Deborah A. Frank

Dr. Deborah A. Frank


Research Focus & Metrics

Academic Career Length

54Years (1973-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 July 2010 in Pediatrics
Verified
Journal Article
Closed access
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EHErin R. Hager
Erin R. Hager
AQAnna M. Quigg
Anna M. Quigg
MBMaureen M. Black
Maureen M. Black
SCSharon M. Coleman
Sharon M. Coleman
THTimothy Heeren
Timothy Heeren
DFDeborah A. Frank
Deborah A. Frank
OBJECTIVES: To develop a brief screen to identify families at risk for food insecurity (FI) and to evaluate the sensitivity, specificity, and convergent validity of the screen. PATIENTS AND METHODS: Caregivers of children (age: birth through 3 years) from 7 urban medical centers completed the US Department of Agriculture 18-item Household Food Security Survey (HFSS), reports of child health, hospitalizations in their lifetime, and developmental risk. Children were weighed and measured. An FI screen was developed on the basis of affirmative HFSS responses among food-insecure families. Sensitivity and specificity were evaluated. Convergent validity (the correspondence between the FI screen and theoretically related variables) was assessed with logistic regression, adjusted for covariates including study site; the caregivers' race/ethnicity, US-born versus immigrant status, marital status, education, and employment; history of breastfeeding; child's gender; and the child's low birth weight status. RESULTS: The sample included 30 098 families, 23% of which were food insecure. HFSS questions 1 and 2 were most frequently endorsed among food-insecure families (92.5% and 81.9%, respectively). An affirmative response to either question 1 or 2 had a sensitivity of 97% and specificity of 83% and was associated with increased risk of reported poor/fair child health (adjusted odds ratio [aOR]: 1.56; P < .001), hospitalizations in their lifetime (aOR: 1.17; P < .001), and developmental risk (aOR: 1.60; P < .001). CONCLUSIONS: A 2-item FI screen was sensitive, specific, and valid among low-income families with young children. The FI screen rapidly identifies households at risk for FI, enabling providers to target services that ameliorate the health and developmental consequences associated with FI.

23 March 1989 in New England Journal of Medicine
Verified
Journal Article
Closed access
BZBarry Zuckerman
Barry Zuckerman
DFDeborah A. Frank
Deborah A. Frank
RHRalph Hingson
Ralph Hingson
HAHortensia Amaro
Hortensia Amaro
SLSuzette M. Levenson
Suzette M. Levenson
HBHoward Bauchner
Howard Bauchner
To investigate the effects on infants of the use of marijuana and cocaine during pregnancy and to compare the importance of urine assays with that of interviews in ascertaining drug use, we prospectively studied 1226 mothers, recruited from a general prenatal clinic, and their infants. On the basis of either interviews or urine assays conducted prenatally or post partum, 27 percent of the subjects had used marijuana during pregnancy and 18 percent had used cocaine. When only positive urine assays were considered, the corresponding values were 16 percent and 9 percent, respectively.

28 March 2001 in JAMA
Verified
Journal Article
Closed access
PDF file
DFDeborah A. Frank
Deborah A. Frank
MAMarilyn Augustyn
Marilyn Augustyn
WKWanda Grant Knight
Wanda Grant Knight
TPTripler Pell
Tripler Pell
BZBarry Zuckerman
Barry Zuckerman
ContextDespite recent studies that failed to show catastrophic effects of prenatal cocaine exposure, popular attitudes and public policies still reflect the belief that cocaine is a uniquely dangerous teratogen.ObjectiveTo critically review outcomes in early childhood after prenatal cocaine exposure in 5 domains: physical growth; cognition; language skills; motor skills; and behavior, attention, affect, and neurophysiology.Data SourcesSearch of MEDLINE and Psychological Abstracts from 1984 to October 2000.Study SelectionStudies selected for detailed review (1) were published in a peer-reviewed English-language journal; (2) included a comparison group; (3) recruited samples prospectively in the perinatal period; (4) used masked assessment; and (5) did not include a substantial proportion of subjects exposed in utero to opiates, amphetamines, phencyclidine, or maternal human immunodeficiency virus infection.Data ExtractionThirty-six of 74 articles met criteria and were reviewed by 3 authors. Disagreements were resolved by consensus.Data SynthesisAfter controlling for confounders, there was no consistent negative association between prenatal cocaine exposure and physical growth, developmental test scores, or receptive or expressive language. Less optimal motor scores have been found up to age 7 months but not thereafter, and may reflect heavy tobacco exposure. No independent cocaine effects have been shown on standardized parent and teacher reports of child behavior scored by accepted criteria. Experimental paradigms and novel statistical manipulations of standard instruments suggest an association between prenatal cocaine exposure and decreased attentiveness and emotional expressivity, as well as differences on neurophysiologic and attentional/affective findings.ConclusionsAmong children aged 6 years or younger, there is no convincing evidence that prenatal cocaine exposure is associated with developmental toxic effects that are different in severity, scope, or kind from the sequelae of multiple other risk factors. Many findings once thought to be specific effects of in utero cocaine exposure are correlated with other factors, including prenatal exposure to tobacco, marijuana, or alcohol, and the quality of the child's environment. Further replication is required of preliminary neurologic findings.

1 June 2008 in Annals of the New York Academy of Sciences
Verified
Journal Article
Closed access
PDF file
JCJohn T. Cook
John T. Cook
DFDeborah A. Frank
Deborah A. Frank

1 August 2011 in American Journal of Public Health
Verified
Journal Article
Closed access
DCDiana Becker Cutts
Diana Becker Cutts
AMAlan F. Meyers
Alan F. Meyers
MBMaureen M. Black
Maureen M. Black
PCPatrick H. Casey
Patrick H. Casey
MCMariana Chilton
Mariana Chilton
DFDeborah A. Frank
Deborah A. Frank
Objectives. We investigated the association between housing insecurity and the health of very young children. Methods. Between 1998 and 2007, we interviewed 22 069 low-income caregivers with children younger than 3 years who were seen in 7 US urban medical centers. We assessed food insecurity, child health status, developmental risk, weight, and housing insecurity for each child's household. Our indicators for housing insecurity were crowding (> 2 people/bedroom or > 1 family/residence) and multiple moves (≥ 2 moves within the previous year). Results. After adjusting for covariates, crowding was associated with household food insecurity compared with the securely housed (adjusted odds ratio [AOR] = 1.30; 95% confidence interval [CI] = 1.18, 1.43), as were multiple moves (AOR = 1.91; 95% CI = 1.59, 2.28). Crowding was also associated with child food insecurity (AOR = 1.47; 95% CI = 1.34, 1.63), and so were multiple moves (AOR = 2.56; 95% CI = 2.13, 3.08). Multiple moves were associated with fair or poor child health (AOR = 1.48; 95% CI = 1.25, 1.76), developmental risk (AOR 1.71; 95% CI = 1.33, 2.21), and lower weight-for-age z scores (–0.082 vs −0.013; P = .02). Conclusions. Housing insecurity is associated with poor health, lower weight, and developmental risk among young children. Policies that decrease housing insecurity can promote the health of young children and should be a priority.

1 January 2013 in Advances in Nutrition
Verified
Journal Article
Open access
PDF file
JCJohn T. Cook
John T. Cook
MBMaureen Black
Maureen Black
MCMariana Chilton
Mariana Chilton
DCDiana Cutts
Diana Cutts
SCStephanie Ettinger de Cuba
Stephanie Ettinger de Cuba
DFDeborah A. Frank
Deborah A. Frank
This review addresses epidemiological, public health, and social policy implications of categorizing young children and their adult female caregivers