To determine the epidemiological profile and risk factors of voluntary poisoning by pesticides. A retrospective analysis was conducted of all cases of voluntary poisoning by pesticides registered at the AntiPoison and Pharmacovigilance Center of Morocco between January 2008 and December 2014. During the study period, 2,690 cases of acute pesticide poisoning were registered. The region of Rabat-Salé-Zemmour-Zaer accounted for the largest proportion, with 598 cases. The average age of the patients was 24.63±10.29 years. The sex ratio (female-to-male) was 0.45. Adults and teenagers were most affected by this type of poisoning, with 1,667 cases (62.0%) and 806 cases (30.0%), respectively. Suicide attempts accounted for 98.4% of the cases (2,469 cases). Pesticide poisoning occurred more often in urban zones (64.8%). Insecticides were incriminated in 14.0% of cases, with a mortality rate of 4.2%. Among the 1,635 patients for whom the outcomes were known, 154 died, corresponding to a mortality rate of 5.7%. Voluntary intoxication by pesticides presents a real scourge that affects public health, and in this study, we developed an epidemiological profile of this phenomenon. Nevertheless, this study has limitations in that it did not evaluate the impact of the socioeconomic and psychological factors that are important contributors to this type of poisoning.

Context: Infertility is one of the most painful experiences that can have a negative impact in many areas of an individual’s life. Providing quality care to infertile couples requires health professionals to explore their experiences and needs to plan effective supportive interventions. Objectives: To explore the experiences and needs of Moroccan infertile couples in Assisted Reproductive Technology. Material and Methods: This is a qualitative exploratory study. It involves 40 infertile couples (men and women) and 5 health professionals as key informants. Infertile couples were selected among those attending the first public center for Assisted Reproductive Technology in Morocco located in Rabat during the period 2017-2018. In-depth unstructured interviews, field notes were used with couples and semi-structured interviews with health professionals. The analysis of the interview data was based on a conventional content analysis method. Results: Five types of needs were identified among infertile Moroccan couples, namely: i. Infertility and social support; ii. Infertility and financial support; iii. Infertility and spiritual support; iv. Infertility and informational support; v. Infertility and emotional support. Conclusion: Infertile moroccan couples experienced many emotional, psychosocial and economic difficulties that can negatively affect their quality of life. Thus, to meet the needs and expectations of these couples alongside their medical treatment, it’s necessary to develop couple-centered approaches, which can improve their quality of life, treatment outcomes and mitigate negative psychosocial consequences. Bangladesh Journal of Medical Science Vol.19(4) 2020 p.697-704

Background: Pharmacovigilance is one of the priority programs of the World Health Organization, with the aim of detecting the adverse effects of drugs. Morocco is one of the countries open to the world and was the first Arab and African country to participate in the international pharmacovigilance program. The purpose of this study is to develop and to validate a reliable and reasonable questionnaire, to measure knowledge and practices related to pharmacovigilance among health professionals in Morocco. Materials and Methods: This is a cross-sectional study that took place between January and March 2018. The study was based on a questionnaire. Pharmacovigilance experts validated the questionnaire and the final instrument was applied to health professionals practicing in different hospitals in Morocco. The statistical validation of the questionnaire is based on the calculation of the Cronbach Coefficient Index and a factor analysis. Results: The study involved 262 health professionals, including 39% of physicians, 35% of pharmacists and 26% of nurses. The average age of the participants was 35.2 ± 8.4 years old. The Cronbach alpha value of the set of items was 0.7, similarly, the calculation of Cronbach’s alpha showed a homogeneity of the different dimensions of the questionnaire used this for knowledge (α = 0.6) and practices related to pharmacovigilance (α = 0.6). On the knowledge side, 65% of participants correctly answered the definition of pharmacovigilance, 81% were aware of its primary objective. We have noted that 52% of health workers, were aware of the existence of a national pharmacovigilance program in Morocco and 71% of the existence of the poison control center and pharmacovigilance of Morocco. The questionnaire has also shown that 28% of participants have reported an adverse reaction to the Poison Control and Pharmacovigilance Center of Morocco. Conclusion: Results showed that questionnaire is a well-structured, objective, valid and reliable in the Moroccan context, the questionnaire could be an instrument to assess knowledge and practice in Pharmacovigilance. Key words: Validation, Questionnaire, Pharmacovigilance, Health Professionals, Morocco.

Introduction: L’activité physique est généralement altérée chez le patient hémodialysé chronique. Les études confirment le bénéfice du maintien ou de la reprise de l’activité physique chez ces patients. Pour cette raison, notre étude vise à évaluer la sédentarité à l’aide d’un score d’activité physique de DIJON chez les hémodialysés chroniques et à identifier les facteurs liés à une baisse de l’activité physique chez eux. Méthodes: Nous avons mené, durant le mois de février 2019, une étude transversale descriptive et analytique chez les patients hémodialysés chroniques de deux centres d’hémodialyse. Nous avons utilisé le questionnaire de Dijon pour mesurer l’AP en prenant en compte les activités quotidiennes, sportives ou de loisirs. Les valeurs de référence du niveau d’AP sont 0–10 (faible), 10–20 (moyen), et 20–30 (élevé). Résultats obtenus ou attendus Notre étude a inclus 127 patients. L’âge moyen était de 51 ± 15 ans avec une prédominance féminine. Le niveau d’activité physique global était élevé à 23,9 ± 2,54 chez 30 % des patients, moyen à 14 ± 2,9 chez 22 % des patients et faible à 7,48 ± 2,08 chez 48 % des hémodialysés. L’analyse en régression linéaire multiple montre que les variables expliquant le score de DIJON dans notre population sont par ordre de contribution : l’ancienneté en hémodialyse (β = −0,283 ; t = −4,196 ; p < 0,001), l’urémie pré-dialytique (β = 0,270 ; t = 3,987 ; p < 0,001), la néphroangiosclérose (β = −0,219 ; t = −3,267 ; p = 0,001), la profession (β = −0,229 ; t = −3,305 ; p = 0 ?001), le sexe féminin (β = −0,190 ; t = −2,793 ; p = 0 ?002), l’anémie (β = −0,229 ; t = −3,172 ; p = 0,002) et le tabagisme (β = −0,190 ; t = 2,793 ; p = 0,006). Conclusion: Nos résultats montrent que le niveau d’activité physique est lié à de nombreux paramètres dont certains sont modifiables. La prescription d’un programme adapté et personnalisé améliorerait le pronostic lié aux comorbidités et à la qualité de vie de nos patients.