Lulu Zhang

Prof. Lulu Zhang

second military medical university
orcid

Research Focus & Metrics

Academic Career Length

18Years (2009-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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BTBihan Tang
Bihan Tang
QDQiangyu Deng
Qiangyu Deng
DGDeborah Glik
Deborah Glik
JDJunqiang Dong
Junqiang Dong
LZLulu Zhang
Lulu Zhang
PTSD is considered the most common negative psychological reactions among survivors following an earthquake. The present study sought to find out the determinants of PTSD in earthquake survivors using a systematic meta-analysis. Four electronic databases (PubMed, Embase, Web of Science, and PsycInfo) were used to search for observational studies about PTSD following earthquakes. The literature search, study selection, and data extraction were conducted independently by two authors. 52 articles were included in the study. Summary estimates, subgroup analysis, and publication bias tests were performed on the data. The prevalence of PTSD after earthquakes ranged from 4.10% to 67.07% in adults and from 2.50% to 60.00% in children. For adults, the significant predictors were being female, low education level or socio-economic status, prior trauma; being trapped, experiencing fear, injury, or bereavement during the disaster. For children, the significant predictors were being older age, high education level; being trapped, experiencing fear, injury, or bereavement, witnessing injury/death during the earthquakes. Our study provides implications for the understanding of risk factors for PTSD among earthquake survivors. Post-disaster mental health recovery programs that include early identification, on-going monitoring, and sustained psychosocial support are needed for earthquake survivors.

QDQiangyu Deng
Qiangyu Deng
BTBihan Tang
Bihan Tang
CXChen Xue
Chen Xue
YLYuan liu
Yuan liu
XLXu Liu
Xu Liu
LZLulu Zhang
Lulu Zhang
Background: Description of the anatomical severity of injuries in trauma patients is important. While the Injury Severity Score has been regarded as the “gold standard” since its creation, several studies have indicated that the New Injury Severity Score is better. Therefore, we aimed to systematically evaluate and compare the accuracy of the Injury Severity Score and the New Injury Severity Score in predicting mortality. Methods: Two researchers independently searched the PubMed, Embase, and Web of Science databases and included studies from which the exact number of true-positive, false-positive, false-negative, and true-negative results could be extracted. Quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies checklist criteria. The meta-analysis was performed using Meta-DiSc. Meta-regression, subgroup analyses, and sensitivity analyses were conducted to determine the source(s) of heterogeneity and factor(s) affecting the accuracy of the New Injury Severity Score and the Injury Severity Score in predicting mortality. Results: The heterogeneity of the 11 relevant studies (total n = 11,866) was high (I2 > 80%). The meta-analysis using a random-effects model resulted in sensitivity of 0.64, specificity of 0.93, positive likelihood ratio of 5.11, negative likelihood ratio of 0.27, diagnostic odds ratio of 27.75, and area under the summary receiver operator characteristic curve of 0.9009 for the Injury Severity Score; and sensitivity of 0.71, specificity of 0.87, positive likelihood ratio of 5.22, negative likelihood ratio of 0.20, diagnostic odds ratio of 24.74, and area under the summary receiver operating characteristic curve of 0.9095 for the New Injury Severity Score. Conclusion: The New Injury Severity Score and the Injury Severity Score have similar abilities in predicting mortality. Further research is required to determine the appropriate use of the Injury Severity Score or the New Injury Severity Score based on specific patient condition and trauma type.

PKPeng Kang
Peng Kang
BTBihan Tang
Bihan Tang
YLYuan liu
Yuan liu
XLXu Liu
Xu Liu
ZLZhipeng Liu
Zhipeng Liu
LZLulu Zhang
Lulu Zhang
The aim of this paper is to investigate medical efforts and injury profiles of victims of the Lushan earthquake admitted to three military hospitals. This study retrospectively investigated the clinical records of 266 admitted patients evacuated from the Lushan earthquake area. The 2005 version of the Abbreviated Injury Scale (AIS-2005) was used to identify the severity of each injury. Patient demographic data, complaints, diagnoses, injury types, prognosis, means of transportation, and cause of injury were all reviewed individually. The statistical analysis of the study was conducted primarily using descriptive statistics. Of the 266 patients, 213 (80.1%) were admitted in the first two days. A total of 521 injury diagnoses were recorded in 266 patients. Earthquake-related injuries were primarily caused by buildings collapsing (38.4%) and victims being struck by objects (33.8%); the most frequently injured anatomic sites were the lower extremities and pelvis (34.2%) and surface area of the body (17.9%). Fracture (41.5%) was the most frequent injury, followed by soft tissue injury (27.5%), but crush syndrome was relatively low (1.2%) due to the special housing structures in the Lushan area. The most commonly used procedure was suture and dressings (33.7%), followed by open reduction and internal fixation (21.9%).The results of this study help formulate recommendations to improve future disaster relief and emergency planning in remote, isolated, and rural regions of developing countries.

