Takuma Hayashi is a professor at Section Head, National Hospital Organization Kyoto Medical Center, Japan. He received his Ph.D. and MBBS. from the University of Tokyo in 1994. He was in research training as a resident staff member at the National Cancer Center, Tokyo, Japan, for 3 years until 1994, and joined WI/M.I.T. that year. He completed postdoctoral training in the laboratory of Dr. Rick A. Young (WI/M.I.T.). After postdoctoral training, he achieved a lecturer position at Harvard Medical School in 1997. He has been studying the antigen presentation system by MHC class I with LMP2-deficient mice under the cooperation of Dr. Susumu Tonegawa (Nobel Laureate, M.I.T.). He identifies diagnostic biomarkers, LMP2, Cyclin B1, and Cyclin E, for malignant tumors, i.e., uterine leiomyosarcoma and BRCA1 and S100A4 for ovarian carcinoma. His current research focus is on a molecular approach to tumorigenesis of uterine leiomyosarcoma and ovarian cancer.