Materials with antimicrobial properties and high adsorption capabilities are crucial for managing exudate in post-surgical cases. However, achieving both properties simultaneously remains a challenge. In this study, we first synthesized curcumin-loaded organosolv lignin nanoparticles (Lig-Cur Nps) using a solvent-shifting approach in a continuous flow reactor. These Lig-Cur NPs were then dispersed in a polyvinyl alcohol (PVA) solution. The PVA-Lig-Cur NP colloidal suspension was further crosslinked with tannic acid (TA) through hydrogen bonding interactions. A simple freeze–thaw cycle of the PVA-Lig-Cur NP suspension with TA resulted in the formation of a stable gel, which was then lyophilized to fabricate the PVA-Lig-Cur-TA hydrogel scaffold. This scaffold features an interconnected microporous network with a swelling percentage of 800%, enabling the rapid adsorption of exudates. Its excellent properties and antimicrobial efficacy against Staphylococcus aureus, a bacterium commonly found on the skin, and Pseudomonas aeruginosa highlight its potential to effectively remove exudates while preventing bacterial colonization.

Cover Picture: A Corona plasma jet was moved along the substrate with a constant speed and an increasing oxygen amount while maintaining constant the other deposition parameters including hexamethyldisiloxane flow rate. The gradual incorporation of oxygen into siloxane‐based coating led to the formation of wettability gradient along the coating primarily as a result of increase in surface polar groups (chemistry effect) and next due to the surface roughness variation (physical effect).