Sebastian Hardt

Dr. Sebastian Hardt

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orcid

Research Focus & Metrics

Academic Career Length

20Years (2007-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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6 February 2021 in Archives of orthopaedic and trauma surgery
Verified
Journal Article
Open access
PDF file
Henrik C. BäckerHenrik C. Bäcker
Henrik C. Bäcker
CWChia H. Wu
Chia H. Wu
MSMatthias R. G. Schulz
Matthias R. G. Schulz
TWThomas Sanjay Weber-Spickschen
Thomas Sanjay Weber-Spickschen
CPCarsten Perka
Carsten Perka
SHSebastian Hardt
Sebastian Hardt
Introduction: New app-based programs for postoperative rehabilitation have been developed, but no long-term study has been published to date. Thus, a prospective randomized control trial with 2-year follow-up was performed to evaluate the effectiveness of app-based rehabilitation (GenuSport) compared to a control group after total knee arthroplasty (TKA). Methods: Between April and October 2016, 60 patients were enrolled in the study. Twenty-five patients were lost to follow-up, leaving 35 patients undergoing TKA for inclusion. In this group, twenty patients received app-based exercise program and 15 were randomized to the control group. The mean age was 64.37 ± 9.32 years with a mean follow-up of 23.51 ± 1.63 months. Patients in the app group underwent an app-based knee training starting on the day of surgery; whereas, patients in the control group underwent regular physiotherapy. Functional outcome scores using the Knee Injury and Osteoarthritis Outcome Score (KOOS), Knee Society Score (KSS) and VAS of pain were analyzed. Results: In the short term, significant differences between the app group and control group in time of 10-m walk (19.66 ± 7.80 vs. 27.08 ± 15.46 s; p = 0.029), VAS pain at rest and activity (2.65 ± 0.82 vs. 3.57 ± 1.58, respectively 4.03 ± 1.26 vs. 5.05 ± 1.21; p < 0.05) were observed. In the long term, a variety of different tendencies was found, highest in KSS Function with 76.32 ± 16.49 (app group) vs. 67.67 ± 16.57 (control group) (p = 0.130). Additionally, patients in the app group required less painkillers (10.0% vs. 26.7%) and more likely to participate in sports (65.0% vs. 53.3%). Conclusions: An app-based knee trainer is a promising tool in improving functional outcomes such as KSS function score and VAS after TKA. Level of evidence: Level II, prospective randomized control trial.

27 March 2018 in Knee Surgery, Sports Traumatology, Arthroscopy
Verified
Journal Article
Closed access
PDF file
SHSebastian Hardt
Sebastian Hardt
MSMatthias R. G. Schulz
Matthias R. G. Schulz
TPTilman Pfitzner
Tilman Pfitzner
GWGeorgi Wassilew
Georgi Wassilew
HHHauke Horstmann
Hauke Horstmann
TWThomas Sanjay Weber-Spickschen
Thomas Sanjay Weber-Spickschen

27 September 2021 in HIP International
Verified
Journal Article
Open access
PDF file
SASuhaib JS. Ahmad
Suhaib JS. Ahmad
GGGregor M Giebel
Gregor M Giebel
CPCarsten Perka
Carsten Perka
SMSebastian Meller
Sebastian Meller
Matthias PumbergerMatthias Pumberger
Matthias Pumberger
CKChristian Konrads
Christian Konrads
Background: Periacetabular osteotomy (PAO) has become a popular procedure for re-orientation of the acetabulum in patients with a developmental pathomorphology. Since its first description by Reinhold Ganz in 1988, many institutions worldwide have adopted the procedure for the treatment of developmental hip dysplasia (DDH) and have subsequently reported their results. The aim of this study was to provide a meta-analysis of the likelihood of long-term survival of a dysplastic hip after PAO. Methods: A systematic literature review was conducted using Medline, Cochrane and “Web of Science” databases to identify articles reporting survival estimates for PAO in patients with DDH. To be included in the analysis, studies had to include patient cohorts aged <40 years, with Osteoarthritis grade < Tönnis III and no form of neuromuscular dysplasia. Adjustment for cohort overlap was performed. Quality assessment included level of evidence (LOE) according to the oxford center for LOE criteria and the “Methodological index for non-randomized studies (MINORS)”. After data extraction, a random-effects meta-analytical model was applied to provide weighted mean estimates of survival at 5 years, 10 years, 15 years and 20 years. Results: Nine relevant articles included 2268 dysplastic hips that underwent PAO in 9 institutions. Of the included studies, 5 presented level III evidence and 4 presented level IV evidence. The MINORS score was 11 for 3 studies, 12 for 4 studies and 13 for 2 studies. The 5-year survival after PAO was 96.1% (95% CI, 94.9–97.3), the 10-year survival was 91.3% (95% CI, 87.7–94.8), 15-year survival 85.0% (95% CI, 78.9–91.1), 20-year survival 67.6% (95% CI, 53.9–81.3). Conclusions: The results provide a representative survival estimate of a dysplastic hip after PAO based on global evidence. This should provide clinicians and patients with an adequate reflection of prognostic expectations after this kind of surgery.

