Ira Jacobs

Dr. Ira Jacobs

1. Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON M5S 2W6, Canada
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Research Focus & Metrics

Academic Career Length

13Years (2014-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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6 May 2019 in Nutrition & Metabolism
Verified
Journal Article
Open access
PDF file
IMIva Mandic
Iva Mandic
MAMavra Ahmed
Mavra Ahmed
Shawn G. RhindShawn G. Rhind
Shawn G. Rhind
LGLen Goodman
Len Goodman
MLMary L’abbe
Mary L’abbe
Ira JacobsIra Jacobs
Ira Jacobs
It is not clear whether the frequently reported phenomenon of exercise-induced anorexia is exacerbated or blunted in warm or cold environments. Therefore, this study investigated the effects of exercise in three different environmental temperatures vs. rest, on perceptions of appetite, appetite regulating hormones, and food intake. In a randomized repeated-measures design, 18 Canadian Armed Forces members (14 male, 4 female) completed four 8-h trials in a thermally-controlled chamber: one 8-h resting trial at 21 °C (Sedentary); and three trials where participants completed two 2-h circuits of standardized military tasks interspersed with two 2-h rest periods, once at 30 °C (Hot), once at 21 °C (Temperate), and once at − 10 °C (Cold). Participants consumed military field rations ad libitum and had their appetite assessed with visual analogue scales. Plasma concentrations of GLP-1, PYY, acylated ghrelin, and leptin were also determined. Appetite was perceived as being suppressed in the heat compared to the cold (p < 0.05). While neither exercise nor environmental temperature altered circulating GLP-1 levels, exercise in all environments increased blood concentrations of PYY (p < 0.05). Leptin concentrations were elevated in the heat and diminished in the cold (p < 0.05), and acylated ghrelin concentrations were affected by both exercise and ambient temperature resulting in Sedentary = Cold>Temperate = Hot (p < 0.05). Contrary to the changes in appetite perceptions and hormonal concentrations, dietary intake was not different between conditions (p > 0.05). Relative energy intake (total 24 h energy intake minus 24 h energy expenditure) on the other hand, was significantly higher during the Sedentary condition than it was during any of the active conditions (p < 0.05). Most (83%) of the participants were in a positive energy balance during the Sedentary condition, whereas during most (80%) of the active conditions (Hot, Temperate, Cold) participants were in a negative energy balance. In this study where food was freely available, variations in ambient temperature, exercise vs. rest, appetite-regulating hormone concentrations, and subjective appetite sensation were not associated with any changes in dietary intake within 24-h of acute, prolonged exercise.

29 April 2021 in Frontiers in Physiology
Verified
Journal Article
Open access
PDF file
LOLiam O'Brien
Liam O'Brien
Ira JacobsIra Jacobs
Ira Jacobs
Ischemic preconditioning (IPC) has been repeatedly reported to augment maximal exercise performance over a range of exercise durations and modalities. However, an examination of the relevant literature indicates that the reproducibility and robustness of ergogenic responses to this technique are variable, confounding expectations about the magnitude of its effects. Considerable variability among study methodologies may contribute to the equivocal responses to IPC. This review focuses on the wide range of methodologies used in IPC research, and how such variability likely confounds interpretation of the interactions of IPC and exercise. Several avenues are recommended to improve IPC methodological consistency, which should facilitate a future consensus about optimizing the IPC protocol, including due consideration of factors such as: location of the stimulus, the time between treatment and exercise, individualized tourniquet pressures and standardized tourniquet physical characteristics, and the incorporation of proper placebo treatments into future study designs.

27 February 2017 in Nutrients
Verified
Journal Article
Open access
PDF file
MAMavra Ahmed
Mavra Ahmed
IMIva Mandic
Iva Mandic
WLWendy Lou
Wendy Lou
LGLen Goodman
Len Goodman
Ira JacobsIra Jacobs
Ira Jacobs
Mary LabbeMary Labbe
Mary Labbe
The collection of accurate dietary intakes using traditional dietary assessment methods (e.g., food records) from military personnel is challenging due to the demanding physiological and psychological conditions of training or operations. In addition, these methods are burdensome, time consuming, and prone to measurement errors. Adopting smart-phone/tablet technology could overcome some of these barriers. The objective was to assess the validity of a tablet app, modified to contain detailed nutritional composition data, in comparison to a measured food intake/waste method. A sample of Canadian Armed Forces personnel, randomized to either a tablet app (n = 9) or a weighed food record (wFR) (n = 9), recorded the consumption of standard military rations for a total of 8 days. Compared to the gold standard measured food intake/waste method, the difference in mean energy intake was small (−73 kcal/day for tablet app and −108 kcal/day for wFR) (p > 0.05). Repeated Measures Bland-Altman plots indicated good agreement for both methods (tablet app and wFR) with the measured food intake/waste method. These findings demonstrate that the tablet app, with added nutritional composition data, is comparable to the traditional dietary assessment method (wFR) and performs satisfactorily in relation to the measured food intake/waste method to assess energy, macronutrient, and selected micronutrient intakes in a sample of military personnel.

