The introduction of the ”dual carbon” target has increased the need for products that can accurately measure carbon dioxide levels, reflecting the rising demand. Due to challenges in achieving the required spatiotemporal resolution, accuracy, and spatial continuity with current carbon dioxide concentration products, it is essential to explore methods for obtaining carbon dioxide concentration products with completeness in space and time. Based on the 2018 OCO-2 carbon dioxide products and environmental variables such as vegetation coverage (FVC, LAI), net primary productivity (NPP), relative humidity (RH), evapotranspiration (ET), temperature (T) and wind (U, V), this study constructed a multiple regression model to obtain the spatial continuous carbon dioxide concentration products in the provinces of Huai River Basin. Using indicators such as correlation coefficient, root mean square error (RMSE), local variance, and percentage of valid pixels, the performance of model was validated. The validation results are shown as follows: (1) Among the selected environmental variables, the primary factors affecting the spatiotemporal distribution of carbon dioxide concentration are ET, LAI, FVC, NPP, T, U, and RH. (2) Compared with the OCO-2 carbon dioxide products, the percentage of valid pixels of the reconstructed carbon dioxide concentration data increased from less than 1% to over 90%. (3) The local variance in reconstructed data was significantly larger than that of original OCO-2 ${\mathrm{C}\mathrm{O}}_2$ products. (4) The average monthly RMSE is 2.69. Therefore, according to the model developed in this study, we can obtain a carbon dioxide concentration dataset that is spatially complete, meets precision requirements, and is rich in local detail information, which can better reflect the spatial pattern of carbon dioxide concentration and can be used to examine the carbon cycle between the terrestrial environment, biosphere, and atmosphere.