Prof. Dr. Markus W. Hollmann is a Principal Investigator and a Full Professor at the Department of Anesthesiology, Amsterdam University Medical Centers. He specializes in Anesthesiology, Intensive Care, Emergency Medicine, Pain Therapy, and Palliative Care. Prof. Hollmann is a well-renowned expert in the effects of anesthetics, in particular local anesthetics (LA), on signal transduction of G-protein coupled receptors (GPCRs). His findings on LA interactions with specific G protein subunits and G protein signaling transduction pathways have led to a revival of the systemic use of LA in the perioperative setting for indications other than pain management (e.g., modulation of inflammation and coagulation). He is a part of the Protective Ventilation Network (PROVENET), the leading investigator for the ZONMW-supported PANAMA and DEPTHHip trial, and the Principal Investigator for the ZONMW-funded national TRACE trial. In addition, he is part of the NIMIT consortium (STW funded) and national coordinator for the EU COST project on anesthesia and cancer.