancesca Marzetti
Francesca Marzetti
CIRO CONVERSANOCIRO CONVERSANO
CIRO CONVERSANO
GVGuido Vagheggini
Guido Vagheggini
Mario MiccoliMario Miccoli
Mario Miccoli
AGAngelo Gemignani
Angelo Gemignani
(1) Background: The present study aims to assess the level of professional burnout and secondary traumatic stress (STS), and to identify potential risk or protective factors among health care workers (HCWs) during the coronavirus disease 2019 (COVID-19) outbreak.; (2) Methods: This cross-sectional study, based on an online survey, collected demographic data and mental distress outcomes from 184 HCWs from 1 May 2020, to 15 June 2020, from 45 different countries. The degree of STS, perceived stress and burnout was assessed using the Secondary Traumatic Stress Scale (STSS), the Perceived Stress Scale (PSS) and Maslach Burnout Inventory Human Service Survey (MBI-HSS) respectively. Stepwise multiple regression analysis was performed to identify potential risk and protective factors for STS; (3) Results: 184 HCWs (M = 90; Age mean: 46.45; SD: 11.02) completed the survey. A considerable proportion of HCWs had symptoms of STS (41.3%), emotional exhaustion (56.0%), and depersonalization (48.9%). The prevalence of STS was 47.5% in frontline HCWs while in HCWs working in other units it was 30.3% (p < 0.023); 67.1% for the HCWs exposed to patients’ death and 32.9% for those HCWs which were not exposed to the same condition (p < 0.001). In stepwise multiple regression analysis, perceived stress, emotional exhaustion, and exposure to patients’ death remained as significant predictors in the final model for STS (adjusted R2 = 0.537, p < 0.001); (4) Conclusions: During the current COVID-19 pandemic, HCWs facing patients’ physical pain, psychological suffering, and death are more likely to develop STS.

10 January 2020 in Frontiers in Psychology
Verified
Journal Article
Open access
PDF file
Graziella OrruGraziella Orru
Graziella Orru
MMMerylin Monaro
Merylin Monaro
CIRO CONVERSANOCIRO CONVERSANO
CIRO CONVERSANO
AGAngelo Gemignani
Angelo Gemignani
GSGiuseppe Sartori
Giuseppe Sartori
Recent controversies about the level of replicability of behavioral research analyzed using statistical inference have cast interest in developing more efficient techniques for analyzing the results of psychological experiments. Here we claim that complementing the analytical workflow of psychological experiments with Machine Learning-based analysis will both maximize accuracy and minimize replicability issues. As compared to statistical inference, ML analysis of experimental data is model agnostic and primarily focused on prediction rather than inference. We also highlight some potential pitfalls resulting from adoption of Machine Learning based experiment analysis. If not properly used it can lead to over-optimistic accuracy estimates similarly observed using statistical inference. Remedies to such pitfalls are also presented such and building model based on cross validation and the use of ensemble models. ML models are typically regarded as black boxes and we will discuss strategies aimed at rendering more transparent the predictions.

MGMariagrazia Di Giuseppe
Mariagrazia Di Giuseppe
GNGianni Nepa
Gianni Nepa
TPTracy A. Prout
Tracy A. Prout
FAFabrizio Albertini
Fabrizio Albertini
SMStefano Marcelli
Stefano Marcelli
CIRO CONVERSANOCIRO CONVERSANO
CIRO CONVERSANO
The experience of working on the frontlines of the COVID-19 healthcare crisis has presented a cumulative traumatic experience that affects healthcare professionals’ well-being. Psychological resources such as resilience and adaptive defense mechanisms are essential in protecting individuals from severe stress and burnout. During September 2020, 233 healthcare workers responded to an online survey to test the impact of demographic variables, COVID-19 exposure, and psychological resources in determining stress and burnout during the COVID-19 emergency. Frontline workers reported higher scores for stress, emotional exhaustion, and depersonalization (p < 0.001) as compared to colleagues working in units not directly serving patients with COVID-19. Mature defensive functioning was associated with resilience and personal accomplishment (r = 0.320; p < 0.001), while neurotic and immature defenses were related to perceived stress and burnout. Stress and burnout were predicted by lower age, female gender, greater exposure to COVID-19, lower resilience, and immature defensive functioning among healthcare professionals (R2 = 463; p < 0.001). Working on the frontlines of the COVID-19 pandemic appears to provoke greater stress and burnout. On the other hand, resilience and adaptive defense mechanisms predicted better adjustment. Future reaction plans should promote effective programs offering support for healthcare workers who provide direct care to patients with COVID-19.