Luis Sardinha

Dr. Luis Sardinha

orcid

Research Focus & Metrics

Academic Career Length

30Years (1997-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 December 2017 in The Lancet
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Journal Article
Open access
LALeandra Abarca-Gómez
Leandra Abarca-Gómez
ZAZiad A Abdeen
Ziad A Abdeen
ZHZargar Abdul Hamid
Zargar Abdul Hamid
NANiveen M Abu-Rmeileh
Niveen M Abu-Rmeileh
BABenjamin Acosta-Cazares
Benjamin Acosta-Cazares
MEMajid Ezzati
Majid Ezzati
Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults. We pooled 2416 population-based studies with measurements of height and weight on 128·9 million participants aged 5 years and older, including 31·5 million aged 5-19 years. We used a Bayesian hierarchical model to estimate trends from 1975 to 2016 in 200 countries for mean BMI and for prevalence of BMI in the following categories for children and adolescents aged 5-19 years: more than 2 SD below the median of the WHO growth reference for children and adolescents (referred to as moderate and severe underweight hereafter), 2 SD to more than 1 SD below the median (mild underweight), 1 SD below the median to 1 SD above the median (healthy weight), more than 1 SD to 2 SD above the median (overweight but not obese), and more than 2 SD above the median (obesity). Regional change in age-standardised mean BMI in girls from 1975 to 2016 ranged from virtually no change (-0·01 kg/m2 per decade; 95% credible interval -0·42 to 0·39, posterior probability [PP] of the observed decrease being a true decrease=0·5098) in eastern Europe to an increase of 1·00 kg/m2 per decade (0·69-1·35, PP>0·9999) in central Latin America and an increase of 0·95 kg/m2 per decade (0·64-1·25, PP>0·9999) in Polynesia and Micronesia. The range for boys was from a non-significant increase of 0·09 kg/m2 per decade (-0·33 to 0·49, PP=0·6926) in eastern Europe to an increase of 0·77 kg/m2 per decade (0·50-1·06, PP>0·9999) in Polynesia and Micronesia. Trends in mean BMI have recently flattened in northwestern Europe and the high-income English-speaking and Asia-Pacific regions for both sexes, southwestern Europe for boys, and central and Andean Latin America for girls. By contrast, the rise in BMI has accelerated in east and south Asia for both sexes, and southeast Asia for boys. Global age-standardised prevalence of obesity increased from 0·7% (0·4-1·2) in 1975 to 5·6% (4·8-6·5) in 2016 in girls, and from 0·9% (0·5-1·3) in 1975 to 7·8% (6·7-9·1) in 2016 in boys; the prevalence of moderate and severe underweight decreased from 9·2% (6·0-12·9) in 1975 to 8·4% (6·8-10·1) in 2016 in girls and from 14·8% (10·4-19·5) in 1975 to 12·4% (10·3-14·5) in 2016 in boys. Prevalence of moderate and severe underweight was highest in India, at 22·7% (16·7-29·6) among girls and 30·7% (23·5-38·0) among boys. Prevalence of obesity was more than 30% in girls in Nauru, the Cook Islands, and Palau; and boys in the Cook Islands, Nauru, Palau, Niue, and American Samoa in 2016. Prevalence of obesity was about 20% or more in several countries in Polynesia and Micronesia, the Middle East and north Africa, the Caribbean, and the USA. In 2016, 75 (44-117) million girls and 117 (70-178) million boys worldwide were moderately or severely underweight. In the same year, 50 (24-89) million girls and 74 (39-125) million boys worldwide were obese. The rising trends in children's and adolescents' BMI have plateaued in many high-income countries, albeit at high levels, but have accelerated in parts of Asia, with trends no longer correlated with those of adults. Wellcome Trust, AstraZeneca Young Health Programme.

1 July 2006 in The Lancet
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Journal Article
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LALars Bo Andersen
Lars Bo Andersen
MHMaarike Harro
Maarike Harro
LSLuis Sardinha
Luis Sardinha
KFKarsten Froberg
Karsten Froberg
UEUlf Ekelund
Ulf Ekelund
SASigmund Alfred Anderssen
Sigmund Alfred Anderssen

17 September 2015 in International Journal of Behavioral Nutrition and Physical Activity
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Journal Article
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ACAshley R. Cooper
Ashley R. Cooper
AGAnna Goodman
Anna Goodman
APAngie S. Page
Angie S. Page
Lauren SherarLauren Sherar
Lauren Sherar
DEDale W. Esliger
Dale W. Esliger
UEUlf Ekelund
Ulf Ekelund
Physical activity and sedentary behaviour in youth have been reported to vary by sex, age, weight status and country. However, supporting data are often self-reported and/or do not encompass a wide range of ages or geographical locations. This study aimed to describe objectively-measured physical activity and sedentary time patterns in youth. The International Children’s Accelerometry Database (ICAD) consists of ActiGraph accelerometer data from 20 studies in ten countries, processed using common data reduction procedures. Analyses were conducted on 27,637 participants (2.8–18.4 years) who provided at least three days of valid accelerometer data. Linear regression was used to examine associations between age, sex, weight status, country and physical activity outcomes. Boys were less sedentary and more active than girls at all ages. After 5 years of age there was an average cross-sectional decrease of 4.2 % in total physical activity with each additional year of age, due mainly to lower levels of light-intensity physical activity and greater time spent sedentary. Physical activity did not differ by weight status in the youngest children, but from age seven onwards, overweight/obese participants were less active than their normal weight counterparts. Physical activity varied between samples from different countries, with a 15–20 % difference between the highest and lowest countries at age 9–10 and a 26–28 % difference at age 12–13. Physical activity differed between samples from different countries, but the associations between demographic characteristics and physical activity were consistently observed. Further research is needed to explore environmental and sociocultural explanations for these differences.

