Daniel Jost

Dr. Daniel Jost

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Research Focus & Metrics

Academic Career Length

30Years (1997-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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22 March 2014 in Intensive Care Medicine
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Journal Article
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WBWulfran Bougouin
Wulfran Bougouin
LLLionel Lamhaut
Lionel Lamhaut
EMEloi Marijon
Eloi Marijon
DJDaniel Jost
Daniel Jost
FDFlorence Dumas
Florence Dumas
XJXavier Jouven
Xavier Jouven

20 April 2017 in European Heart Journal
Verified
Journal Article
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VWVictor Waldmann
Victor Waldmann
KNKumar Narayanan
Kumar Narayanan
NCNicolas Combes
Nicolas Combes
DJDaniel Jost
Daniel Jost
XJXavier Jouven
Xavier Jouven
EMEloi Marijon
Eloi Marijon
Electrical injuries are a commonly encountered hazard in both the home and workplace. However, clinicians are often uncomfortable when faced with the patient who presents with an electric shock due to sparse literature and lack of systematic recommendations on this topic. Electrical injuries can range from minor skin burns to life threatening internal organ damage. A thorough clinical assessment to ascertain the path of current through the body and possible internal injury is essential. The main concern in an apparently stable individual after an electric shock is the potential for delayed occurrence of cardiac arrhythmias which will require monitoring in the intensive care setting. While it may be reasonable to discharge home from the emergency room selected patients with low voltage injuries, absence of syncope and a normal ECG, others may require monitoring for at least 24 h. Public education and increasing workplace as well as home safety measures are key steps in prevention. The present review summarizes current knowledge in pathophysiology, manifestations and management of electrical injuries, with specific focus on cardiac effects.

16 March 2018 in European Heart Journal
Verified
Journal Article
Open access
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VWVictor Waldmann
Victor Waldmann
WBWulfran Bougouin
Wulfran Bougouin
NKNicole Karam
Nicole Karam
FDFlorence Dumas
Florence Dumas
ASArdalan Sharifzadehgan
Ardalan Sharifzadehgan
PIParis-SDEC investigators
Paris-SDEC investigators
Recent studies have shown that in more than half of apparently unexplained sudden cardiac arrests (SCA), a specific aetiology can be unmasked by a careful evaluation. The characteristics and the extent to which such cases undergo a systematic thorough investigation in real-life practice are unknown. Data were analysed from an ongoing study, collecting all cases of out-of-hospital cardiac arrest in Paris area. Investigations performed during the index hospitalization or planned after discharge were gathered to evaluate the completeness of assessment of unexplained SCA. Between 2011 and 2016, among the 18 622 out-of-hospital cardiac arrests, 717 survivors (at hospital discharge) fulfilled the definition of cardiac SCA. Of those, 88 (12.3%) remained unexplained after electrocardiogram, echocardiography, and coronary angiography. Cardiac magnetic resonance imaging yielded the diagnosis in 25 (3.5%) cases, other investigations accounted for 14 (2.4%) additional diagnoses, and 49 (6.8%) patients were labelled as idiopathic ventricular fibrillation (IVF) (48.7 ± 15 years, 69.4% male). Among those labelled IVF, only 8 (16.3%) cases benefited from a complete workup (including pharmacological testing). Younger patients [odds ratio (OR) 6.00, 95% confidence interval (CI) 1.80–22.26] and those admitted to university centres (OR 3.60, 95% CI 1.12–12.45) were more thoroughly investigated. Genetic testing and family screening were initiated in only 9 (18.4%) and 12 (24.5%) cases, respectively. Our findings suggest that complete investigations are carried out in a very low proportion of unexplained SCA. Standardized, systematic approaches need to be implemented to ensure that opportunities for specific therapies and preventive strategies (including relatives) are not missed.

13 April 2010 in Circulation
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DJDaniel Jost
Daniel Jost
HDHervé Degrange
Hervé Degrange
CVCatherine Verret
Catherine Verret
OHOlivier Hersan
Olivier Hersan
IBIsabelle L. Banville
Isabelle L. Banville
TGthe DEFI 2005 Work Group
the DEFI 2005 Work Group
Background— Using automated external defibrillators (AEDs) that implement the Guidelines 2000 resuscitation protocol constrains administration of cardiopulmonary resuscitation (CPR) to <50% of AED connection time. We tested a different AED protocol aimed at increasing the CPR administered to patients with out-of-hospital cardiac arrest. Methods and Results— In a randomized controlled trial, patients with out-of-hospital cardiac arrest requiring defibrillation were treated with 1 of 2 AED protocols. In the control protocol, based on Guidelines 2000, sequences of up to 3 stacked countershocks were delivered, with rhythm analyses initially and after the first and second shocks. The study protocol featured 1 minute of CPR before the first shock, shorter CPR interruptions before and after each shock, and no stacked shocks. The primary end point was survival to hospital admission. Of 5107 out-of-hospital cardiac arrest patients connected to an AED, 1238 required defibrillation, and 845 were included in the final analysis. Study patients (n=421) had shorter preshock pauses (9 versus 19 seconds; P <0.001), had shorter postshock pauses (11 versus 33 seconds; P <0.001), and received more CPR (61% versus 48%; P <0.001) and fewer shocks (2.5 versus 2.9; P <0.001) than control patients (n=424). Similar proportions survived to hospital admission (43.2% versus 42.7%; P =0.87), survived to hospital discharge (13.3% versus 10.6%; P =0.19), achieved return of spontaneous circulation before physician arrival (47.0% versus 48.6%; P =0.65), and survived to 1 year ( P =0.77). Conclusions— Following prompts from AEDs programmed with a protocol similar to Guidelines 2005, firefighters shortened pauses in CPR and improved overall hands-on time, but survival to hospital admission of patients with ventricular fibrillation out-of-hospital cardiac arrest did not improve. Clinical Trial Registration— http://www.clinicaltrials.gov. Unique identifier: NCT00139542.

8 June 2020 in Critical Care
Verified
Journal Article
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RJRomain Jouffroy
Romain Jouffroy
DJDaniel Jost
Daniel Jost
BPBertrand Prunet
Bertrand Prunet

1 December 2014 in Resuscitation
Verified
Journal Article
Closed access
STS. Travers
S. Travers
DJDaniel Jost
Daniel Jost
YGY. Gillard
Y. Gillard
VLV. Lanoë
V. Lanoë
MBM. Bignand
M. Bignand
JTJ.P. Tourtier
J.P. Tourtier