Paul Fergus

Prof. Paul Fergus

University of Liverpool, Liverpool, UK
orcid

Research Focus & Metrics

Academic Career Length

24Years (2003-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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28 October 2013 in PLOS ONE
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Journal Article
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Paul FergusPaul Fergus
Paul Fergus
PCPauline Cheung
Pauline Cheung
AHAbir Hussain
Abir Hussain
Dhiya  Al-JumeilyDhiya Al-Jumeily
Dhiya Al-Jumeily
CDChelsea Dobbins
Chelsea Dobbins
SIShamaila Iram
Shamaila Iram
There has been some improvement in the treatment of preterm infants, which has helped to increase their chance of survival. However, the rate of premature births is still globally increasing. As a result, this group of infants are most at risk of developing severe medical conditions that can affect the respiratory, gastrointestinal, immune, central nervous, auditory and visual systems. In extreme cases, this can also lead to long-term conditions, such as cerebral palsy, mental retardation, learning difficulties, including poor health and growth. In the US alone, the societal and economic cost of preterm births, in 2005, was estimated to be $26.2 billion, per annum. In the UK, this value was close to £2.95 billion, in 2009. Many believe that a better understanding of why preterm births occur, and a strategic focus on prevention, will help to improve the health of children and reduce healthcare costs. At present, most methods of preterm birth prediction are subjective. However, a strong body of evidence suggests the analysis of uterine electrical signals (Electrohysterography), could provide a viable way of diagnosing true labour and predict preterm deliveries. Most Electrohysterography studies focus on true labour detection during the final seven days, before labour. The challenge is to utilise Electrohysterography techniques to predict preterm delivery earlier in the pregnancy. This paper explores this idea further and presents a supervised machine learning approach that classifies term and preterm records, using an open source dataset containing 300 records (38 preterm and 262 term). The synthetic minority oversampling technique is used to oversample the minority preterm class, and cross validation techniques, are used to evaluate the dataset against other similar studies. Our approach shows an improvement on existing studies with 96% sensitivity, 90% specificity, and a 95% area under the curve value with 8% global error using the polynomial classifier.

29 January 2015 in BioMed Research International
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Journal Article
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Paul FergusPaul Fergus
Paul Fergus
DHDavid Hignett
David Hignett
AHAbir Jaafar Hussain
Abir Jaafar Hussain
Dhiya  Al-JumeilyDhiya Al-Jumeily
Dhiya Al-Jumeily
KAKhaled Abdel-Aziz
Khaled Abdel-Aziz
The epilepsies are a heterogeneous group of neurological disorders and syndromes characterised by recurrent, involuntary, paroxysmal seizure activity, which is often associated with a clinicoelectrical correlate on the electroencephalogram. The diagnosis of epilepsy is usually made by a neurologist but can be difficult to be made in the early stages. Supporting paraclinical evidence obtained from magnetic resonance imaging and electroencephalography may enable clinicians to make a diagnosis of epilepsy and investigate treatment earlier. However, electroencephalogram capture and interpretation are time consuming and can be expensive due to the need for trained specialists to perform the interpretation. Automated detection of correlates of seizure activity may be a solution. In this paper, we present a supervised machine learning approach that classifies seizure and nonseizure records using an open dataset containing 342 records. Our results show an improvement on existing studies by as much as 10% in most cases with a sensitivity of 93%, specificity of 94%, and area under the curve of 98% with a 6% global error using ak-class nearest neighbour classifier. We propose that such an approach could have clinical applications in the investigation of patients with suspected seizure disorders.