1 January 2021 in Journal of Clinical Orthopaedics and Trauma
Verified
Journal Article
Closed access
Henrik C. BäckerHenrik C. Bäcker
Henrik C. Bäcker
CWChia H. Wu
Chia H. Wu
MMMauro Maniglio
Mauro Maniglio
SWSophie Wittekindt
Sophie Wittekindt
SHSebastian Hardt
Sebastian Hardt
CPCarsten Perka
Carsten Perka

1 December 2020 in Archives of orthopaedic and trauma surgery
Verified
Journal Article
Open access
PDF file
TVTu-Lan Vu-Han
Tu-Lan Vu-Han
SHSebastian Hardt
Sebastian Hardt
RAR. Ascherl
R. Ascherl
CGC. Gwinner
C. Gwinner
CPCarsten Perka
Carsten Perka
Introduction: Total hip arthroplasty (THA) surgeries are expected to exponentially increase in the upcoming years, likely because of the overall broader indication of THAs. With these developments, an increasing number of younger (< 50 years) and active patients will receive surgical interventions, and expectations for an active lifestyle will accordingly increase. In addition, surgeons now have a growing array of techniques and implant materials to choose from. Despite these developments, evidence to provide the best standard-of-care to patients with high expectations for return to sports (RTS) is scarce and urgently needed. What recommendations do arthroplasty surgeons currently make to patients with high return to sports expectations, what factors may influence their recommendations and what surgical techniques and implant specifications are considered favorable in the treatment of patients with a more active lifestyle? This study was conducted to analyze the current recommendations, patient assessment, and patient counseling after THA to identify trends and relevant factors for surgical decision-making in patients with high-RTS expectations.Material and methods: We designed a questionnaire comprising five general items and 19 specific items that included 46 sub-items for hip arthroplasty and conducted a survey among 300 German surgeons specialized in arthroplasty at the German Arthroplasty Society (AE) to assess expert opinions, recommendations, surgical decision-making, and patient counseling for patients with high expectations for RTS after THA.Results: The majority of surgeons (81.9%) were in favor of RTS after THA. Risks associated with sports after THA were considered minimal (1%), with periprosthetic fractures ranking highest, followed by hip dislocation and polyethylene wear. Some surgical decision-making was influenced by high-RTS expectations in regard to implant fixation, stem type, femoral head diameter, and bearing-surface tribology. We observed an increasingly liberal counseling of patients for high-impact sports.Conclusion: With the improvement of implants and surgical techniques, surgeons are more willing to encourage patients to adopt a more active lifestyle. However, the true long-term limitations need further investigation in future studies.Level of evidence: 5 Expert opinions.

13 March 2022 in Metabolic Engineering
Verified
Journal Article
Closed access
ADAlexandra Damerau
Alexandra Damerau
MKMarieluise Kirchner
Marieluise Kirchner
MPMoritz Pfeiffenberger
Moritz Pfeiffenberger
LELisa Ehlers
Lisa Ehlers
DNDuc Ha Do Nguyen
Duc Ha Do Nguyen
Timo GaberTimo Gaber
Timo Gaber