Mahmoud El-Readi

Dr. Mahmoud El-Readi

Biochemistry Department, Faculty of Medicine, Umm Al-Qura University, KSA; Biochemistry Department, Faculty of Pharmacy, Al-Azhar University, Assuit, Egypt
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Biography

- Major research interests are in the areas of Biochemical and molecular markers in the diagnosis and therapy of chronic diseases - The roles played by oxidative stress, inflammation, and hormonal individuals' profiles in chronic diseases, especially DM, hypertension, liver, and kidney diseases. - Molecular Mechanisms of Anticancer drugs - Drug discovery from plants and marine sources. My research spans a wide range of objects, starting from the biochemical activities (anticancer, antioxidant, anti-inflammatory, and anti-infective) to molecular mechanisms of isolated phytochemicals and medicinal plants and marine products and their role in cancer prevention. - The specific interests are the synergistic interactions of phytochemicals combination and their ability to reverse multidrug resistance in cancer cells and explore the mechanism of P-glycoprotein, MRP, BCRP...etc.). - The cellular, actions (apoptosis, DNA fragmentation, cell membrane interactions, drug efflux pump inhibition, modulation of metabolic enzymes (e.g., CYPs and GST) and ABC-transporters (e.g. molecular and biochemical bases of chronic diseases and their effects on the pathological conditions

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