Dr. Marc Muller
Université de Liège (ULiege)
'%3e%3cpath%20d='M22.1642%2019.0924C21.7317%2018.068%2021.1041%2017.1375%2020.3163%2016.3527C19.5309%2015.5656%2018.6006%2014.9381%2017.5766%2014.5048C17.5674%2014.5002%2017.5582%2014.4979%2017.5491%2014.4933C18.9774%2013.4616%2019.9059%2011.7811%2019.9059%209.88504C19.9059%206.74408%2017.3611%204.19922%2014.2201%204.19922C11.0792%204.19922%208.53429%206.74408%208.53429%209.88504C8.53429%2011.7811%209.46282%2013.4616%2010.8912%2014.4956C10.882%2014.5002%2010.8728%2014.5025%2010.8636%2014.5071C9.83652%2014.9404%208.91487%2015.5617%208.1239%2016.355C7.33685%2017.1404%206.70933%2018.0707%206.276%2019.0947C5.85031%2020.0972%205.62072%2021.172%205.59967%2022.2609C5.59905%2022.2853%205.60335%2022.3097%205.61229%2022.3325C5.62123%2022.3553%205.63465%2022.376%205.65174%2022.3935C5.66883%2022.4111%205.68926%2022.425%205.71182%2022.4345C5.73437%2022.444%205.7586%2022.4489%205.78308%2022.4489H7.15868C7.25956%2022.4489%207.3398%2022.3686%207.3421%2022.2701C7.38795%2020.5001%208.09868%2018.8425%209.35506%2017.5861C10.655%2016.2862%2012.3814%2015.5709%2014.2201%2015.5709C16.0588%2015.5709%2017.7852%2016.2862%2019.0852%2017.5861C20.3415%2018.8425%2021.0523%2020.5001%2021.0981%2022.2701C21.1004%2022.3709%2021.1807%2022.4489%2021.2815%2022.4489H22.6571C22.6816%2022.4489%2022.7058%2022.444%2022.7284%2022.4345C22.751%2022.425%2022.7714%2022.4111%2022.7885%2022.3935C22.8056%2022.376%2022.819%2022.3553%2022.8279%2022.3325C22.8369%2022.3097%2022.8412%2022.2853%2022.8406%2022.2609C22.8176%2021.165%2022.5907%2020.0989%2022.1642%2019.0924ZM14.2201%2013.8284C13.1678%2013.8284%2012.1773%2013.418%2011.4322%2012.6729C10.6871%2011.9278%2010.2767%2010.9374%2010.2767%209.88504C10.2767%208.83271%2010.6871%207.84227%2011.4322%207.09715C12.1773%206.35204%2013.1678%205.94165%2014.2201%205.94165C15.2724%205.94165%2016.2629%206.35204%2017.008%207.09715C17.7531%207.84227%2018.1635%208.83271%2018.1635%209.88504C18.1635%2010.9374%2017.7531%2011.9278%2017.008%2012.6729C16.2629%2013.418%2015.2724%2013.8284%2014.2201%2013.8284Z'%20fill='%238590A2'/%3e%3c/g%3e%3c/svg%3e)
Co-authors
Following
Followers
Research Focus & Metrics
Explore full metrics on Scilit
Academic Career Length
46Years (1981-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications24 February 2016 in Nature Materials
Journal Article
ABAslihan Babayigit
Aslihan Babayigit
AEAnitha Ethirajan
Anitha EthirajanMarc MullerBCBert Conings
Bert Conings
13 January 2016 in Scientific Reports
Journal Article
ABAslihan Babayigit
Aslihan Babayigit
Dinh Duy-ThanhAEAnitha Ethirajan
Anitha EthirajanJMJean Manca
Jean Manca
Marc MullerBCBert Conings
Bert Conings +1
Intensive development of organometal halide perovskite solar cells has lead to a dramatic surge in power conversion efficiency up to 20%. Unfortunately, the most efficient perovskite solar cells all contain lead (Pb), which is an unsettling flaw that leads to severe environmental concerns and is therefore a stumbling block envisioning their large-scale application. Aiming for the retention of favorable electro-optical properties, tin (Sn) has been considered the most likely substitute. Preliminary studies have however shown that Sn-based perovskites are highly unstable and, moreover, Sn is also enlisted as a harmful chemical, with similar concerns regarding environment and health. To bring more clarity into the appropriateness of both metals in perovskite solar cells, we provide a case study with systematic comparison regarding the environmental impact of Pb- and Sn-based perovskites, using zebrafish (Danio Rerio) as model organism. Uncovering an unexpected route of intoxication in the form of acidification, it is shown that Sn based perovskite may not be the ideal Pb surrogate.
