Andrew Marcantonio

Dr. Andrew Marcantonio


Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
1 June 2023 in JAMA Network Open
Verified
Journal Article
Open access
PDF file
ESEmil H. Schemitsch
Emil H. Schemitsch
LNLauren L. Nowak
Lauren L. Nowak
ASArndt Peter Schulz
Arndt Peter Schulz
OBOle Brink
Ole Brink
RPRudolf W. Poolman
Rudolf W. Poolman
GFgang feng
gang feng
Importance: Fractures of the hip have devastating effects on function and quality of life. Intramedullary nails (IMN) are the dominant implant choice for the treatment of trochanteric fractures of the hip. Higher costs of IMNs and inconclusive benefit in comparison with sliding hip screws (SHSs) convey the need for definitive evidence.Objective: To compare 1-year outcomes of patients with trochanteric fractures treated with the IMN vs an SHS.Design, Setting, and Participants: This randomized clinical trial was conducted at 25 international sites across 12 countries. Participants included ambulatory patients aged 18 years and older with low-energy trochanteric (AO Foundation and Orthopaedic Trauma Association [AO/OTA] type 31-A1 or 31-A2) fractures. Patient recruitment occurred between January 2012 and January 2016, and patients were followed up for 52 weeks (primary end point). Follow-up was completed in January 2017. The analysis was performed in July 2018 and confirmed in January 2022.Interventions: Surgical fixation with a Gamma3 IMN or an SHS.Main Outcomes and Measures: The primary outcome was health-related quality of life (HRQOL), measured by the EuroQol–5 Dimension (EQ5D) at 1-year postsurgery. Secondary outcomes included revision surgical procedure, fracture healing, adverse events, patient mobility (measured by the Parker mobility score), and hip function (measured by the Harris hip score).Results: In this randomized clinical trial, 850 patients were randomized (mean [range] age, 78.5 [18-102] years; 549 [64.6% female) with trochanteric fractures to undergo fixation with either the IMN (n = 423) or an SHS (n = 427). A total of 621 patients completed follow-up at 1 year postsurgery (304 treated with the IMN [71.9%], 317 treated with an SHS [74.2%]). There were no significant differences between groups in EQ5D scores (mean difference, 0.02 points; 95% CI, −0.03 to 0.07 points; P = .42). Furthermore, after adjusting for relevant covariables, there were no between-group differences in EQ5D scores (regression coefficient, 0.00; 95% CI, −0.04 to 0.05; P = .81). There were no between-group differences for any secondary outcomes. There were also no significant interactions for fracture stability (β [SE] , 0.01 [0.05]; P = .82) or previous fracture (β [SE], 0.01 [0.10]; P = .88) and treatment group.Conclusions and Relevance: This randomized clinical trial found that IMNs for the treatment of trochanteric fractures had similar 1-year outcomes compared with SHSs. These results suggest that the SHS is an acceptable lower-cost alternative for trochanteric fractures of the hip.Trial Registration: ClinicalTrials.gov Identifier: NCT01380444

1 July 2016 in Injury
Verified
Journal Article
Closed access
AGAnthony F. De Giacomo
Anthony F. De Giacomo
PTPaul Tornetta
Paul Tornetta
BSBrent J. Sinicrope
Brent J. Sinicrope
PCPatrick K. Cronin
Patrick K. Cronin
PAPeter L. Althausen
Peter L. Althausen
CJChris R. James
Chris R. James

24 October 2017 in JBJS Reviews
Verified
Journal Article
Closed access
PDF file
AMAndrew Marcantonio
Andrew Marcantonio
MPMeredith Pace
Meredith Pace
DBDavid Brabeck
David Brabeck
KNKatharine M. Nault
Katharine M. Nault
ATAllison Trzaskos
Allison Trzaskos
RARachel Anderson
Rachel Anderson
* Femoral-neck fracture in the elderly patient is a common clinical scenario encountered by orthopaedic surgeons. In the United States, approximately 300,000 hip fractures in elderly patients occur each year. Hip fractures are associated with high morbidity, functional disability, and an increased risk of mortality and institutionalization. * Delirium, an acute confusional state, is a common, often unrecognized, and serious postoperative problem in the elderly patient with a femoral-neck fracture. Delirium can contribute to complications, functional disability, loss of independence, mortality, and higher health-care costs. * Multifactorial interventional strategies for delirium prevention offer the best chance to avoid this problem and its associated negative impact on patients, society, and the health-care system.

