Cesarina Giallongo is an Assistant Professor of Blood Diseases at the University of Catania. Her research primarily concerns the role of the tumor microenvironment in the pathogenesis and progression of hematological malignancies. Within this context, she has investigated tumor-induced immunosuppressive mechanisms, cytokine networks, and metabolic changes in the tumor microenvironment. She has evaluated the complex crosstalk between mesenchymal stromal cells (MSCs), myeloid-derived suppressor cells, and leukemic cells. Her ongoing research projects include mitochondrial transfer between MSCs and myeloma cells as a potential mechanism that induces chemoresistance, improving the mitochondrial fitness of tumor cells. Moreover, she studied tumor–stroma metabolic coupling and its link to epigenetic changes in myelodysplastic syndrome (MDS) and the leukemia microenvironment.