8 May 2019 in Nature
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Yousef KhaderYousef Khader
Yousef Khader
HBHonor Bixby
Honor Bixby
JBJames Bentham
James Bentham
BZBin Zhou
Bin Zhou
MCMariachiara Di Cesare
Mariachiara Di Cesare
MEMajid Ezzati
Majid Ezzati
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities1,2. This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity3–6. Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55% of the global rise in mean BMI from 1985 to 2017—and more than 80% in some low- and middle-income regions—was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing—and in some countries reversal—of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories.

1 January 2004 in Medicine & Science in Sports & Exercise
Verified
Journal Article
Closed access
CRChris J. Riddoch
Chris J. Riddoch
LALars Bo Andersen
Lars Bo Andersen
NWNiels Wedderkopp
Niels Wedderkopp
MHMaarike Harro
Maarike Harro
LKLena Klasson-Heggebø
Lena Klasson-Heggebø
UEUlf Ekelund
Ulf Ekelund
Was to assess physical activity levels and patterns from children participating in the European Youth Heart Study (EYHS). Very limited physical activity data exist that have been collected from representative samples of children and even fewer data collected where physical activity has been measured using objective methods. Methods Subjects were 2185 children aged 9 and 15 yr from Denmark, Portugal, Estonia, and Norway. Physical activity data were obtained using MTI (formerly CSA) accelerometers. The primary outcome variable was established as the child’s activity level (accelerometer counts per minute). Children wore the accelerometer for 3 or 4 d, which included at least 1 weekend day. Results Boys were more active than girls at age 9 (784 ± 282 vs 649 ± 204 counts·min−1) and 15 yr (615 ± 228 vs 491 ± 163 counts·min−1). With respect to time engaged in moderate-intensity activity, gender differences were apparent at age 9 (192 ± 66 vs 160 ± 54 min·d−1) and age 15 (99 ± 45 vs 73 ± 32 min·d−1). At age 9, the great majority of boys and girls achieved current health-related physical activity recommendations (97.4% and 97.6%, respectively). At age 15, fewer children achieved the guidelines and gender differences were apparent (boys 81.9% vs girls 62.0%). Conclusions Accelerometers are a feasible and accurate instrument for use in large epidemiological studies of children’s activity. Boys tend to be more active than girls, and there is a marked reduction in activity over the adolescent years. The great majority of younger children achieve current physical activity recommendations, whereas fewer older children do so—especially older girls....

12 December 2006 in PLOS Medicine
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Journal Article
Open access
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UEUlf Ekelund
Ulf Ekelund
SBSøren Brage
Søren Brage
KFKarsten Froberg
Karsten Froberg
MHMaarike Harro
Maarike Harro
SASigmund A Anderssen
Sigmund A Anderssen
LALars Bo Andersen
Lars Bo Andersen
TV viewing has been linked to metabolic-risk factors in youth. However, it is unclear whether this association is independent of physical activity (PA) and obesity. We did a population-based, cross-sectional study in 9- to 10-y-old and 15- to 16-y-old boys and girls from three regions in Europe (n = 1,921). We examined the independent associations between TV viewing, PA measured by accelerometry, and metabolic-risk factors (body fatness, blood pressure, fasting triglycerides, inverted high-density lipoprotein (HDL) cholesterol, glucose, and insulin levels). Clustered metabolic risk was expressed as a continuously distributed score calculated as the average of the standardized values of the six subcomponents. There was a positive association between TV viewing and adiposity (p = 0.021). However, after adjustment for PA, gender, age group, study location, sexual maturity, smoking status, birth weight, and parental socio-economic status, the association of TV viewing with clustered metabolic risk was no longer significant (p = 0.053). PA was independently and inversely associated with systolic and diastolic blood pressure, fasting glucose, insulin (all p < 0.01), and triglycerides (p = 0.02). PA was also significantly and inversely associated with the clustered risk score (p < 0.0001), independently of obesity and other confounding factors. TV viewing and PA may be separate entities and differently associated with adiposity and metabolic risk. The association between TV viewing and clustered metabolic risk is mediated by adiposity, whereas PA is associated with individual and clustered metabolic-risk indicators independently of obesity. Thus, preventive action against metabolic risk in children may need to target TV viewing and PA separately.