Karma Fathalla

Dr. Karma Fathalla


Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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8 July 2020 in Applied Sciences
Verified
Journal Article
Open access
PDF file
Mohamed Ramzy IbrahimMohamed Ramzy Ibrahim
Mohamed Ramzy Ibrahim
KFKarma Fathalla
Karma Fathalla
SYSherin M. Youssef
Sherin M. Youssef
Optical Coherence Tomography (OCT) imaging has major advantages in effectively identifying the presence of various ocular pathologies and detecting a wide range of macular diseases. OCT examinations can aid in the detection of many retina disorders in early stages that could not be detected in traditional retina images. In this paper, a new hybrid computer-aided OCT diagnostic system (HyCAD) is proposed for classification of Diabetic Macular Edema (DME), Choroidal Neovascularization (CNV) and drusen disorders, while separating them from Normal OCT images. The proposed HyCAD hybrid learning system integrates the segmentation of Region of Interest (RoI), based on central serious chorioretinopathy (CSC) in Spectral Domain Optical Coherence Tomography (SD-OCT) images, with deep learning architectures for effective diagnosis of retinal disorders. The proposed system assimilates a range of techniques including RoI localization and feature extraction, followed by classification and diagnosis. An efficient feature fusion phase has been introduced for combining the OCT image features, extracted by Deep Convolutional Neural Network (CNN), with the features extracted from the RoI segmentation phase. This fused feature set is used to predict multiclass OCT retina disorders. The proposed segmentation phase of retinal RoI regions adds substantial contribution as it draws attention to the most significant areas that are candidate for diagnosis. A new modified deep learning architecture (Norm-VGG16) is introduced integrating a kernel regularizer. Norm-VGG16 is trained from scratch on a large benchmark dataset and used in RoI localization and segmentation. Various experiments have been carried out to illustrate the performance of the proposed system. Large Dataset of Labeled Optical Coherence Tomography (OCT) v3 benchmark is used to validate the efficiency of the model compared with others in literature. The experimental results show that the proposed model achieves relatively high-performance in terms of accuracy, sensitivity and specificity. An average accuracy, sensitivity and specificity of 98.8%, 99.4% and 98.2% is achieved, respectively. The remarkable performance achieved reflects that the fusion phase can effectively improve the identification ratio of the urgent patients’ diagnostic images and clinical data. In addition, an outstanding performance is achieved compared to others in literature.

25 May 2021 in Journal of Ambient Intelligence and Humanized Computing
Verified
Journal Article
Closed access
PDF file
Mohamed Ramzy IbrahimMohamed Ramzy Ibrahim
Mohamed Ramzy Ibrahim
SYSherin M. Youssef
Sherin M. Youssef
KFKarma Fathalla
Karma Fathalla

Verified
Journal Article
Open access
PDF file
OAOmar Adel
Omar Adel
KFKarma Fathalla
Karma Fathalla
AAAhmed Abouelfarag
Ahmed Abouelfarag
Emotion recognition is crucial in artificial intelligence, particularly in the domain of human–computer interaction. The ability to accurately discern and interpret emotions plays a critical role in helping machines to effectively decipher users’ underlying intentions, allowing for a more streamlined interaction process that invariably translates into an elevated user experience. The recent increase in social media usage, as well as the availability of an immense amount of unstructured data, has resulted in a significant demand for the deployment of automated emotion recognition systems. Artificial intelligence (AI) techniques have emerged as a powerful solution to this pressing concern in this context. In particular, the incorporation of multimodal AI-driven approaches for emotion recognition has proven beneficial in capturing the intricate interplay of diverse human expression cues that manifest across multiple modalities. The current study aims to develop an effective multimodal emotion recognition system known as MM-EMOR in order to improve the efficacy of emotion recognition efforts focused on audio and text modalities. The use of Mel spectrogram features, Chromagram features, and the Mobilenet Convolutional Neural Network (CNN) for processing audio data are central to the operation of this system, while an attention-based Roberta model caters to the text modality. The methodology of this study is based on an exhaustive evaluation of this approach across three different datasets. Notably, the empirical findings show that MM-EMOR outperforms competing models across the same datasets. This performance boost is noticeable, with accuracy gains of an impressive 7% on one dataset and a substantial 8% on another. Most significantly, the observed increase in accuracy for the final dataset was an astounding 18%.