20 April 2022 in Sensors
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SGSean T Givnan
Sean T Givnan
Carl ChalmersCarl Chalmers
Carl Chalmers
Paul FergusPaul Fergus
Paul Fergus
Sandra Ortega-MartorellSandra Ortega-Martorell
Sandra Ortega-Martorell
TWTom Whalley
Tom Whalley
Rotary machine breakdown detection systems are outdated and dependent upon routine testing to discover faults. This is costly and often reactive in nature. Real-time monitoring offers a solution for detecting faults without the need for manual observation. However, manual interpretation for threshold anomaly detection is often subjective and varies between industrial experts. This approach is ridged and prone to a large number of false positives. To address this issue, we propose a machine learning (ML) approach to model normal working operations and detect anomalies. The approach extracts key features from signals representing a known normal operation to model machine behaviour and automatically identify anomalies. The ML learns generalisations and generates thresholds based on fault severity. This provides engineers with a traffic light system where green is normal behaviour, amber is worrying and red signifies a machine fault. This scale allows engineers to undertake early intervention measures at the appropriate time. The approach is evaluated on windowed real machine sensor data to observe normal and abnormal behaviour. The results demonstrate that it is possible to detect anomalies within the amber range and raise alarms before machine failure.

6 July 2017 in BioMedical Engineering OnLine
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Journal Article
Open access
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Paul FergusPaul Fergus
Paul Fergus
AHAbir Jaafar Hussain
Abir Jaafar Hussain
Dhiya  Al-JumeilyDhiya Al-Jumeily
Dhiya Al-Jumeily
DHDe-Shuang Huang
De-Shuang Huang
Nizar BouguilaNizar Bouguila
Nizar Bouguila
Visual inspection of cardiotocography traces by obstetricians and midwives is the gold standard for monitoring the wellbeing of the foetus during antenatal care. However, inter- and intra-observer variability is high with only a 30% positive predictive value for the classification of pathological outcomes. This has a significant negative impact on the perinatal foetus and often results in cardio-pulmonary arrest, brain and vital organ damage, cerebral palsy, hearing, visual and cognitive defects and in severe cases, death. This paper shows that using machine learning and foetal heart rate signals provides direct information about the foetal state and helps to filter the subjective opinions of medical practitioners when used as a decision support tool. The primary aim is to provide a proof-of-concept that demonstrates how machine learning can be used to objectively determine when medical intervention, such as caesarean section, is required and help avoid preventable perinatal deaths. This is evidenced using an open dataset that comprises 506 controls (normal virginal deliveries) and 46 cases (caesarean due to pH ≤ 7.20—acidosis, n = 18; pH > 7.20 and pH < 7.25—foetal deterioration, n = 4; or clinical decision without evidence of pathological outcome measures, n = 24). Several machine-learning algorithms are trained, and validated, using binary classifier performance measures. The findings show that deep learning classification achieves sensitivity = 94%, specificity = 91%, Area under the curve = 99%, F-score = 100%, and mean square error = 1%. The results demonstrate that machine learning significantly improves the efficiency for the detection of caesarean section and normal vaginal deliveries using foetal heart rate signals compared with obstetrician and midwife predictions and systems reported in previous studies.

1 February 2018 in Computers in Biology and Medicine
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Journal Article
Closed access
Paul FergusPaul Fergus
Paul Fergus
MSMalarvizhi Selvaraj
Malarvizhi Selvaraj
Carl ChalmersCarl Chalmers
Carl Chalmers

16 April 2019 in Sensors
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Journal Article
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SSamuel Ryecroft
Samuel Ryecroft
ASAndy Shaw
Andy Shaw
Paul FergusPaul Fergus
Paul Fergus
Patryk KotPatryk Kot
Patryk Kot
Khalid HashimKhalid Hashim
Khalid Hashim
LCLaura Conway
Laura Conway
In 2016, there were 317 serious water pollution incidents in the UK, with 78,000 locations where businesses discharge controlled quantities of pollutants into rivers; therefore, continuous monitoring is vital. Since 1998, the environment agency has taken over 50 million water samples for water quality monitoring. The Internet of Things has grown phenomenally in recent years, reaching all aspects of our lives, many of these connected devices use wireless sensor networks to relay data to internet-connected nodes, where data can be processed, analyzed and consumed. However, Underwater wireless communications rely mainly on alternative communication methods such as optical and acoustic, with radio frequencies being an under-exploited method. This research presents real world results conducted in the Leeds and Liverpool Canal for the novel use of the 433 MHz radio frequency combined with a bowtie antenna in underwater communications in raw water, achieving distances of 7 m at 1.2 kbps and 5 m at 25 kbps.