15 July 2020 in Geriatrics
Verified
Journal Article
Open access
PDF file
MKMichael S Kain
Michael S Kain
DSDavid Saper
David Saper
KLKyle Lybrand
Kyle Lybrand
KBKasey-Jean Bramlett
Kasey-Jean Bramlett
PIPaul Tornetta Iii
Paul Tornetta Iii
AMAndrew Marcantonio
Andrew Marcantonio
In current clinical practice, orthopedic surgeons often delay the surgery intervention on geriatric hip fracture patients to optimize the international normalized ratio (INR), in order to decrease the risk of postoperative hematological complications. However, some evidence suggests that full reversal protocols may not be necessary, especially for patients with prior thromboembolic history. Our study aims to compare the surgical outcomes of patients with normal versus elevated INR values. We conducted a retrospective chart review on 217 patients who underwent surgeries on hip fractures at two academic trauma centers. We found that in our group (n = 124) of patients with an INR value of 1.5–3.0, there was only one reoperation for a hematoma, but there was a trend for more blood transfusions. There was no statistically significant difference in the odds of reoperation or overall complications. Nevertheless, there were significantly more events of postoperative anemia in this high INR patient group.

1 November 2025 in JAAOS: Global Research and Reviews
Verified
Journal Article
Open access
TSThomas M. Seaver
Thomas M. Seaver
ZZZachary Zeller
Zachary Zeller
PTPaul Tornetta
Paul Tornetta
AMAndrew Marcantonio
Andrew Marcantonio
AMAlexander J. Ment
Alexander J. Ment
KCKalyan Chaliki
Kalyan Chaliki
Introduction: The optimal surgical approach for intraarticular calcaneal fractures remains debated. This study compares deep infection rates between the extended lateral (EL) and sinus tarsi (ST) approaches. Methods: A retrospective review was conducted of 782 patients treated surgically for OTA 82B/C calcaneal fractures across 15 institutions. Deep infection was defined as requiring surgical débridement or treatment for osteomyelitis. Risk factors were identified using univariate and multivariate analyses. Results: Of 782 fractures, 444 were treated with EL and 338 with ST. Deep infections occurred in 6.8% of EL and 3.0% of ST cases ( P = 0.017). Multivariate analysis found that surgical approach ( P = 0.03) and age ( P < 0.001) were independent risk factors. EL had more wound complications; ST had more symptomatic implants. Conclusion: The ST approach was associated with lower rates of deep infection and wound complications, even in higher-risk patients.

1 February 2024 in JAAOS: Global Research and Reviews
Verified
Journal Article
Open access
EAEliza Anderson
Eliza Anderson
DSDavid Sing
David Sing
GPGuillermo Pechero
Guillermo Pechero
AHAndrew Hagar
Andrew Hagar
ADAleksey Dvozhinskiy
Aleksey Dvozhinskiy
PTPaul Tornetta
Paul Tornetta
Introduction: The purpose of this study was to evaluate surgeons' ability to perform or supervise a standard operation with agreed-upon radiologic parameters after being on call. Methods: We reviewed a consecutive series of patients with intertrochanteric hip fractures treated with a fixed angle device at 9 centers and compared corrected tip-apex distance and reduction quality for post-call surgeons versus those who were not. Subgroup analyses included surgeons who operated the night before versus not and attending-only versus resident involved cases. Secondary outcomes included union and perioperative complications. Results: One thousand seven hundred fourteen patients were of average age 77 years. Post-call surgeons treated 823 patients and control surgeons treated 891. Surgical corrected tip-apex distance did not differ between groups: on-call 18 mm versus control 18 mm (P = 0.59). The Garden indices were 160° on the AP and 179° on the lateral in both groups. In 66 cases performed by surgeons who operated the night before, the TAD was 17 mm. No difference was noted in corrected tip-apex distance with and without resident involvement (P = 0.101). No difference was observed in pooled fracture-related complications (P = 0.23). Conclusion: Post-call surgeons demonstrated no difference in quality and no increase in complications when performing hip fracture repair the next day compared with surgeons who were not on call.