9 December 1988 in Science
Journal Article
RSRoland Schüle
Roland Schüle
Marc MullerCKChristian Kaltschmidt
Christian Kaltschmidt
RRRainer Renkawitz
Rainer Renkawitz
Progesterone (PRE) or glucocorticoid receptor (GRE) DNA binding sites are often found clustered with binding sites for other transcription factors. Individual protein binding sites were tested without the influence of adjacent factors by analyzing isolated combinations of several transcription factor binding sites with PREs or GREs. All show strong synergistic effects on steroid induction. The degree of synergism is inversely related to the strength of the GRE. Thus, a steroid responsive unit can be composed of several modules that, if positioned correctly, act synergistically.
1 March 1988 in Nature
Journal Article
RSRoland Schüle
Roland Schüle
Marc MullerHOHidetsugu Otsuka-Murakami
Hidetsugu Otsuka-Murakami
RRRainer Renkawitz
Rainer Renkawitz
1 October 2001 in Molecular and Cellular Biology
Journal Article
HPHélÈNE Pendeville
HélÈNE Pendeville
NCNick Carpino
Nick Carpino
JMJean-Christophe Marine
Jean-Christophe MarineYTYutaka Takahashi
Yutaka Takahashi
Marc MullerJCJohn L. Cleveland
John L. Cleveland +1
Overexpression and inhibitor studies have suggested that the c-Myc target gene for ornithine decarboxylase (ODC), the enzyme which converts ornithine to putrescine, plays an important role in diverse biological processes, including cell growth, differentiation, transformation, and apoptosis. To explore the physiological function of ODC in mammalian development, we generated mice harboring a disrupted ODC gene.ODC-heterozygous mice were viable, normal, and fertile. Although zygotic ODC is expressed throughout the embryo prior to implantation, loss of ODC did not block normal development to the blastocyst stage. Embryonic day E3.5 ODC-deficient embryos were capable of uterine implantation and induced maternal decidualization yet failed to develop substantially thereafter. Surprisingly, analysis of ODC-deficient blastocysts suggests that loss of ODC does not affect cell growth per se but rather is required for survival of the pluripotent cells of the inner cell mass. Therefore, ODC plays an essential role in murine development, and proper homeostasis of polyamine pools appears to be required for cell survival prior to gastrulation.
1 October 2011 in Toxicology Letters
Journal Article
CFC. Frizzell
C. Frizzell
DND. Ndossi
D. Ndossi
SVS. Verhaegen
S. Verhaegen
EDE. Dahl
E. Dahl
GEGunnar Sundstøl Eriksen
Gunnar Sundstøl Eriksen
Lisa Connolly +4
About Me
Marc Muller is currently a Senior Research Associate at the “Fonds National de Recherche Scientifique”, Principal Investigator at the GIGA Research Center, and Lecturer of Molecular and Cellular Biology at the University of Liège (ULG). He obtained his MSc in Chemical Sciences at the University of Liège, Belgium, in 1980 and was awarded in 1986 a Ph.D. in Chemical Sciences, specializing in DNA repair mechanisms at the same University of Liège. As a postdoctoral scientist in Germany, he was involved in studying gene regulation in various systems, before taking his present position and focusing on zebrafish embryo development and toxicology. He is the coordinator of the Biomedaqu project, supervisor of ESR2, and co-supervisor of ESR1. These projects aim to use the zebrafish as a model system for skeletal pathologies in humans and in fish. His research focuses on Developmental Biology, using the zebrafish as a model system and using molecular and genetic approaches. His main focus is on bone development and homeostasis, and his group is also studying more general perturbations of zebrafish physiology by physical (changes in gravity) or chemical treatments. Recent studies include studying the effects of food additives, endocrine disruptors, and mixtures thereof to better understand the intricate interactions between the various signaling pathways involved.