2 June 2020 in Nutrients
Verified
Journal Article
Open access
PDF file
MAMavra Ahmed
Mavra Ahmed
IMIva Mandic
Iva Mandic
EDElliot Desilets
Elliot Desilets
ISIngrid Smith
Ingrid Smith
WSWendy Sullivan-Kwantes
Wendy Sullivan-Kwantes
Mary LabbeMary Labbe
Mary Labbe
Operating in temperature extremes frequently leads to a discrepancy in energy balance. Investigating the effects of operating in extreme cold temperatures on metabolic requirements has not been well described in Canadian Armed Forces (CAF) personnel. The objective was to accurately assess energy deficits using the “gold standard” methodology for measuring energy intake (EI) and energy expenditure (EE). Nutritional intake of a convenience sample of 10 CAF Class A Reservists, completing a basic military qualification (land) course under winter weather conditions, was assessed using the daily measured food intake/food waste collections. EE was measured by the doubly-labelled water method. Average EI was 2377 ± 1144 kcal/day, which was below the EE (4917 ± 693 kcal/day), despite having ~5685 kcal available in the field rations. A significant body weight loss of 2.7% was associated with the average daily energy deficit of 2539 ± 1396 kcal. As a result, participants demonstrated voluntary anorexia. Such results may have important implications for the impairment of performance and health under longer duration operations.

16 August 2019 in Military Medical Research
Verified
Journal Article
Open access
PDF file
MAMavra Ahmed
Mavra Ahmed
IMIva Mandic
Iva Mandic
WLWendy Lou
Wendy Lou
LGLen Goodman
Len Goodman
Ira JacobsIra Jacobs
Ira Jacobs
Mary LabbeMary Labbe
Mary Labbe
Dietary Reference Intakes are used to guide the energy intake of the Canadian Armed Forces (CAF) field rations provided to military personnel deployed for training or operations. However, the high energy expenditures likely to occur under harsh environmental/metabolically challenging deployment conditions may not be adequately considered. This study examined the Ad libitum energy and nutrient intakes of CAF personnel (n = 18) consuming field rations in a resting thermoneutral environment and during a day of standardized strenuous infantry activities at varying environmental temperatures. Dietary intake was assessed using a measured food intake/food waste method during the experimental treatment and for 6 h after treatment. Four treatments were administered in a randomized counterbalanced design: exercise (as standardized infantry activities) in the heat (30 °C), exercise in the cold (− 10 °C), exercise in temperate thermoneutral (21 °C) air temperatures and a resting (sedentary) trial (21 °C). The average Ad libitum consumption of field rations was 70% of the provided total energy (2776 ± 99 kcal/8 h) during all treatments. Even with an acute challenge of increased energy expenditure and temperature stress in the simulated field conditions, participants’ energy intakes (1985 ± 747 kcal/8 h) under hot, cold and temperate treatments did not differ from energy intake during the sedentary condition (1920 ± 640 kcal/8 h). Participants’ energy intakes (1009 ± 527 kcal/6 h) did not increase during the 6 h posttreatment period when the stresses of the strenuous physical activities and the harsh environmental temperatures had subsided. These results should be considered when planning the provision of field rations for CAF personnel expected to be engaged in strenuous physical activities with prolonged exposure to temperature extremes.

28 November 2022 in Frontiers in Physiology
Verified
Journal Article
Open access
LOLiam O'Brien
Liam O'Brien
Ira JacobsIra Jacobs
Ira Jacobs
Ischemic preconditioning (IPC) has been reported to augment exercise performance, but there is considerable heterogeneity in the magnitude and frequency of performance improvements. Despite a burgeoning interest in IPC as an ergogenic aid, much is still unknown about the physiological mechanisms that mediate the observed performance enhancing effects. This narrative review collates those physiological responses to IPC reported in the IPC literature and discusses how these responses may contribute to the ergogenic effects of IPC. Specifically, this review discusses documented central and peripheral cardiovascular responses, as well as selected metabolic, neurological, and perceptual effects of IPC that have been reported in the literature.