1 December 2015 in Psychiatry Research
Verified
Journal Article
Closed access
PKPeng Kang
Peng Kang
YLYipeng Lv
Yipeng Lv
LHLu Hao
Lu Hao
BTBihan Tang
Bihan Tang
ZLZhipeng Liu
Zhipeng Liu
LZLulu Zhang
Lulu Zhang

1 October 2015 in Journal of Biomedical Informatics
Verified
Journal Article
Open access
WYWenya Yu
Wenya Yu
MLMeina Li
Meina Li
YGYang Ge
Yang Ge
LLLing Li
Ling Li
YZYi Zhang
Yi Zhang
LZLulu Zhang
Lulu Zhang
The increasing of potential medical demand in China has threatened the health of the population, the medical equity, accessibility to medical services, and has impeded the development of Chinese health delivery system. This study aims to understand the mechanism of the increasing potential medical demand and find some solutions. We constructed a system dynamics model to analyze and simulate this problem, to predict the influences of health policies on the actual percentage of patients not seeking medical care (adjusting the quantity structure of hospitals and community health systems (CHSs), adjusting outpatient prices, and adjusting the level of health insurance). Decreasing the number of hospitals, increasing the number of CHSs, and raising the proportion of health insurance compensation would effectively increase the transformation of potential medical demand. But currently, changes of the outpatient prices didn't play a role in the transformation of potential medical demand. Combined with validation analysis and model simulation, we suggest some possible solutions. The main factors causing potential medical demand are accessibility to medical services and proportion of health insurance compensation. Thus, adjusting the number of hospitals and CHSs and increasing the proportion of health insurance compensation should decrease the actual percentage of patients not seeking medical care and accelerate the transformation of potential medical demand, which deserved being concerned in policymaking.

18 September 2024 in Frontiers in Cardiovascular Medicine
Verified
Journal Article
Open access
PDF file
MZMenglan Zhu
Menglan Zhu
WJWenyu Jin
Wenyu Jin
WHWangbiao He
Wangbiao He
LZLulu Zhang
Lulu Zhang
Background: Cardiovascular diseases (CVDs) are not only the primary cause of mortality in China but also represent a significant financial burden. The World Health Organization highlight that as China undergoes rapid socioeconomic development, its disease spectrum is gradually shifting towards that of developed countries, with increasing prevalence of lifestyle-related diseases such as ischemic heart disease and stroke. We reviewed the rates and trends of CVDs incidence, mortality and disability-adjusted life years (DALYs) burden in China and compared them with those in the United States (US) and Japan for formulating CVDs control policies.Methods: Data on CVDs incidence, death and DALYs in China, the US and Japan were obtained from the GBD 2019 database. The Joinpoint regression model was used to analyze the trends in CVDs incidence and mortality in China, the US and Japan, calculate the annual percentage change and determine the best-fitting inflection points.Results: In 2019, there were approximately 12,341,074 new diagnosed cases of CVDs in China, with 4,584,273 CVDs related deaths, causing 91,933,122 DALYs. The CVDs age-standardized incidence rate (ASIR) in China (538.10/100,000) was lower than that in the US and globally, while age-standardized death rate (ASDR) (276.9/100,000) and age-standardized DALY rate (6,463.47/100,000) were higher than those in the two regions. Compared with the US and Japan, from 1990 to 2019, the CVDs incidence rate in China showed an increasing trend, with a lower annual decrease in ASDR and a younger age structure of disease burden. Furthermore, the disease spectrum in China changed minimally, with stroke, ischemic heart disease, and hypertensive heart disease being the top three leading CVDs diseases in terms of incidence and disease burden, also being the major causes of CVDs in the US and Japan.Conclusion: The prevention and control of CVDs is a global issue. The aging population and increasing unhealthy lifestyles will continue to increase the burden in China. Therefore, relevant departments in China should reference the established practices for CVDs control in developed countries while considering the diversity of CVDs in different regions when adjusting national CVDs control programs.