21 June 2022 in Applied Sciences
Verified
Journal Article
Open access
PDF file
KFKarma Fathalla
Karma Fathalla
SYSherin M. Youssef
Sherin M. Youssef
NMNourhan Mohammed
Nourhan Mohammed
Lung Cancer is one of the primary causes of cancer-related deaths worldwide. Timely diagnosis and precise staging are pivotal for treatment planning, and thus can lead to increased survival rates. The application of advanced machine learning techniques helps in effective diagnosis and staging. In this study, a multistage neurobased computational model is proposed, DETECT-LC learning. DETECT-LC handles the challenge of choosing discriminative CT slices for constructing 3D volumes, using Haralick, histogram-based radiomics, and unsupervised clustering. ALT-CNN-DENSE Net architecture is introduced as part of DETECT-LC for voxel-based classification. DETECT-LC offers an automatic threshold-based segmentation approach instead of the manual procedure, to help mitigate this burden for radiologists and clinicians. Also, DETECT-LC presents a slice selection approach and a newly proposed relatively light weight 3D CNN architecture to improve existing studies performance. The proposed pipeline is employed for tumor phenotyping and staging. DETECT-LC performance is assessed through a range of experiments, in which DETECT-LC attains outstanding performance surpassing its counterparts in terms of accuracy, sensitivity, F1-score and Area under Curve (AuC). For histopathology classification, DETECT-LC average performance achieved an improvement of 20% in overall accuracy, 0.19 in sensitivity, 0.16 in F1-Score and 0.16 in AuC over the state of the art. A similar enhancement is reached for staging, where higher overall accuracy, sensitivity and F1-score are attained with differences of 8%, 0.08 and 0.14.

1 January 2021 in Health Informatics Journal
Verified
Journal Article
Open access
PDF file
MNMohamed A. Nabil
Mohamed A. Nabil
AAAnsam Akram
Ansam Akram
KFKarma Fathalla
Karma Fathalla
Autism Spectrum Disorder (Autism) is a developmental disorder that impedes the social and communication capabilities of a person through out his life. Early detection of autism is critical in contributing to better prognosis. In this study, the use of home videos to provide accessible diagnosis is investigated. A machine learning approach is adopted to detect autism from home videos. Feature selection and state-of-the-art classification methods are applied to provide a sound diagnosis based on home video ratings obtained from non-clinicians feedback. Our models results indicate that home videos can effectively detect autistic group with True Positive Rate reaching 94.05% using Support Vector Machines and backwards feature selection. In this study, human-interpretable models are presented to elucidate the reasoning behind the classification process and its subsequent decision. In addition, the prime features that need to be monitored for early autism detection are revealed.

30 January 2024 in IEEE Access
Verified
Journal Article
Open access
DSDoaa Shoieb
Doaa Shoieb
AYAhmed Younes
Ahmed Younes
SYSherin M. Youssef
Sherin M. Youssef
KFKarma Fathalla
Karma Fathalla
Cardiac pathology classification (CPC) based on the volumetric features of three key heart structures can be extracted from segmented cardiac cine magnetic resonance imaging (CMRI) sequences. Machine learning models have recently become very effective tools for handling these problems. Hybrid quantum methods can be employed to enhance the capacities of classical machine learning models. Here, we propose a hybrid quantum multiclass cardiac pathologies classification (HQMC-CPC) model. In the proposed model, discriminative features are extracted to characterize the shape and function of the heart, combining the clinical features, patient features, and radiomics features. In the proposed quantum circuits, all variational parameters are trainable, and the enhanced variational quantum circuit is employed for efficient neural network learning. Using only thirty feature values as input, we propose a hybrid quantum multiclass cardiac pathologies classification (HQMC-CPC) model based on the proposed modified hardware efficient ansatz (MHEA). The proposed model achieves promising results in training and testing with the Automatic Cardiac Diagnosis Challenge (ACDC 2017) dataset. Experimental results showed that the proposed HQMC-CPC model is able to classify different cardiac pathologies with an average minimum performance gap of 3.19%. The average maximum improvement in terms of accuracy in cardiac pathology classification is 7.77%. Moreover, the proposed HQMC-CPC speeds up the testing process by around 60% and 40% compared to the classical classifiers and well-established HEA respectively.